ID W6TIP1_9SPIR Unreviewed; 378 AA.
AC W6TIP1;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=thymidine kinase {ECO:0000256|ARBA:ARBA00012118};
DE EC=2.7.1.21 {ECO:0000256|ARBA:ARBA00012118};
GN ORFNames=BDCR2A_00970 {ECO:0000313|EMBL:ETZ18997.1};
OS Borrelia duttonii CR2A.
OC Bacteria; Spirochaetota; Spirochaetia; Spirochaetales; Borreliaceae;
OC Borrelia.
OX NCBI_TaxID=1432657 {ECO:0000313|EMBL:ETZ18997.1, ECO:0000313|Proteomes:UP000019148};
RN [1] {ECO:0000313|EMBL:ETZ18997.1, ECO:0000313|Proteomes:UP000019148}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CR2A {ECO:0000313|EMBL:ETZ18997.1,
RC ECO:0000313|Proteomes:UP000019148};
RA Schwan T.G., Raffel S.J., Porcella S.F.;
RT "Comparative genomics of relapsing fever spirochetes.";
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thymidine kinase family.
CC {ECO:0000256|ARBA:ARBA00007587}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETZ18997.1}.
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DR EMBL; AZIT01000001; ETZ18997.1; -; Genomic_DNA.
DR AlphaFoldDB; W6TIP1; -.
DR PATRIC; fig|1432657.3.peg.958; -.
DR Proteomes; UP000019148; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004797; F:thymidine kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0071897; P:DNA biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.30.60.20; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001267; Thymidine_kinase.
DR Pfam; PF00265; TK; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA synthesis {ECO:0000256|ARBA:ARBA00022634};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:ETZ18997.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000019148};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:ETZ18997.1}.
SQ SEQUENCE 378 AA; 43903 MW; F2F61CD6E4FC12EE CRC64;
MSYVWGEFVF MGFYLNLVNG DTRSKLDNIV SISHFNFKDN SNLMLIIGPM GSGKTEYAAK
IYKDSLIIKN KSSEILASIT RGLRNRANVF FIRNILDKKR FKNYPENVIP YRGGGSDEIE
GVDFASDSFD VGQLIEKNPE YGTFIIDETC FYDERLVFIV NKIALDLNVL FILPTLLYNF
RKEIFNNTAR LLIEYADKIC SLGAYCEHIN CMDESFLTYR YYFYEGKEIA APYFDPLLIV
GGDEIVESAI YPNYATRCSK HHYLVGREYF FTILKPFALL YIQGDRKFLE REIVDLKSNI
VNSNFQKSLL IEVGEKYDIT ILENVLKLPF LAERALITLS FEYNILSKED FKEIVNRFSL
SKDYIQKVIV SREYKGIF
//
