ID W6TZT4_ECHGR Unreviewed; 301 AA.
AC W6TZT4;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=NAD(+) ADP-ribosyltransferase {ECO:0000256|ARBA:ARBA00012020};
DE EC=2.4.2.30 {ECO:0000256|ARBA:ARBA00012020};
GN ORFNames=EGR_10799 {ECO:0000313|EMBL:EUB54345.1};
OS Echinococcus granulosus (Hydatid tapeworm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC Eucestoda; Cyclophyllidea; Taeniidae; Echinococcus;
OC Echinococcus granulosus group.
OX NCBI_TaxID=6210 {ECO:0000313|EMBL:EUB54345.1, ECO:0000313|Proteomes:UP000019149};
RN [1] {ECO:0000313|EMBL:EUB54345.1, ECO:0000313|Proteomes:UP000019149}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24013640; DOI=10.1038/ng.2757;
RA Zheng H., Zhang W., Zhang L., Zhang Z., Li J., Lu G., Zhu Y., Wang Y.,
RA Huang Y., Liu J., Kang H., Chen J., Wang L., Chen A., Yu S., Gao Z.,
RA Jin L., Gu W., Wang Z., Zhao L., Shi B., Wen H., Lin R., Jones M.K.,
RA Brejova B., Vinar T., Zhao G., McManus D.P., Chen Z., Zhou Y., Wang S.;
RT "The genome of the hydatid tapeworm Echinococcus granulosus.";
RL Nat. Genet. 45:1168-1175(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=NAD(+) + (ADP-D-ribosyl)n-acceptor = nicotinamide + (ADP-D-
CC ribosyl)n+1-acceptor + H(+).; EC=2.4.2.30;
CC Evidence={ECO:0000256|ARBA:ARBA00033987};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EUB54345.1}.
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DR EMBL; APAU02000272; EUB54345.1; -; Genomic_DNA.
DR AlphaFoldDB; W6TZT4; -.
DR STRING; 6210.W6TZT4; -.
DR EnsemblMetazoa; XM_024500048.1; XP_024345541.1; GeneID_36346514.
DR OrthoDB; 5481368at2759; -.
DR Proteomes; UP000019149; Unassembled WGS sequence.
DR InterPro; IPR036930; WGR_dom_sf.
DR InterPro; IPR008893; WGR_domain.
DR PANTHER; PTHR10459; DNA LIGASE; 1.
DR PANTHER; PTHR10459:SF60; POLY [ADP-RIBOSE] POLYMERASE 2; 1.
DR Pfam; PF05406; WGR; 1.
DR SUPFAM; SSF142921; WGR domain-like; 1.
PE 4: Predicted;
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Reference proteome {ECO:0000313|Proteomes:UP000019149};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 159..206
FT /note="WGR"
FT /evidence="ECO:0000259|Pfam:PF05406"
SQ SEQUENCE 301 AA; 33408 MW; 5E7D62AA9700E128 CRC64;
MDSLVPSGRV VPLDAVADNA PFSLTTGHPV SFPLLQPMPS LFLTVPSVPL KSTDIGGSRA
ECFVSLDAVI QHFYDLFFKK TADSWGTERA NFLKLHRRWK RRIEFETVTK GRGDGLQRLR
AKGDAAVNPT PRTVPPSLAP STVVHSPSSL AWLTSYSSNT RIIVLCAWSR TGTDIGYSRA
ECFVSLDAAI QHFHDLFLKK TADSWGIEAA DFVKLQRCIF LSNWNKLIPR EMGTVDDVTM
QIQEAYGVLT SKMLIEGPDT SRSINNTILF DAHILQGFGL KVLPLLDSLK VIKTKSRMLD
E
//
