ID W6UXJ0_ECHGR Unreviewed; 179 AA.
AC W6UXJ0;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=E3 ubiquitin-protein ligase 8-Mar {ECO:0000313|EMBL:EUB58274.1};
GN ORFNames=EGR_06909 {ECO:0000313|EMBL:EUB58274.1};
OS Echinococcus granulosus (Hydatid tapeworm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC Eucestoda; Cyclophyllidea; Taeniidae; Echinococcus;
OC Echinococcus granulosus group.
OX NCBI_TaxID=6210 {ECO:0000313|EMBL:EUB58274.1, ECO:0000313|Proteomes:UP000019149};
RN [1] {ECO:0000313|EMBL:EUB58274.1, ECO:0000313|Proteomes:UP000019149}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24013640; DOI=10.1038/ng.2757;
RA Zheng H., Zhang W., Zhang L., Zhang Z., Li J., Lu G., Zhu Y., Wang Y.,
RA Huang Y., Liu J., Kang H., Chen J., Wang L., Chen A., Yu S., Gao Z.,
RA Jin L., Gu W., Wang Z., Zhao L., Shi B., Wen H., Lin R., Jones M.K.,
RA Brejova B., Vinar T., Zhao G., McManus D.P., Chen Z., Zhou Y., Wang S.;
RT "The genome of the hydatid tapeworm Echinococcus granulosus.";
RL Nat. Genet. 45:1168-1175(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EUB58274.1}.
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DR EMBL; APAU02000065; EUB58274.1; -; Genomic_DNA.
DR AlphaFoldDB; W6UXJ0; -.
DR STRING; 6210.W6UXJ0; -.
DR EnsemblMetazoa; XM_024496158.1; XP_024349470.1; GeneID_36342624.
DR OMA; YVYVVQE; -.
DR OrthoDB; 1342875at2759; -.
DR Proteomes; UP000019149; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR011016; Znf_RING-CH.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR46065; E3 UBIQUITIN-PROTEIN LIGASE MARCH 2/3 FAMILY MEMBER; 1.
DR PANTHER; PTHR46065:SF3; FI20425P1; 1.
DR Pfam; PF12906; RINGv; 1.
DR SMART; SM00744; RINGv; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS51292; ZF_RING_CH; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000019149};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 99..117
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 129..147
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 21..90
FT /note="RING-CH-type"
FT /evidence="ECO:0000259|PROSITE:PS51292"
SQ SEQUENCE 179 AA; 21018 MW; 3208F41ACB7B5CDB CRC64;
MGRQWCTKDV EEMEASGKHK CNCHDIPFCR ICYDSNDESN DMEMESRGRL IAPCLCDGSM
KYVHQCCIQR WIKISRSRKC ELCNFRYAIR RHVKENKGWK FYAFEIIILL LAAWLSWHSA
VAFTSTSSGL LQASFFAGLM GLILAWCKFR KGSDRSEYVY VVQEPSNRRM RKLRRNTMT
//
