ID W6UFA6_ECHGR Unreviewed; 2225 AA.
AC W6UFA6;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 28-JUN-2023, entry version 37.
DE SubName: Full=Nucleosome-remodeling factor subunit BPTF {ECO:0000313|EMBL:EUB59566.1};
GN ORFNames=EGR_05593 {ECO:0000313|EMBL:EUB59566.1};
OS Echinococcus granulosus (Hydatid tapeworm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC Eucestoda; Cyclophyllidea; Taeniidae; Echinococcus;
OC Echinococcus granulosus group.
OX NCBI_TaxID=6210 {ECO:0000313|EMBL:EUB59566.1, ECO:0000313|Proteomes:UP000019149};
RN [1] {ECO:0000313|EMBL:EUB59566.1, ECO:0000313|Proteomes:UP000019149}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24013640; DOI=10.1038/ng.2757;
RA Zheng H., Zhang W., Zhang L., Zhang Z., Li J., Lu G., Zhu Y., Wang Y.,
RA Huang Y., Liu J., Kang H., Chen J., Wang L., Chen A., Yu S., Gao Z.,
RA Jin L., Gu W., Wang Z., Zhao L., Shi B., Wen H., Lin R., Jones M.K.,
RA Brejova B., Vinar T., Zhao G., McManus D.P., Chen Z., Zhou Y., Wang S.;
RT "The genome of the hydatid tapeworm Echinococcus granulosus.";
RL Nat. Genet. 45:1168-1175(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EUB59566.1}.
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DR EMBL; APAU02000042; EUB59566.1; -; Genomic_DNA.
DR STRING; 6210.W6UFA6; -.
DR EnsemblMetazoa; XM_024494842.1; XP_024350762.1; GeneID_36341308.
DR OrthoDB; 2878869at2759; -.
DR Proteomes; UP000019149; Unassembled WGS sequence.
DR GO; GO:0016589; C:NURF complex; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR CDD; cd15532; PHD2_CHD_II; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR038028; BPTF.
DR InterPro; IPR018501; DDT_dom.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR45975; NUCLEOSOME-REMODELING FACTOR SUBUNIT BPTF; 1.
DR PANTHER; PTHR45975:SF2; NUCLEOSOME-REMODELING FACTOR SUBUNIT BPTF; 1.
DR Pfam; PF02791; DDT; 1.
DR Pfam; PF00628; PHD; 1.
DR SMART; SM00571; DDT; 1.
DR SMART; SM00249; PHD; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS50827; DDT; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS50016; ZF_PHD_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000019149};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 280..340
FT /note="DDT"
FT /evidence="ECO:0000259|PROSITE:PS50827"
FT DOMAIN 472..519
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 61..182
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 570..603
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 668..718
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1271..1457
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2093..2130
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2153..2195
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1208..1242
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1761..1795
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 61..87
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 88..102
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 128..171
