ID   W6YWZ6_COCMI            Unreviewed;      1396 AA.
AC   W6YWZ6;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   RecName: Full=5-oxoprolinase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=COCMIDRAFT_8295 {ECO:0000313|EMBL:EUC42065.1};
OS   Bipolaris oryzae ATCC 44560.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Pleosporomycetidae; Pleosporales; Pleosporineae; Pleosporaceae; Bipolaris.
OX   NCBI_TaxID=930090 {ECO:0000313|EMBL:EUC42065.1};
RN   [1] {ECO:0000313|EMBL:EUC42065.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 44560 {ECO:0000313|EMBL:EUC42065.1};
RX   PubMed=23357949; DOI=10.1371/journal.pgen.1003233;
RA   Condon B.J., Leng Y., Wu D., Bushley K.E., Ohm R.A., Otillar R., Martin J.,
RA   Schackwitz W., Grimwood J., MohdZainudin N., Xue C., Wang R., Manning V.A.,
RA   Dhillon B., Tu Z.J., Steffenson B.J., Salamov A., Sun H., Lowry S.,
RA   LaButti K., Han J., Copeland A., Lindquist E., Barry K., Schmutz J.,
RA   Baker S.E., Ciuffetti L.M., Grigoriev I.V., Zhong S., Turgeon B.G.;
RT   "Comparative genome structure, secondary metabolite, and effector coding
RT   capacity across Cochliobolus pathogens.";
RL   PLoS Genet. 9:E1003233-E1003233(2013).
CC   -!- SIMILARITY: Belongs to the oxoprolinase family.
CC       {ECO:0000256|ARBA:ARBA00010403}.
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DR   EMBL; KI964074; EUC42065.1; -; Genomic_DNA.
DR   RefSeq; XP_007691400.1; XM_007693210.1.
DR   STRING; 930090.W6YWZ6; -.
DR   GeneID; 19126158; -.
DR   KEGG; bor:COCMIDRAFT_8295; -.
DR   eggNOG; KOG1939; Eukaryota.
DR   HOGENOM; CLU_002157_0_1_1; -.
DR   OrthoDB; 674at2759; -.
DR   Proteomes; UP000054032; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   InterPro; IPR049517; ACX-like_C.
DR   InterPro; IPR008040; Hydant_A_N.
DR   InterPro; IPR002821; Hydantoinase_A.
DR   InterPro; IPR003692; Hydantoinase_B.
DR   InterPro; IPR045079; Oxoprolinase_fam.
DR   PANTHER; PTHR11365:SF2; 5-OXOPROLINASE; 1.
DR   PANTHER; PTHR11365; 5-OXOPROLINASE RELATED; 1.
DR   Pfam; PF19278; Hydant_A_C; 1.
DR   Pfam; PF05378; Hydant_A_N; 1.
DR   Pfam; PF01968; Hydantoinase_A; 1.
DR   Pfam; PF02538; Hydantoinase_B; 1.
PE   3: Inferred from homology;
FT   DOMAIN          12..234
FT                   /note="Hydantoinase/oxoprolinase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05378"
FT   DOMAIN          253..563
FT                   /note="Hydantoinase A/oxoprolinase"
FT                   /evidence="ECO:0000259|Pfam:PF01968"
FT   DOMAIN          574..761
FT                   /note="Acetophenone carboxylase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF19278"
FT   DOMAIN          782..1363
FT                   /note="Hydantoinase B/oxoprolinase"
FT                   /evidence="ECO:0000259|Pfam:PF02538"
FT   REGION          1289..1325
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1346..1396
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1365..1381
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1396 AA;  151996 MW;  577C7796A64C6875 CRC64;
     MAAPKIAQRG IRIAIDRGGT FTDCVGNPGT GKMEDDVLIK LLSVDPSNYD DAPLEGIRRL
     LSKFTGTEIP RGQPLDTSKI ESIRMGTTVA TNALLERKGE DIAMVVTKGF KDCLEIGNQS
     RPNIFALDIR KPEVLYKKVV EIDERVTLED YAEDPERNQT QAASIEEAGD GAELVKGLSG
     ETVRILQRPQ EEAIRKQLQE VYDSGLKSIA VCLMHGYTYP KHEALVGKIA REIGFEHVSL
     SHELMPMIKL VPRATSACAD AYLTPAIRKY IDGFSKGFEG GLGTKSVKRE EGSKGARCEF
     MQSDGGLVDV DMFSGLKAIL SGPAGGVVGY ALTSYDPQTK IPVIGFDMGG TSTDVSRYGA
     GRYDHVFETT TAGVTIQSPQ LDINTVAAGG GSRLFWKNGL FVVGPESASA HPGPACYRKG
     GPLTITDANL FLGRLLPDFF PKIFGKNEDE GLDAQASEKL FKELADQINK EIAGGNKEKE
     MSLDDIANGF IKIANETMTR PIRSLTEARG HDTSKHRLAT FGGAGGQHAV AIAEALGISQ
     ILVHRYSSVL SAYGMALADV VDERQEPESK VWSDKKDVRE YLQAKMADLK SKSTATLKEQ
     GFDEEHIQFE EYLNLRYRGT ESALMIIKPT KEEAQQEYDG DEWAFGKAFV KQHEQEFGFT
     LPDRDIIVDD VRARGIGKSF EGLEKSVDQQ LKEIKPKDLQ GDAKRYDTRK VFFEGGRQDT
     SVYKLEDLEV GDRLKGPAII ADGTQTIVVT PGATALIINT HVVINIGETE DQEKQIDTKE
     VDPILLSIFA HRFMAIAEQM GRALQKTSVS TNVKERLDYS CALFDADGGL VANAPHLPVH
     LGSMSTCVRK QAAIWKGKLK KGDVLVSNHP MFGGTHLPDI TVITPAFSGD NIVFYVASRA
     HHADIGGILP GSMPPASKEL YQEGAAIKSE KLVSEGHFNE ERITELLLDE PGQYPGCSGT
     RCLSDNINDL KAQVAANQKG INLISTLMSD YGEEVVKFYM TSIQANAEKS VRALLKDVYK
     RFEGQDLSAE EFMDDGSPIR LKISIDPEKG EAVFDFSGTG PEVYGNINAP EAVTYSAIIY
     CLRCLISEDI PLNQGCLKPI HVLIPKKSFL SPSDNAAVVG GNVLTSQRVT DVVLKAFRAC
     AASQGDCNNL TFGFGGTTFG EGAKSGERKE TKGFGYYETI AGGSGAGPTW NGTSGVHTHM
     TNTRITDSEV FERRYPVLLR EFSLRQGSAG RGMHIGGEGV IRDIEFRIPV QVSILSERRV
     YHPYGMEGGG DAACGLNIWV RKVDKKAIDQ NSDSKKPTEP QESAPHAPTT SSDVEALEKK
     DAASDKKEDV EYRYINLGAK NTASMRPGER IIIHTPGGGG WGKEGEESRL QDKKDPKEIW
     KGGSVAGRQS TAEASA
//