ID W7IN34_9PSEU Unreviewed; 926 AA.
AC W7IN34;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 24-JAN-2024, entry version 43.
DE SubName: Full=Transcriptional regulator, SARP family {ECO:0000313|EMBL:EWC61808.1};
GN ORFNames=UO65_2867 {ECO:0000313|EMBL:EWC61808.1};
OS Actinokineospora spheciospongiae.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Actinokineospora.
OX NCBI_TaxID=909613 {ECO:0000313|EMBL:EWC61808.1, ECO:0000313|Proteomes:UP000019277};
RN [1] {ECO:0000313|EMBL:EWC61808.1, ECO:0000313|Proteomes:UP000019277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EG49 {ECO:0000313|EMBL:EWC61808.1,
RC ECO:0000313|Proteomes:UP000019277};
RX PubMed=24604655;
RA Harjes J., Ryu T., Abdelmohsen U.R., Moitinho-Silva L., Horn H., Ravasi T.,
RA Hentschel U.;
RT "Draft Genome Sequence of the Antitrypanosomally Active Sponge-Associated
RT Bacterium Actinokineospora sp. Strain EG49.";
RL Genome Announc. 2:e00160-14(2014).
CC -!- SIMILARITY: Belongs to the AfsR/DnrI/RedD regulatory family.
CC {ECO:0000256|ARBA:ARBA00005820}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EWC61808.1}.
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DR EMBL; AYXG01000101; EWC61808.1; -; Genomic_DNA.
DR RefSeq; WP_035282654.1; NZ_AYXG01000101.1.
DR AlphaFoldDB; W7IN34; -.
DR STRING; 909613.UO65_2867; -.
DR PATRIC; fig|909613.9.peg.2867; -.
DR eggNOG; COG3629; Bacteria.
DR eggNOG; COG3903; Bacteria.
DR OrthoDB; 3275754at2; -.
DR Proteomes; UP000019277; Unassembled WGS sequence.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd15831; BTAD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005158; BTAD.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR47691:SF3; HTH-TYPE TRANSCRIPTIONAL REGULATOR RV0890C-RELATED; 1.
DR PANTHER; PTHR47691; REGULATOR-RELATED; 1.
DR Pfam; PF03704; BTAD; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF13424; TPR_12; 1.
DR Pfam; PF00486; Trans_reg_C; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM01043; BTAD; 1.
DR SMART; SM00028; TPR; 5.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS51755; OMPR_PHOB; 1.
DR PROSITE; PS50005; TPR; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU01091};
KW Reference proteome {ECO:0000313|Proteomes:UP000019277};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT DOMAIN 1..91
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000259|PROSITE:PS51755"
FT REPEAT 706..739
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT DNA_BIND 1..91
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01091"
SQ SEQUENCE 926 AA; 98786 MW; E876A0C4CB8A1BCF CRC64;
MLRLLGEVAV HAGGHRVDLG PARQRCLLAA LALDAGRVVP VDQLVERVWA EDVPRRGRAT
LHSYLSRLRQ ALAGVDWLEI ARRPGGYALV TTGARAVDVV AFRDLCARAR SEPDPAEAAR
LLTDALDLWR GEALTGLDSA WAAVERAGLD EERIAAQCDL VDARLRTGHG EHLVAELATR
VANRPLDERV AGQYMLALHQ AGRTADALAH YRRIRDRLVE ELGTEPGTRL QQWHGTLLAA
GRAPTITPAA LCRQLPRAPR RFVGRHRDLA RLDAALAGVD PGAPVVISAL TGAGGIGKTW
LALHWAHRHA DRFPDGQLFV DLRGFSPEGA PLPAAAAVRG FLDAFGVEPA RIPVDPHAAA
TLFRGLVAGK RVLVVLDNAA DSAQVAPLLP DSDRCTVLIT SRTVLTGLLT RHGAGHLPLD
VLSAGEARAL LADRIGTDRA TAEAEGLDRL VELCGGFPLA LSLVAAHALT RPRLTLVGLA
AALGDLGLEA LADTDPAANL RAVLSLSLTV LTPEQATAYA LLGTAPGRDI GLPAAASLLG
LPETAAAAVL RALEQASLLT GSDTGRHRMH DLIRLHAGET AQDLPADVVT AALDRLTDFY
LHTARNADAV FNPDRPSLDL APPVAGCAPL TAEDDAAATR WFSAERDNLL ATQRAAADRQ
LHRVTWGLAG ALETYLRRRG HLRDRLAVWT AAVDAVAHLS DPTAHVRAHR LLGRAHADLG
QHDEAGRCLR AALALAEHHD DDLNQAHTHR TLASAAMSRG DSHQARDHAE HALRICRTLG
DPLWEAGALN AVGWYAAISG DLAAGREHCR EAYDLFLRHD NTEGQATTLD SLGYIAHHSG
RHADSVDHYL TALALLREIG SAAEEADTLD RLGHAHAALG QHDRARAAWQ SALGRYEEQG
REGNARELRA LLHSARVDTP AEGAGG
//
