ID W6Z9A3_COCMI Unreviewed; 552 AA.
AC W6Z9A3;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=Amidase domain-containing protein {ECO:0000259|Pfam:PF01425};
GN ORFNames=COCMIDRAFT_37950 {ECO:0000313|EMBL:EUC44139.1};
OS Bipolaris oryzae ATCC 44560.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Pleosporaceae; Bipolaris.
OX NCBI_TaxID=930090 {ECO:0000313|EMBL:EUC44139.1};
RN [1] {ECO:0000313|EMBL:EUC44139.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 44560 {ECO:0000313|EMBL:EUC44139.1};
RX PubMed=23357949; DOI=10.1371/journal.pgen.1003233;
RA Condon B.J., Leng Y., Wu D., Bushley K.E., Ohm R.A., Otillar R., Martin J.,
RA Schackwitz W., Grimwood J., MohdZainudin N., Xue C., Wang R., Manning V.A.,
RA Dhillon B., Tu Z.J., Steffenson B.J., Salamov A., Sun H., Lowry S.,
RA LaButti K., Han J., Copeland A., Lindquist E., Barry K., Schmutz J.,
RA Baker S.E., Ciuffetti L.M., Grigoriev I.V., Zhong S., Turgeon B.G.;
RT "Comparative genome structure, secondary metabolite, and effector coding
RT capacity across Cochliobolus pathogens.";
RL PLoS Genet. 9:E1003233-E1003233(2013).
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DR EMBL; KI964010; EUC44139.1; -; Genomic_DNA.
DR RefSeq; XP_007689310.1; XM_007691120.1.
DR AlphaFoldDB; W6Z9A3; -.
DR STRING; 930090.W6Z9A3; -.
DR GeneID; 19123360; -.
DR KEGG; bor:COCMIDRAFT_37950; -.
DR eggNOG; KOG1212; Eukaryota.
DR HOGENOM; CLU_009600_9_2_1; -.
DR OrthoDB; 731186at2759; -.
DR Proteomes; UP000054032; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.90.1300.10; Amidase signature (AS) domain; 1.
DR InterPro; IPR023631; Amidase_dom.
DR InterPro; IPR036928; AS_sf.
DR PANTHER; PTHR46072; AMIDASE-RELATED-RELATED; 1.
DR PANTHER; PTHR46072:SF5; GENERAL AMIDASE-C; 1.
DR Pfam; PF01425; Amidase; 1.
DR PIRSF; PIRSF001221; Amidase_fungi; 1.
DR SUPFAM; SSF75304; Amidase signature (AS) enzymes; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT DOMAIN 86..541
FT /note="Amidase"
FT /evidence="ECO:0000259|Pfam:PF01425"
FT ACT_SITE 142
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR001221-1"
FT ACT_SITE 218
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR001221-1"
FT ACT_SITE 242
FT /note="Acyl-ester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR001221-1"
FT BINDING 192
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR001221-2"
FT BINDING 218
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR001221-2"
FT BINDING 239..242
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR001221-2"
SQ SEQUENCE 552 AA; 60104 MW; 59B037EA5EFD0E7B CRC64;
MSSTPPIIDW QALAKSKRES VFAKIPKDWL LPTSQTSQYT ETSSISVLDV PRTCGILTDK
ELDITENYDA TDLIKMMANG HLKSTEVVTA FCKRAAVAQQ CVSCLTEIMF DEAMARAREC
DEYLEKEGKV LGPLHGLPIS LKDSFNVRGV QATLGYVSFI PHPPAATDSA LVTVLHSLGA
VFYCKTNLPQ TMMTADSQNN IFGRTLNPNK LSRTAGGSTG GEGALIAMKG SIMGVATDVA
GSNRIPAICC GGASLKPTAG RVPFAGGAAV GRLGSPGSVP VVIGPCGRTT RDFALFLQSV
SSTQPWLLDP NSLNVPWRSV QPSTQPLRFG LIRGCKERPL HPPIARALHS TAMKLKAEGH
EIVLLDDKIP DLYQTSILAW KFFMLDPRKT PFQYIKASGE PLIPSIATTG FPELKDWQAS
LDELWDMNVE KGRVLNQFHK LMVGEPAEGG TTQKGLDAIL MPGYQSVAPK HDTYGLPIYT
VVVNLLNYPS GILNVGKADK EKDKEFVKED VIYEPLYEPE ECEGLPTHVQ IVGKSMMDEE
LVEIMKVVEK LL
//
