ID W7HPH8_9PEZI Unreviewed; 1114 AA.
AC W7HPH8;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=Rho-type GTPase-activating protein 1 {ECO:0008006|Google:ProtNLM};
GN ORFNames=DRE_04804 {ECO:0000313|EMBL:EWC46011.1};
OS Drechslerella stenobrocha 248.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Orbiliomycetes;
OC Orbiliales; Orbiliaceae; Drechslerella.
OX NCBI_TaxID=1043628 {ECO:0000313|EMBL:EWC46011.1, ECO:0000313|Proteomes:UP000024837};
RN [1] {ECO:0000313|EMBL:EWC46011.1, ECO:0000313|Proteomes:UP000024837}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=248 {ECO:0000313|EMBL:EWC46011.1,
RC ECO:0000313|Proteomes:UP000024837};
RA Liu X., Zhang W., Liu K.;
RT "Drechslerella stenobrocha genome reveals carnivorous origination and
RT mechanical trapping mechanism of predatory fungi.";
RL Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KI966422; EWC46011.1; -; Genomic_DNA.
DR AlphaFoldDB; W7HPH8; -.
DR HOGENOM; CLU_001321_1_0_1; -.
DR Proteomes; UP000024837; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProt.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd09391; LIM1_Lrg1p_like; 1.
DR CDD; cd09392; LIM2_Lrg1p_like; 1.
DR CDD; cd04397; RhoGAP_fLRG1; 1.
DR Gene3D; 2.10.110.10; Cysteine Rich Protein; 4.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR InterPro; IPR001781; Znf_LIM.
DR PANTHER; PTHR14963; RHO GTPASE ACTIVATING PROTEIN 18,19-RELATED; 1.
DR PANTHER; PTHR14963:SF1; RHO GTPASE-ACTIVATING PROTEIN CONUNDRUM; 1.
DR Pfam; PF00412; LIM; 3.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00132; LIM; 3.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 3.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS00478; LIM_DOMAIN_1; 3.
DR PROSITE; PS50023; LIM_DOMAIN_2; 3.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW LIM domain {ECO:0000256|PROSITE-ProRule:PRU00125};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00125};
KW Reference proteome {ECO:0000313|Proteomes:UP000024837};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00125}.
FT DOMAIN 59..120
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT DOMAIN 123..183
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT DOMAIN 410..473
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT DOMAIN 753..955
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 1..58
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 658..677
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 990..1114
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 992..1006
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1031..1048
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1081..1095
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1097..1114
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1114 AA; 125307 MW; 47667F50750A5A14 CRC64;
MASPYASEPQ IRGQPLPPSL VPGASNDTSP QRRPDDRLAP FPPTDSKQKS PPKPESARRI
CKKCDQPLTG QFVRALGGTF HLDCFRCRDC GTIVAQKFFP VDADDGSGQY PLCETDYFKR
LDLLCHDCGG ALRGSYITAL ERKYHIEHFT CCVCPTIFGP QDSYYEHDGE VYCHYHYSTK
FAARCQGCQT AILKQFVEIF RNGFNQHWHP ECYMIHKFWN VKLAPSSEVP ELPRIVEEED
QDPSDSRRSV VREAEERMEE KVYRIWSVLS TYEESSAANI SDMLLHVSNG AYVDGVFVAE
KFIWHVELLF NSADNLDIEL CKASGEGLVY SREAKLLCKK IVAFFTLLSK TQETGAGKLG
VTQELLSLER DYNNIDAFNR FLVELSDLDA AKDAKPTFEV NSTLADLNSD LCQNCRNTIE
DECMQFGMPK WHISCFGCVS CSTSLKNDVD SAYYSALTSQ LLCANCASHV QDAQRGFEHV
SRLRQYVYLL RVALARLLSM LKEGGALSYT PVDDPNFVGY DDTNPTGFGP GALNAENRSK
THHGEGEGYN STVSDVRRLR STRLDQKLAS SGRKARQSRI IENENFNAEG SDQRERFRIV
EDRDINGETI NELTFGEAGT LTLDDIPRIA AQEQAREQRP NAFKHRTSGF FAPVGMHQPK
LMNGHQRDSK GEQVPPPRMR RYFSELSAID YFIIRHLACL AMLPLVSEHF SQEELLELIE
RGSKQTLWTK FTKGFKQDGG KNKKQKKTGG FGVPLEQLVE RDHAESSLGI GPGPLRVPAF
LDDAIAAMKQ LDMSVEGVFR KNGNIRRLKE LTALINAGNE NIDLVKEGPV QVAALLKKFL
RELPDPLLTF KLYKLFIASQ RMPDEEKKRR VLHLTCCLLP KHHRDSIEIL FSFLNWVASF
SHVDEESGSK MDVHNLATVI TPNILYTKGQ SPGMDDSFLA IEAIHNLIEC NERMCEVPED
LMMILSDPNM MATPDMTTKE ILKRYGEVAK FSSNTGRGQG NRSPPSRNKD GRPPPPIYHK
VADEPVTGGG ESWSGNGTVR QVQTPPAPDQ LQKGEFGYEN NDAPRLPEPM YAQENGNRSR
HSHSFSFDRE TSPGGRRMDY PSSNHQNPNL SAHT
//
