ID W6UVT6_ECHGR Unreviewed; 607 AA.
AC W6UVT6;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=Coatomer subunit epsilon {ECO:0000256|ARBA:ARBA00015828};
DE AltName: Full=Epsilon-coat protein {ECO:0000256|ARBA:ARBA00031602};
GN ORFNames=EGR_02639 {ECO:0000313|EMBL:EUB62507.1};
OS Echinococcus granulosus (Hydatid tapeworm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC Eucestoda; Cyclophyllidea; Taeniidae; Echinococcus;
OC Echinococcus granulosus group.
OX NCBI_TaxID=6210 {ECO:0000313|EMBL:EUB62507.1, ECO:0000313|Proteomes:UP000019149};
RN [1] {ECO:0000313|EMBL:EUB62507.1, ECO:0000313|Proteomes:UP000019149}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24013640; DOI=10.1038/ng.2757;
RA Zheng H., Zhang W., Zhang L., Zhang Z., Li J., Lu G., Zhu Y., Wang Y.,
RA Huang Y., Liu J., Kang H., Chen J., Wang L., Chen A., Yu S., Gao Z.,
RA Jin L., Gu W., Wang Z., Zhao L., Shi B., Wen H., Lin R., Jones M.K.,
RA Brejova B., Vinar T., Zhao G., McManus D.P., Chen Z., Zhou Y., Wang S.;
RT "The genome of the hydatid tapeworm Echinococcus granulosus.";
RL Nat. Genet. 45:1168-1175(2013).
CC -!- SUBUNIT: Oligomeric complex that consists of at least the alpha, beta,
CC beta', gamma, delta, epsilon and zeta subunits.
CC {ECO:0000256|ARBA:ARBA00011775}.
CC -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, COPI-coated vesicle membrane
CC {ECO:0000256|ARBA:ARBA00004347}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004347}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004347}. Golgi apparatus membrane
CC {ECO:0000256|ARBA:ARBA00004255}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004255}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004255}. Membrane
CC {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004287}.
CC -!- SIMILARITY: Belongs to the COPE family.
CC {ECO:0000256|ARBA:ARBA00008827}.
CC -!- SIMILARITY: Belongs to the heat shock protein 70 family.
CC {ECO:0000256|ARBA:ARBA00007381}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EUB62507.1}.
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DR EMBL; APAU02000012; EUB62507.1; -; Genomic_DNA.
DR AlphaFoldDB; W6UVT6; -.
DR STRING; 6210.W6UVT6; -.
DR EnsemblMetazoa; XM_024491888.1; XP_024353703.1; GeneID_36338354.
DR OrthoDB; 6256at2759; -.
DR Proteomes; UP000019149; Unassembled WGS sequence.
DR GO; GO:0030663; C:COPI-coated vesicle membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR GO; GO:0006890; P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum; IEA:InterPro.
DR Gene3D; 3.30.30.30; -; 1.
DR Gene3D; 3.30.420.40; -; 2.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR006822; Coatomer_esu.
DR InterPro; IPR013126; Hsp_70_fam.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR10805; COATOMER SUBUNIT EPSILON; 1.
DR PANTHER; PTHR10805:SF0; COATOMER SUBUNIT EPSILON; 1.
DR Pfam; PF04733; Coatomer_E; 1.
DR Pfam; PF00012; HSP70; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000019149};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 314..337
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 385..406
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 607 AA; 67962 MW; A0DCC9BE9FD11CCC CRC64;
MNTESVIQDA RENFILENFQ ECLKLLHGIP IVSPEFRDEI DLLTFQAYIA QQKYNVVINE
VSESHERPEY RLVLLLSKQL SGAYTKEEIV DKLNAMLMEN ISAKDPTALL IGATIFMNLN
MPEKALRVLH QSSDLMCDAM SVHCLLMMNR ADLAEKIVLR MQSKNEDSMV CQLASAELYL
VQGGEKVTEA LNIYQELQEK NKPSTLLLNG QAIALVALGR HAEAEPLLRQ ALDIDPSHSA
SLLNMISVSV NTGKPIESLN RYISQVRDCD KSHSFLESLD KMLRSFRTTC LTNSRSPLRL
LFPANFTHSS SVPLIMVLFC ATLVEYLFLC FLPLYLFGNT EVKGLALHTI SRQEAVYHTY
MKMVTEYAKG AQSIKAAGCI VSESGYCFMF HFDMSFVISL CLLFALPFCN GISTMAIDLG
TDVTKVAVVR ATRDPTIVFA ELPSIVGKTL DHPTVIEYQK RYPYHNLTFS YESRQLAFVV
NGKEFTVETL LAMFLEYVKK TAEAFAESQM KTAVITVPSY FTQAERRAVL RSAGLANIEV
IQLMDDNVAV ALDYIRPRIK LAKEKPIYLF FDVGATATTA TLVSYQMAQV KGESSGEHPH
VYVLGAA
//
