ID W7IMN4_9PSEU Unreviewed; 690 AA.
AC W7IMN4;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Putative peptidase {ECO:0000313|EMBL:EWC61623.1};
GN ORFNames=UO65_2981 {ECO:0000313|EMBL:EWC61623.1};
OS Actinokineospora spheciospongiae.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Actinokineospora.
OX NCBI_TaxID=909613 {ECO:0000313|EMBL:EWC61623.1, ECO:0000313|Proteomes:UP000019277};
RN [1] {ECO:0000313|EMBL:EWC61623.1, ECO:0000313|Proteomes:UP000019277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EG49 {ECO:0000313|EMBL:EWC61623.1,
RC ECO:0000313|Proteomes:UP000019277};
RX PubMed=24604655;
RA Harjes J., Ryu T., Abdelmohsen U.R., Moitinho-Silva L., Horn H., Ravasi T.,
RA Hentschel U.;
RT "Draft Genome Sequence of the Antitrypanosomally Active Sponge-Associated
RT Bacterium Actinokineospora sp. Strain EG49.";
RL Genome Announc. 2:e00160-14(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EWC61623.1}.
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DR EMBL; AYXG01000103; EWC61623.1; -; Genomic_DNA.
DR RefSeq; WP_035282889.1; NZ_AYXG01000103.1.
DR AlphaFoldDB; W7IMN4; -.
DR STRING; 909613.UO65_2981; -.
DR PATRIC; fig|909613.9.peg.2982; -.
DR eggNOG; COG1506; Bacteria.
DR OrthoDB; 9812921at2; -.
DR Proteomes; UP000019277; Unassembled WGS sequence.
DR GO; GO:0008236; F:serine-type peptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 2.140.10.30; Dipeptidylpeptidase IV, N-terminal domain; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR001375; Peptidase_S9.
DR InterPro; IPR002469; Peptidase_S9B_N.
DR PANTHER; PTHR11731:SF193; DIPEPTIDYL PEPTIDASE 9; 1.
DR PANTHER; PTHR11731; PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED; 1.
DR Pfam; PF00930; DPPIV_N; 1.
DR Pfam; PF00326; Peptidase_S9; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF82171; DPP6 N-terminal domain-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000019277}.
FT DOMAIN 111..379
FT /note="Dipeptidylpeptidase IV N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00930"
FT DOMAIN 490..689
FT /note="Peptidase S9 prolyl oligopeptidase catalytic"
FT /evidence="ECO:0000259|Pfam:PF00326"
FT REGION 60..95
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 74..90
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 690 AA; 73812 MW; EDEB5970C0764AAC CRC64;
MTSDTSFLRL QARTQRFTLG SPREFRIAAD GSHVLFLRSS SGEDRTHALW VQDLSTGQET
RLGDPGELLL GGTEELSAEE RARRERSREQ GGGVMGNATD AAARVCAFAL SGRLFVADAL
TGAAGEVATA TPIIDPRPDP GGTHVAYVSG GALRVVGVDG ADDRALAEPG GPDETYGLAE
FIAAEEMGRS RGFWWSPDGT RLLVAHADKS AVRRWHIADP ADPAATPHVV SYPAAGTDNV
TVRLEVIGLD GTRVPVDWDN RATPYLVAVH WSAAGKPLIA VQSRDQKTVE VRAVDPDTGA
TELLHTETDD TWVEISPGVP AWTPGGDLVR IAARDGANRL FVGEECVSGD LQVRSVLHVG
DDVLFTASAE DPTQVHVYTS GPNRVSTEDG VHSATRAGDV IVLVSWSLEW AGPKVRVLRG
GEEIGTVTSL ATEPPIVPDV RLLTVGERGL RVGLLYPTGH VPGTKVPVLM DPYGGPHAQR
VLSTRNAFVN PQWLADQGFA VLVADGHGTP GRGPEWERAI AGDFAGVTLA DQVDALHAVA
AEHPDLDLDR VGIRGWSYGG YLSALAVLRA PEVFHAAISG APVTDWRLYD THYTERYLGH
PDERPEVYDR NSLIDDAPNL DRPLLLIHGL ADDNVVVAHS LRLSTALVAA GRPHALLPLP
GVTHMAPQED DVAENFMLMQ LRWLKGALGV
//
