ID W7IVN9_9PSEU Unreviewed; 349 AA.
AC W7IVN9;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=Nicotinamide-nucleotide adenylyltransferase, NadR family {ECO:0000313|EMBL:EWC58069.1};
DE EC=2.7.1.22 {ECO:0000313|EMBL:EWC58069.1};
DE EC=2.7.7.1 {ECO:0000313|EMBL:EWC58069.1};
GN ORFNames=UO65_6680 {ECO:0000313|EMBL:EWC58069.1};
OS Actinokineospora spheciospongiae.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Actinokineospora.
OX NCBI_TaxID=909613 {ECO:0000313|EMBL:EWC58069.1, ECO:0000313|Proteomes:UP000019277};
RN [1] {ECO:0000313|EMBL:EWC58069.1, ECO:0000313|Proteomes:UP000019277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EG49 {ECO:0000313|EMBL:EWC58069.1,
RC ECO:0000313|Proteomes:UP000019277};
RX PubMed=24604655;
RA Harjes J., Ryu T., Abdelmohsen U.R., Moitinho-Silva L., Horn H., Ravasi T.,
RA Hentschel U.;
RT "Draft Genome Sequence of the Antitrypanosomally Active Sponge-Associated
RT Bacterium Actinokineospora sp. Strain EG49.";
RL Genome Announc. 2:e00160-14(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EWC58069.1}.
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DR EMBL; AYXG01000263; EWC58069.1; -; Genomic_DNA.
DR RefSeq; WP_035290856.1; NZ_AYXG01000263.1.
DR AlphaFoldDB; W7IVN9; -.
DR STRING; 909613.UO65_6680; -.
DR PATRIC; fig|909613.9.peg.6674; -.
DR eggNOG; COG3172; Bacteria.
DR Proteomes; UP000019277; Unassembled WGS sequence.
DR GO; GO:0000309; F:nicotinamide-nucleotide adenylyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0050262; F:ribosylnicotinamide kinase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR038727; NadR/Ttd14_AAA_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR PANTHER; PTHR37512:SF1; AAA_28 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR37512; TRIFUNCTIONAL NAD BIOSYNTHESIS/REGULATOR PROTEIN NADR; 1.
DR Pfam; PF13521; AAA_28; 1.
DR SUPFAM; SSF52374; Nucleotidylyl transferase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Nucleotidyltransferase {ECO:0000313|EMBL:EWC58069.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000019277};
KW Transferase {ECO:0000313|EMBL:EWC58069.1}.
FT DOMAIN 169..327
FT /note="NadR/Ttd14 AAA"
FT /evidence="ECO:0000259|Pfam:PF13521"
SQ SEQUENCE 349 AA; 37496 MW; 03410062B1315AB9 CRC64;
MRFRHALVLG KFYPPHAGHH HLIRTAAAAS ERTTVAVLGS SAESLSIADR VRWLAEEHAA
DPGVRVLGDL DDHPVDYSDD AVWDLHVGVT RSVLARRAIA EGDPSGAAVD AVFSSEDYGV
ELARRLDATH VPVDPARLAF PVSGTAVRAD VRGQWANLAR PTRAGLATRV VVLGAESTGT
TTLATALAAH YGGTAVPEYG REHTAAKLAA KAPVWTVGDF VDVAVRQGAD EDAAAPAAPV
LVCDNDPWAA TVWCERYLGF GHPEVDAAVG DRRPALYLLT DHVAVEFEQD GTRDGEHLRP
WMTARFVRGL RGRGVPWLLL TGSREHRLRR AVRACEAAAA ARFTFTDPL
//
