ID W6URP5_ECHGR Unreviewed; 1522 AA.
AC W6URP5;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=U5 small nuclear ribonucleoprotein {ECO:0000313|EMBL:EUB63918.1};
GN ORFNames=EGR_01046 {ECO:0000313|EMBL:EUB63918.1};
OS Echinococcus granulosus (Hydatid tapeworm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC Eucestoda; Cyclophyllidea; Taeniidae; Echinococcus;
OC Echinococcus granulosus group.
OX NCBI_TaxID=6210 {ECO:0000313|EMBL:EUB63918.1, ECO:0000313|Proteomes:UP000019149};
RN [1] {ECO:0000313|EMBL:EUB63918.1, ECO:0000313|Proteomes:UP000019149}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24013640; DOI=10.1038/ng.2757;
RA Zheng H., Zhang W., Zhang L., Zhang Z., Li J., Lu G., Zhu Y., Wang Y.,
RA Huang Y., Liu J., Kang H., Chen J., Wang L., Chen A., Yu S., Gao Z.,
RA Jin L., Gu W., Wang Z., Zhao L., Shi B., Wen H., Lin R., Jones M.K.,
RA Brejova B., Vinar T., Zhao G., McManus D.P., Chen Z., Zhou Y., Wang S.;
RT "The genome of the hydatid tapeworm Echinococcus granulosus.";
RL Nat. Genet. 45:1168-1175(2013).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EUB63918.1}.
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DR EMBL; APAU02000004; EUB63918.1; -; Genomic_DNA.
DR STRING; 6210.W6URP5; -.
DR EnsemblMetazoa; XM_024490295.1; XP_024355114.1; GeneID_36336761.
DR OrthoDB; 5476798at2759; -.
DR Proteomes; UP000019149; Unassembled WGS sequence.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
DR GO; GO:0036211; P:protein modification process; IEA:InterPro.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR004344; TTL/TTLL_fam.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR44006; U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 40 KDA PROTEIN; 1.
DR PANTHER; PTHR44006:SF1; U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 40 KDA PROTEIN; 1.
DR Pfam; PF03133; TTL; 1.
DR Pfam; PF00400; WD40; 7.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS51221; TTL; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 2.
DR PROSITE; PS50082; WD_REPEATS_2; 6.
DR PROSITE; PS50294; WD_REPEATS_REGION; 4.
PE 4: Predicted;
KW mRNA processing {ECO:0000256|ARBA:ARBA00023187};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000019149};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Ribonucleoprotein {ECO:0000313|EMBL:EUB63918.1};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 885..918
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 929..970
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 971..1013
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1020..1054
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1055..1089
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1116..1146
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 527..586
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 649..673
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 712..737
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1188..1219
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1473..1506
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1195..1215
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1480..1506
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1522 AA; 171717 MW; 4B41D39EA2D6EAA6 CRC64;
MGQTSAKRIQ NHISAMEGAG YTVDEKLATK LRNSLTKLNI MSDDDGQLMC ILPVPNDILD
SDQGIKKEIQ QQLSLPRPKF FLNCYNGSHI WTETVMQLNY QVFRECEQMA NHIPNCGLFT
NKLGLLMSLR NYADDCKRNS RKDVSVNFIP ETYWIDDAKE KAEFINKLSD HQIWLMKPCG
LNQGKGICLI RSQQDFVRLE EARSEEVRRN PQMCRPRIVQ KYLTTPLLLN NRKFDIRCYF
MLASTMPYLV LFTPGYIRLS LRKYDPADTN LVTHLTNQFI QKRDPSYDRS KDDSVWTFRR
LNEYINTNVA PNKHLQKNWV TRHMLPEMHR ITMHVFNAVK DKLACRIGFF EIYGMDFMID
DNMKIWLIEI NSNPAMNTNC EVLRQVIPPV VNRFIQISIE CFEKARRWQP LLPILGILPR
NPSELGEERD SYTWNVSLRP PPKYITNGGL PASFTILFNE SLTAAKSRQS RCYSTPLRLW
VPPKMYLTAH LPKPGLVIRR SPSPPSHSSA SLPRISAIPH KYSALATMTS KPSPPRTDYQ
KPPAYSPREM RFFRSPSHRV TSGSESSRHS TERESIPTQN LQESPLGLQR VSDLGANQSI
TSDKADVPNV VAVAEEPLAQ EQVHKLPDPQ KELGKLSDEY LVVAPDGNFG ANGKHQMDPK
RQEVTGTQSR GSDESNTLLR LIQDGAFKWT KRGTVGRDSP AGVEMPIEDD VVTSNNSSSV
STHATPRRRK LKKNRNDSCS VRIPPLMPEY VLMPISPVIM PPLPPLVLGA TLPTEMPNEE
PEENATNNGN ELIDLSNMSA KFRIPVVGQS APWHRLRCGK MAMDLKRSFP AMSMVPVPNK
RTRTEDARAI VSNQILKSAQ GQIIPAGMPG SMRRTSSILS PNMLLTGHES EVFCVKFVPT
EGSYLVSAGF DRQIFVWETY GQCDNVAVMA GHGGAILNLA LSSDGELLYS ASSDKTVAIW
DLNTCQRIKK IRGHQNIVNS VDIARRGPQV IVSGSDDGTV RLWDRRQKTE VQNFQNTYQV
LAVAFSDTAE MIFSGGIDNI IKGWDLRKLD VAMRLTGHTD TVTGLALSPD GDFLLSNAMD
NTLRVWDVRP YAPAERCTKI LQGHVHTFEK NLLRCAWSPD GQYVTCGSGD RYVHVWEVKT
RNLIYKLPGH SASVNETDFH PLEPILLSGG GDKKIFLGEI ELGYKRDQSR SRSLTRRQLR
TSTSKKGSAT RSRLSSRSKT ARKLIDLNKR ANKYQANIDQ YIELLQHASL WFDRNLEEIW
NMICIVNSDE AETITYDSFK AILMDVKAPL NDVEIHLLTM ILDPNTEGSI QIKKFADGIL
GLCKEEEMKA LKACPSPLIK PITRWVRVHF RNATLASISH HPLHFDEDVP TSYTIDLLVD
VIRRRNHIYA PSIKLFRKQE PLPPEEIQQV GTSLEQLGIK GGTRLSPMEA TILYQTQYSI
NLPRANLFVT SIDDSYLLWD EAALWLEDVD LKGPGVPSEK SRSTVESVPP TESTISSESD
SSSVGSLASF LTVEKASKSF KL
//
