ID W6UID0_ECHGR Unreviewed; 1779 AA.
AC W6UID0;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Protein strawberry notch {ECO:0000313|EMBL:EUB60818.1};
GN ORFNames=EGR_04257 {ECO:0000313|EMBL:EUB60818.1};
OS Echinococcus granulosus (Hydatid tapeworm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC Eucestoda; Cyclophyllidea; Taeniidae; Echinococcus;
OC Echinococcus granulosus group.
OX NCBI_TaxID=6210 {ECO:0000313|EMBL:EUB60818.1, ECO:0000313|Proteomes:UP000019149};
RN [1] {ECO:0000313|EMBL:EUB60818.1, ECO:0000313|Proteomes:UP000019149}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24013640; DOI=10.1038/ng.2757;
RA Zheng H., Zhang W., Zhang L., Zhang Z., Li J., Lu G., Zhu Y., Wang Y.,
RA Huang Y., Liu J., Kang H., Chen J., Wang L., Chen A., Yu S., Gao Z.,
RA Jin L., Gu W., Wang Z., Zhao L., Shi B., Wen H., Lin R., Jones M.K.,
RA Brejova B., Vinar T., Zhao G., McManus D.P., Chen Z., Zhou Y., Wang S.;
RT "The genome of the hydatid tapeworm Echinococcus granulosus.";
RL Nat. Genet. 45:1168-1175(2013).
CC -!- SIMILARITY: Belongs to the SBNO family.
CC {ECO:0000256|ARBA:ARBA00006992}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EUB60818.1}.
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DR EMBL; APAU02000026; EUB60818.1; -; Genomic_DNA.
DR STRING; 6210.W6UID0; -.
DR EnsemblMetazoa; XM_024493506.1; XP_024352014.1; GeneID_36339972.
DR OMA; WMNSGDP; -.
DR OrthoDB; 3541637at2759; -.
DR Proteomes; UP000019149; Unassembled WGS sequence.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR GO; GO:0048583; P:regulation of response to stimulus; IEA:UniProt.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR026937; SBNO_Helicase_C_dom.
DR InterPro; IPR026741; SNO.
DR InterPro; IPR039187; SNO_AAA.
DR PANTHER; PTHR12706:SF30; PROTEIN STRAWBERRY NOTCH; 1.
DR PANTHER; PTHR12706; STRAWBERRY NOTCH-RELATED; 1.
DR Pfam; PF13872; AAA_34; 1.
DR Pfam; PF13871; Helicase_C_4; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000019149}.
FT DOMAIN 274..572
FT /note="Strawberry notch AAA"
FT /evidence="ECO:0000259|Pfam:PF13872"
FT DOMAIN 949..1240
FT /note="Strawberry notch helicase C"
FT /evidence="ECO:0000259|Pfam:PF13871"
FT REGION 761..822
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 834..860
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1624..1659
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1702..1746
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 786..800
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 804..822
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1624..1651
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1702..1737
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1779 AA; 196829 MW; 67E488E6654C876A CRC64;
MLFYPCLNAP RRFVERHIET VGFPAGRSGG VRKSVALIDH VVRTTVRSGV VKDMEPADAF
EIALQGLTAK DDSLSMPVTE QVSPDSAIVA DVKPAESDSN QEDYGLDIIS KALKSAGITP
SDVPNPVTTV APTQIYTVIN QTGNPLVQIP SVTNTQLRVP TISGVASRLI QLSKVSRAPT
IIRKRPSAEP ATFPPVKFIR RGDAPSSGPV KIETVSDMKF RTQTLGPQRI PMNYPLNFLS
QKRDEEIEED DSDDLAQAET YADYVPAKLH LGCRHPDPIV ESSTLSSVSP PDIHYNLRLP
REVIDSGRLS ALQLEAVVYA SQRHECILPN GQRAGFLIGD GAGVGKGRTI AAIIYENYMQ
HRKKAIWLSV SNDLRVDAER DLRDVGLTKL EVHSLNKFRY AKISGKVNGS VKKGVLFSTY
SSLIGESQGG AKAKYKTRLK QIVHWCGKDF DGVIVFDECH RAKNLTPSGS QKPTKTGLTV
LELQNRLPNA RIVYASATGA TEPRNMAYMT RLGLWGKGTP FKDFNSFIQF IERRGVGGME
LVAMDMKLRG MYIARQLSFH GVKFTIRPVE IEYVLLNGQS FVNVYNQSAD LWVCAYEYFS
EAARLINASD KYRKTMWGQF WSAHQRFFKY LCIAAKVDAC VELCKMALNA EKCVVIGLQS
TGEAKTLEQV EEFGTDLGEF VSTAKGVLQS LVERYFPTAS NLESFTARGE KLTIAGDRSS
STTLTRAGRA VAGGKGSGLG LKDILGEKAF AKLIAGGSLT GYDDDDSDRG NPGSVATGTK
KDDSDDAVSD EDDDNDDEWG NESDNQSKAN GGDSSSEYYD SDLEISNNCR GGVKRTKKSR
IGASSKRKQV YESDAAADSD DDDMDYDAMC DTFFARQRER AIRQNDSLWA DESTRNLSAK
YFLDSKSPDG MLASNGSVSL EEARKKCDGM KELLLGHIER IGRYLPPSSL DELIEKLGGP
SRVAEMTGRR GRVVMNDSGR ALYESRREGD CAMETINLME KQRFMDGEKL IAIVSEAASS
GISLQADRRA KNQRRRVHIT LELPWSADRA IQQFGRTHRS NQVSSPEYIF LISDLAGEQR
FASTVAKRLE SLGALTHGDR RATETRDLSR FNIDTKLGRE ALDIVLKTCI WGEEGIIKPP
ADYRSEDPIV ADAKTLEPLP PTLRPYHQFL SDVKSGLQGV GFLNGRTRDK DSRHMVKFLN
RILGLHVHTQ NAFFQYFSDT LEELVRRAKR GNRLDLGIMD LGTTGQNLEI VWTRKFDTRF
LSDSTQVCLH KVTTQRGVSW ASAMELYAQH DGDEDGFYLP KQSTVSRVMP LLAFCLRNKA
GDVGDRERRK MKRLYRVYRP NTGMQSEPME YGKLTEQYVK VSNPTDCQEH WSTIYDESAT
RCIHLIQRNH CNRVSVRNPQ GRSGICEVGL RERTYYVLSG SVMNVWTHVE RVLTNQAGNS
PPMQVVRLKP KDGKRIVGVL IPQDGVEAVL DCLNILQSNP DDIHLRPAPL PSGLSQPIHQ
VRSLSRSSLP PPIIKSTGQP PIVIGKPSVR FSVANATNTN AAAMTRNPVR NFGNATASTI
TTGVASSNAP TFLSPRMSFT ALHQPLSRFP LASRAQSRLE AAFQCQPISQ ARNIVPQRVF
TSINAPSSQQ SNSPQRFASP RGFQPSRPPS TRVTAPRAGR INWVSQDNGY YVNNLPVQGV
FQPRLQTQQQ LVQLQQVYQQ PQRQQPSQQK SRQLSQVPPT LVSAASPNNT ANPIGRTKSC
VPPNGASGRD PDRCICLNPC SFSLCPLPVC IPLLDEPPV
//
