ID W6UNR9_ECHGR Unreviewed; 783 AA.
AC W6UNR9;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Protocadherin-11 X-linked {ECO:0000313|EMBL:EUB63310.1};
GN ORFNames=EGR_01801 {ECO:0000313|EMBL:EUB63310.1};
OS Echinococcus granulosus (Hydatid tapeworm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC Eucestoda; Cyclophyllidea; Taeniidae; Echinococcus;
OC Echinococcus granulosus group.
OX NCBI_TaxID=6210 {ECO:0000313|EMBL:EUB63310.1, ECO:0000313|Proteomes:UP000019149};
RN [1] {ECO:0000313|EMBL:EUB63310.1, ECO:0000313|Proteomes:UP000019149}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24013640; DOI=10.1038/ng.2757;
RA Zheng H., Zhang W., Zhang L., Zhang Z., Li J., Lu G., Zhu Y., Wang Y.,
RA Huang Y., Liu J., Kang H., Chen J., Wang L., Chen A., Yu S., Gao Z.,
RA Jin L., Gu W., Wang Z., Zhao L., Shi B., Wen H., Lin R., Jones M.K.,
RA Brejova B., Vinar T., Zhao G., McManus D.P., Chen Z., Zhou Y., Wang S.;
RT "The genome of the hydatid tapeworm Echinococcus granulosus.";
RL Nat. Genet. 45:1168-1175(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EUB63310.1}.
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DR EMBL; APAU02000007; EUB63310.1; -; Genomic_DNA.
DR AlphaFoldDB; W6UNR9; -.
DR STRING; 6210.W6UNR9; -.
DR EnsemblMetazoa; XM_024491050.1; XP_024354506.1; GeneID_36337516.
DR OrthoDB; 5359772at2759; -.
DR Proteomes; UP000019149; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR CDD; cd11304; Cadherin_repeat; 4.
DR Gene3D; 2.60.40.60; Cadherins; 6.
DR InterPro; IPR002126; Cadherin-like_dom.
DR InterPro; IPR015919; Cadherin-like_sf.
DR InterPro; IPR020894; Cadherin_CS.
DR InterPro; IPR013164; Cadherin_N.
DR PANTHER; PTHR24028; CADHERIN-87A; 1.
DR PANTHER; PTHR24028:SF310; STARRY NIGHT; 1.
DR Pfam; PF00028; Cadherin; 1.
DR Pfam; PF08266; Cadherin_2; 1.
DR PRINTS; PR00205; CADHERIN.
DR SMART; SM00112; CA; 4.
DR SUPFAM; SSF49313; Cadherin-like; 4.
DR PROSITE; PS00232; CADHERIN_1; 1.
DR PROSITE; PS50268; CADHERIN_2; 6.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW ProRule:PRU00043}; Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Membrane {ECO:0000256|ARBA:ARBA00022989};
KW Reference proteome {ECO:0000313|Proteomes:UP000019149};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..783
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004882324"
FT DOMAIN 31..160
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 166..301
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 331..458
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 460..586
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 596..703
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 703..765
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT REGION 752..783
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 783 AA; 87436 MW; BDC865E26B37F5D7 CRC64;
MYTFPWILLF TKFLLPFSYA LSKDHALNLP DTVVIEEKLL EELPSGHIIL NLNKVVTLHD
TRHNASQHRF ASESRIFTLI PAEQHEYFRV SPNHDLVVVK RIDRETICGT VEQDECLLRL
QFNALQMVDH NSRTLLRTVF VRFLLVDTND NRPICQPPST ALKDDQHSIP TIEVSEDAHL
NEVLASWTVI DADTPKHGIY GFRQLSTSPI DYAGDQFSLD LSEATLTQRP WSKVTLQLRL
NRPFKKQPSM NSRSSRLLGE YLIKYAVWDS SDEPSDYSSS HRTVCHLRVH VLDINNHHPE
WISPQEFKFN QPVRVDLKEG TVGSMGRNNH ILKLEATDGD IGPNARIQYH MMMDTDKSLE
VESLLNNLLH LDPRTGVLRL RRYPIDYEAI SRQLPLKQVS SNGNEGAGIR FFVKAVDSPK
DESQQRSSSV GEVVLYIHDI NDAHPKITVL PISLMPSFSP GGKKTLSVRE NLPALEPVAT
VSVEDPDTGS GGRVECDLIE VSLKNGSTPN FRLIKTTFPE WTTKQSNMGY QILTAGPLDR
EAQSSHDLRL ICIDSEGATD PNEVRLTSVV NIFVRVLDEN DCSPTASPIE NEFLSDGTTV
ACKVVENVNQ GMKICQIKAV DSDEGENAMV EWTAGNDMPS WLKVDADSGW LVASGPGGPD
REMAERHNFS VIATDGRRGK TRLSTTVAVS LEVTDVNDHA PEIGSFFYFA ISESAPPGTF
IGRLNATDRD KTGTDNAALT YTIARMRPYD PNRISSSEVD EKPGVWSYPN AGSQKSKIPV
VVS
//