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 573..589
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 668..713
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1323..1349
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1365..1382
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1417..1446
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2170..2195
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2225 AA; 243948 MW; 8275D23A8EDE5897 CRC64;
MGDSVNHPEG ISAPREGGHC QGSKKRPRLT FINPSEWVDL QPGCSVSTKK DADRNLCQRL
IDRQSKAKQE GVMRGRSEFE EPKPKKRQKQ QKSRRGRPRK RPIDPKRPWI ESDDEEGDYV
VPVDDESDDD AFLQRLAEEK EREEAEEIKK KQELQRQRRL KREERRSRAT GRPGRPRTQI
PFAHLYANSN DDAQSSSKPS ETSDGEQSLL NDYAVEEEVL DFPPPPAMEN DNFDEVGNGV
GTNLESTSVP DFPRFSPVVL RRRAPPLTLP PSSQDLICPP EHLLDALSIY QTLRRYGRLL
RLSPFQLEDF LSALLANENS NLIAAVHITL LNALITEDEA NGTHLCPPDC KDGVSLLSFI
IDRYTWPYFL SLYLSSVKRG ESAALAALAR VGNTATVASS GPIAAVTFSG GADAVVTSAL
FYPEDSVIPL DFSYPFVDLP QRLAVLRGLV GLFLATGPVR ADILREGFIA HDDFCRICRQ
SGEVLCCDTC PAVFHLTCLT PPLEAVPNSS WHCPLCETEQ EVYGERKVPK ARGETRISPL
GYDRAGRVYW YMEGRLFVEP VDFAQCEPEL PGLSEGVRDE EWERREAEQP TGDDEEEEAG
EGGEKIECGV EGACDPSVAY ANEPPVYYYS SLECITSVRQ RLSTQWEPAL CVQLDTVIAL
MEAKEQKSKQ AAMKSEPKES ESTKHENDCG EEKAEATESV VDVKKEEQDG DATELTKWPP
VLPLPSALTA AQLTALFSNS QSLHHIGSGG ETASSLMENA FVLELSGGVL VHNQDGLFEN
FPLPPDVHVQ RLSEPRPALV HSPLSSSVHL APSKRWRSWT NTLSQGLFVP NPTAETAELA
EVNIALNRPQ QHDEREKRRL LVNKFCLSDA ALEAWRWLDA EASAEMIRRA IGEESLDSAA
EADLVNRRAD AVGPLRWLHT MKLTLCFMEA QLPAAALCPV WRLLRKDWIA AVLKATSVHE
LADLLARLEA AIRPVAFQRT WTSSIGALQL DRFTSAQREE EKRIRALERS SAAVNAAPIT
LVRTKTIQPI RHTVWKTRGE EYRRLGGDGW QWVSATRRHQ KYLKTVTLQS AKPNIDRPAH
LGLGWGVKPE LLANTDLHPP LPEDAALDYR VHPITGVPLC QNVPRSVYTI PPEALRNQPD
GVINISQCLR IGGGDFFPPP ARSPLPLLPT SKTHQCGRAH FRLDSLLAMR EAAALRDQAA
SEVARGDLDQ LRMERETVAA RVADIQSRLS ELSSEAQIAR TEHARAVKSR QTAITEMKQL
SEQRLNQSCY QGTIPSTSSL RDGGGGGGGG RAKSRASMTP GRNRSVASRR LQREEYNYDS
GESAESEESA ATSSSRPASS TTGSNVLRRS SRRQKTKSVD PDFVVDFGED EEEEEEGRVD
IDRDDEDFSL RQCGSDDEAI DGSSWARGGG SVPQLDGAGD DDDDDGILEG DEGDEDEEDY
GVDENGTEND PEGKVDGLAQ KSPLRAAATG TVSATVSGKG ALIPPSSSPG KSLLALAIEG
KAPGITSNGE SPVEAKVVGS GADSGSGVTV VPTPIPTAPG GQPVRLVRVL RAPPGAPAGT
QIIQAVDPPS APTGASGTGN LIIPASTEPA LQKSLIQLSS SGGVIVTQAS TLPAGYRLIT
PSSLPLTTTN TVSSMTSGGG ASVVTSASRT PLNFVQVVST TPSSSSVQGL RPRPLVPQPL
RAGQPVTVSA TGAPSLISIA PSPVVRAPPL RPLLAPASRP ILASSSNLAP SLRPRMVRVV
TQPMQLDPSL DQAVTEAATK LHQVDLELFN LRKELRHLES QLAELSARVE EKEAMVARCG
RSTANPYSLS NHATSLLARL NRAAKAATAA NQRSKGRRFL TLPKHLPSVN PYAWPPDKLF
GSSVSSTYPE VDKDTSVPVT NLFRLSRVNL RALILAAGRK EVPGYEAEKK RLASIPWSYP
TARPCFAEAW RFRLRQILLQ PAASSCGILN TPSHYGVAMA TLAAHLRLLW HSLRWDEIIL
SAAACEDATL MADRYYLKQS ISEGHGGGYA LRRVVAIKPL LGRRMTEMVN EQREIELTKL
GQLAFYRCLR VKLELVLQLQ KATSLWLRYK RLQDKYWLRA NFLVETSVQK PAASKRIARG
NSHPSLGGNS DASTSRRSGR GSKRFADPDY DPAADEGWRV GIPCSNRRRR RTNYNEDRLM
EEDEAGEDVK TNEDQGVEDQ GDSSSSRRDA KKTEEWVSEE ALQLWEIRNF FDRQVVLNSP
SLFDS
//
