ID W6UIX8_ECHGR Unreviewed; 380 AA.
AC W6UIX8;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Mechanosensory protein 2 {ECO:0000313|EMBL:EUB61111.1};
GN ORFNames=EGR_03959 {ECO:0000313|EMBL:EUB61111.1};
OS Echinococcus granulosus (Hydatid tapeworm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC Eucestoda; Cyclophyllidea; Taeniidae; Echinococcus;
OC Echinococcus granulosus group.
OX NCBI_TaxID=6210 {ECO:0000313|EMBL:EUB61111.1, ECO:0000313|Proteomes:UP000019149};
RN [1] {ECO:0000313|EMBL:EUB61111.1, ECO:0000313|Proteomes:UP000019149}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24013640; DOI=10.1038/ng.2757;
RA Zheng H., Zhang W., Zhang L., Zhang Z., Li J., Lu G., Zhu Y., Wang Y.,
RA Huang Y., Liu J., Kang H., Chen J., Wang L., Chen A., Yu S., Gao Z.,
RA Jin L., Gu W., Wang Z., Zhao L., Shi B., Wen H., Lin R., Jones M.K.,
RA Brejova B., Vinar T., Zhao G., McManus D.P., Chen Z., Zhou Y., Wang S.;
RT "The genome of the hydatid tapeworm Echinococcus granulosus.";
RL Nat. Genet. 45:1168-1175(2013).
CC -!- SIMILARITY: Belongs to the band 7/mec-2 family.
CC {ECO:0000256|ARBA:ARBA00008164}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EUB61111.1}.
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DR EMBL; APAU02000023; EUB61111.1; -; Genomic_DNA.
DR AlphaFoldDB; W6UIX8; -.
DR STRING; 6210.W6UIX8; -.
DR EnsemblMetazoa; XM_024493208.1; XP_024352307.1; GeneID_36339674.
DR OMA; VMCLKVI; -.
DR OrthoDB; 8291at2759; -.
DR Proteomes; UP000019149; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR Gene3D; 6.10.250.2090; -; 1.
DR Gene3D; 3.30.479.30; Band 7 domain; 1.
DR InterPro; IPR043202; Band-7_stomatin-like.
DR InterPro; IPR001107; Band_7.
DR InterPro; IPR036013; Band_7/SPFH_dom_sf.
DR InterPro; IPR001972; Stomatin_HflK_fam.
DR PANTHER; PTHR10264:SF19; AT06885P-RELATED; 1.
DR PANTHER; PTHR10264; BAND 7 PROTEIN-RELATED; 1.
DR Pfam; PF01145; Band_7; 1.
DR PRINTS; PR00721; STOMATIN.
DR SMART; SM00244; PHB; 1.
DR SUPFAM; SSF117892; Band 7/SPFH domain; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000019149};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 87..109
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 103..262
FT /note="Band 7"
FT /evidence="ECO:0000259|SMART:SM00244"
FT REGION 1..36
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 53..74
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 339..380
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 58..74
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 364..380
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 380 AA; 40792 MW; 9067E1F37AD628B3 CRC64;
MPSVSFASDP ANRGGGSGGG GNGEGGGGGE EAQLRVPQMP QIARGFSLVP ERLGSKGNNP
GGGSSSNPSK QRQGNKGMFG CEAAIRILAY FAVLVTLPFS LVMCLKVIAQ YERAVVFRLG
RLVSEIPKGP GLVFILPCLD NVKTIDLRTF TFNVPTQEVL TKDSVTVAVD AVVYYRIFDP
VMSVVNVEDA NRSTRLLAQT TLRNVLGTVD LYQLLTAREQ IAHLMQDCLD TATETWGVKV
ERVDIKDVRL PIQLQRAMAA EAEAAREAKA KVIAAEGEQR ASVALKAAAM EIGECPIALQ
LRYLQTLSSI SDEKNSTIIF PLPIDLLSLF HQAYTSNLSS AGHPPSEGTL HSEDLPPPPP
QRASVVHQKS TTDTLEEALI
//
