ID W6Z352_COCMI Unreviewed; 1513 AA.
AC W6Z352;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=SPX domain-containing protein {ECO:0000259|PROSITE:PS51382};
GN ORFNames=COCMIDRAFT_98951 {ECO:0000313|EMBL:EUC44153.1};
OS Bipolaris oryzae ATCC 44560.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Pleosporaceae; Bipolaris.
OX NCBI_TaxID=930090 {ECO:0000313|EMBL:EUC44153.1};
RN [1] {ECO:0000313|EMBL:EUC44153.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 44560 {ECO:0000313|EMBL:EUC44153.1};
RX PubMed=23357949; DOI=10.1371/journal.pgen.1003233;
RA Condon B.J., Leng Y., Wu D., Bushley K.E., Ohm R.A., Otillar R., Martin J.,
RA Schackwitz W., Grimwood J., MohdZainudin N., Xue C., Wang R., Manning V.A.,
RA Dhillon B., Tu Z.J., Steffenson B.J., Salamov A., Sun H., Lowry S.,
RA LaButti K., Han J., Copeland A., Lindquist E., Barry K., Schmutz J.,
RA Baker S.E., Ciuffetti L.M., Grigoriev I.V., Zhong S., Turgeon B.G.;
RT "Comparative genome structure, secondary metabolite, and effector coding
RT capacity across Cochliobolus pathogens.";
RL PLoS Genet. 9:E1003233-E1003233(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Vacuole membrane
CC {ECO:0000256|ARBA:ARBA00004128}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004128}.
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DR EMBL; KI964010; EUC44153.1; -; Genomic_DNA.
DR RefSeq; XP_007689326.1; XM_007691136.1.
DR STRING; 930090.W6Z352; -.
DR GeneID; 19129364; -.
DR KEGG; bor:COCMIDRAFT_98951; -.
DR eggNOG; KOG1161; Eukaryota.
DR eggNOG; KOG4580; Eukaryota.
DR HOGENOM; CLU_249242_0_0_1; -.
DR OrthoDB; 11387at2759; -.
DR Proteomes; UP000054032; Unassembled WGS sequence.
DR GO; GO:0000776; C:kinetochore; IEA:InterPro.
DR GO; GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0034508; P:centromere complex assembly; IEA:InterPro.
DR CDD; cd22647; CTF3_NTD_HEAT; 1.
DR CDD; cd07892; PolyPPase_VTC2-3_like; 1.
DR CDD; cd14480; SPX_VTC2_like; 1.
DR Gene3D; 3.20.100.30; VTC, catalytic tunnel domain; 1.
DR InterPro; IPR012485; CENP-I.
DR InterPro; IPR003807; DUF202.
DR InterPro; IPR004331; SPX_dom.
DR InterPro; IPR018966; VTC_domain.
DR InterPro; IPR042267; VTC_sf.
DR PANTHER; PTHR46140; VACUOLAR TRANSPORTER CHAPERONE 1-RELATED; 1.
DR PANTHER; PTHR46140:SF2; VACUOLAR TRANSPORTER CHAPERONE 2-RELATED; 1.
DR Pfam; PF07778; CENP-I; 1.
DR Pfam; PF02656; DUF202; 1.
DR Pfam; PF09359; VTC; 1.
DR PROSITE; PS51382; SPX; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Vacuole {ECO:0000256|ARBA:ARBA00022554}.
FT TRANSMEM 1397..1415
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1422..1442
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1462..1482
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 702..877
FT /note="SPX"
FT /evidence="ECO:0000259|PROSITE:PS51382"
FT REGION 788..823
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1261..1333
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 808..823
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1268..1282
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1292..1313
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1513 AA; 169915 MW; 0107A0FFCD00B2CF CRC64;
MHAGTDSGMP SVAEERPTLQ ETLNLLHQAS RTSAKQRTIK VSSIVDVICR YATEGGLDQD
ALRDVVQLIS VKTLLDQTTI TTLIKNLYPA RRIPRDVVIT VVGALGQGKG KPSPGTQDSL
VKWLITVHEI IEEQSVLSRL YGVLFGMLDM ISISRTSLCH LLSLITRRKH VKPFRIQQLL
ELSRGLGNEP ALQGLLRVYK DYYPDIILGS TSTSRKSFAP RPDDEWRSRI AAVHEASNAV
DDSGGEVQNG FKVLRKGPRG SKSSAIPEVH TYHATENSVT LEGIDSVDDF VEKLDRIEPP
GQLVSLLTDP LLQKYVDLKP SHISTARIGV WLAACLEEQF EAHRQRAGDD EYLDEILGGL
LRYAQYTKTL HPSALAFFRE YLPVWNGQDN FDTILGLLSH IDIQSFEEVH AAYLSFVERA
IAAQGIPAYP KLINFYTALL QHHMSKAVTD AANRGSESTQ TLSRVTTHVA TLFTSALVSI
PAGLGSDVTS CILSFYELVS TSSKPRVVPI QLPPMHLIYL LTQDASATTF ARVCGIVGAY
KLAFDRHPKP VKAYYPVEAT DTFNYCLRDM YNLLWVARGL VAQDKKSQGL FCDAALRSML
HSYLKKMDRE HTIETAFGLS HNAWLAALSA AAWRAMEQDF ADKNGLDPNT MVHHRGPVSE
KSLEALKRKG GVSVDWDGGS GYKAWVLQWL DERGLGASRL AMKFGTTLRR SVYAPWKDQY
IDYDKLKKLL KDNEDDDSWT ADDESAFVDE LANVQLEKVH NFITDISQKL RDRTSACEKK
LEPLAVGIHD DDNTNASGNG EGEGLLAESS KDAPKKPELS QEEREKLLKE VLRELDSITK
ETKELEAFSR INFTAVIKAT KKHDKLRGSS YRLRPFIDAR IARHPLHTED ASPLLYRLSA
LYSFVRQSLD GKSKEALSFN DDSVTGETFN SHKFWVHMDN LFEVKTVILR RLPVLVYNPQ
TSKVAEGTQR DPTITSIYFD NPDFSLYTDK VNGKPDASSL RLRWYGQLNE KPEIMFEKKV
IKEGNAAEEV RFPIKAKYVQ PFLEDKYHME KSIEKMEYRP NKDQQKLDKF KSAVSDIQGF
VKEQKLQPML RANYTRTAFQ IPGDDRIRIS LDTNLALIRE DSLDESRPCR DPDDWHRHDI
DGAQLEYPFK NLKKGEVHRF PYALLEIKVK GSQKYEWIED LMHSHLVKES PRFSKFVHGV
AKLFEDNVNT FPFWLSEVDN DIRKEPEKAF DDEQEKKRKA AEDEFAVGSL FGARASPSFR
PSIASPVGSP AATRSVPKSA SMAAHSQPAV RPSLPTIGSH LSQSQQDRNR DANNNTNVRA
EEDSDSDDDV VAGGKTQRGG LAALFPSFST SKYARRQQRK IQLPPGIRDP GVWIKDQGPV
KVEAKVWLAN QRTFIKWQHV SVLLASLSLG LYNAAGEGND IARVLAVVYT CVAAFTLAWG
YGMYVYRAKL IRERSGKDFD AITGPLVVCI GLAVALCLNF GFKYNALIKQ GHHDHTHHHA
NATSVNEQME LRI
//
