ID W6TSA1_9SPHI Unreviewed; 648 AA.
AC W6TSA1;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE RecName: Full=Alpha-glucosidase {ECO:0008006|Google:ProtNLM};
GN ORFNames=N824_25275 {ECO:0000313|EMBL:ETZ22243.1};
OS Pedobacter sp. V48.
OC Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC Sphingobacteriaceae; Pedobacter.
OX NCBI_TaxID=509635 {ECO:0000313|EMBL:ETZ22243.1, ECO:0000313|Proteomes:UP000019145};
RN [1] {ECO:0000313|EMBL:ETZ22243.1, ECO:0000313|Proteomes:UP000019145}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=V48 {ECO:0000313|EMBL:ETZ22243.1,
RC ECO:0000313|Proteomes:UP000019145};
RX PubMed=24578271;
RA Bitzer A.S., Garbeva P., Silby M.W.;
RT "Draft Genome Sequence of Pedobacter sp. Strain V48, Isolated from a
RT Coastal Sand Dune in the Netherlands.";
RL Genome Announc. 2:e00094-e00014(2014).
CC -!- COFACTOR:
CC Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC Evidence={ECO:0000256|ARBA:ARBA00001913};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETZ22243.1}.
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DR EMBL; AWRU01000013; ETZ22243.1; -; Genomic_DNA.
DR STRING; 509635.N824_25275; -.
DR PATRIC; fig|509635.5.peg.2766; -.
DR eggNOG; COG0710; Bacteria.
DR Proteomes; UP000019145; Unassembled WGS sequence.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:UniProt.
DR GO; GO:0008152; P:metabolic process; IEA:UniProtKB-KW.
DR Gene3D; 2.70.98.10; -; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR014718; GH-type_carb-bd.
DR InterPro; IPR029483; GH97_C.
DR InterPro; IPR019563; GH97_catalytic.
DR InterPro; IPR029486; GH97_N.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR35803; GLUCAN 1,4-ALPHA-GLUCOSIDASE SUSB-RELATED; 1.
DR PANTHER; PTHR35803:SF2; RETAINING ALPHA-GALACTOSIDASE; 1.
DR Pfam; PF14509; GH97_C; 1.
DR Pfam; PF14508; GH97_N; 1.
DR Pfam; PF10566; Glyco_hydro_97; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..648
FT /note="Alpha-glucosidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004882231"
FT DOMAIN 29..273
FT /note="Glycosyl-hydrolase 97 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF14508"
FT DOMAIN 278..543
FT /note="Glycosyl-hydrolase 97 catalytic"
FT /evidence="ECO:0000259|Pfam:PF10566"
FT DOMAIN 546..641
FT /note="Glycosyl-hydrolase 97 C-terminal oligomerisation"
FT /evidence="ECO:0000259|Pfam:PF14509"
SQ SEQUENCE 648 AA; 72427 MW; F2FB5BC1F1263C67 CRC64;
MKPNPVLAIF LFIFCLSAEL DAKDKSYQLS APNNTLKVKV NIGDGITYSV SFKNKIVILP
SAIAMILQNK VLGKAAQVKN TRTLRGKDFN ELSIEMSDQG YSLIFRAYDE GIAYRFVTNF
KDSIQVVAEK ATFNINGKPA AILQETDNYT SWEGPYARHA SIAEISSGKR ATTPALFDDK
STGIKVVIAE SDLFGYPGMY IQKQGAQYIG DWAKYPTKAV MGSWGDFVSV VKERGNFLAK
TDGNRAFPWR VIIATDNDKG LLDNHLVTRL ARPSEIKDTS WIKPGXXXXX WWHDAMLPGA
SIPSGMENRN TALYNYYVDF AAANKLEYMM IDAGWSNNYD LTKVNPKLDV QGVIKRAREK
NVGIFLWCVA STLLKDLNKN LDFLRSIGAA GIKVDFFDRD DQEAIQWLER IAKEAAKRKL
MIDFHGCSKP TGLETTYPNI VNYEAVRGAE SDKWDYTINP DHHLIIPFVR MLAGPFDYTP
GAMRNKTKTA FRPIDPGLPS GQGTRCHELA MYVIYDQPLG MLADSPTEYE SVPDIMTYLS
AVPTVADETK VIDAKLAEYI VMAKRKGENW YVGAMTNWTS RNLKLDFSFL KPGVNYTAQI
YTDAQDADVN ATHYDLKTIS VNNHTKIDLK LSSGGGAAIM IEKSIFKK
//
