ID   W7IQU7_9PSEU            Unreviewed;       375 AA.
AC   W7IQU7;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Putative transcriptional regulator, ROK family {ECO:0000313|EMBL:EWC63265.1};
GN   ORFNames=UO65_1479 {ECO:0000313|EMBL:EWC63265.1};
OS   Actinokineospora spheciospongiae.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Actinokineospora.
OX   NCBI_TaxID=909613 {ECO:0000313|EMBL:EWC63265.1, ECO:0000313|Proteomes:UP000019277};
RN   [1] {ECO:0000313|EMBL:EWC63265.1, ECO:0000313|Proteomes:UP000019277}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=EG49 {ECO:0000313|EMBL:EWC63265.1,
RC   ECO:0000313|Proteomes:UP000019277};
RX   PubMed=24604655;
RA   Harjes J., Ryu T., Abdelmohsen U.R., Moitinho-Silva L., Horn H., Ravasi T.,
RA   Hentschel U.;
RT   "Draft Genome Sequence of the Antitrypanosomally Active Sponge-Associated
RT   Bacterium Actinokineospora sp. Strain EG49.";
RL   Genome Announc. 2:e00160-14(2014).
CC   -!- SIMILARITY: Belongs to the ROK (NagC/XylR) family.
CC       {ECO:0000256|ARBA:ARBA00006479}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EWC63265.1}.
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DR   EMBL; AYXG01000051; EWC63265.1; -; Genomic_DNA.
DR   AlphaFoldDB; W7IQU7; -.
DR   STRING; 909613.UO65_1479; -.
DR   eggNOG; COG1846; Bacteria.
DR   eggNOG; COG1940; Bacteria.
DR   Proteomes; UP000019277; Unassembled WGS sequence.
DR   CDD; cd00012; NBD_sugar-kinase_HSP70_actin; 1.
DR   Gene3D; 3.30.420.40; -; 2.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR000600; ROK.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR18964:SF177; N-ACETYLMANNOSAMINE KINASE; 1.
DR   PANTHER; PTHR18964; ROK (REPRESSOR, ORF, KINASE) FAMILY; 1.
DR   Pfam; PF00480; ROK; 1.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000019277}.
SQ   SEQUENCE   375 AA;  38913 MW;  F6C25F8869250491 CRC64;
     MIRRAGPLSR AAIGERTGLS LPTVSRSVSA LIGVGLVREH PELVPVGSIG RPRVPLHLDD
     GVFAVGGVHI GVSTTTYGLA DLRGAIIASQ ELPTPSGDAE DALAHIAGKL RAFLRRFPRR
     VVLGVGLASG GQVDTERGLL DHERLGWRSV PAAEALRRAT GLPVLLEGHV AAMASAELVF
     GRGASAPSLL YFYAREVVGI ALVVEGRLHR GPWGGSTIAH LPVGGSAECP CGALGCLEAE
     VCDRTVAERA AAAGVVDEAD IRLVRAAAAG GDSRAVGLLT DRAHTIGRAA AILRDVLNPH
     AVVLGGQAVT EDPDRLPDLL RSFRDTTTLP GPADLVSVTP FGPAVQAVAA CTGLLTRVFE
     NPFDFVRPTR KAPTP
//