ID W7IZC4_9PSEU Unreviewed; 200 AA.
AC W7IZC4;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Transcriptional regulator, TetR family {ECO:0000313|EMBL:EWC59409.1};
GN ORFNames=UO65_5355 {ECO:0000313|EMBL:EWC59409.1};
OS Actinokineospora spheciospongiae.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Actinokineospora.
OX NCBI_TaxID=909613 {ECO:0000313|EMBL:EWC59409.1, ECO:0000313|Proteomes:UP000019277};
RN [1] {ECO:0000313|EMBL:EWC59409.1, ECO:0000313|Proteomes:UP000019277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EG49 {ECO:0000313|EMBL:EWC59409.1,
RC ECO:0000313|Proteomes:UP000019277};
RX PubMed=24604655;
RA Harjes J., Ryu T., Abdelmohsen U.R., Moitinho-Silva L., Horn H., Ravasi T.,
RA Hentschel U.;
RT "Draft Genome Sequence of the Antitrypanosomally Active Sponge-Associated
RT Bacterium Actinokineospora sp. Strain EG49.";
RL Genome Announc. 2:e00160-14(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EWC59409.1}.
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DR EMBL; AYXG01000206; EWC59409.1; -; Genomic_DNA.
DR RefSeq; WP_052021798.1; NZ_AYXG01000206.1.
DR AlphaFoldDB; W7IZC4; -.
DR STRING; 909613.UO65_5355; -.
DR PATRIC; fig|909613.9.peg.5349; -.
DR eggNOG; COG1309; Bacteria.
DR OrthoDB; 9806334at2; -.
DR Proteomes; UP000019277; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:UniProt.
DR Gene3D; 1.10.357.10; Tetracycline Repressor, domain 2; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001647; HTH_TetR.
DR InterPro; IPR041479; TetR_CgmR_C.
DR PANTHER; PTHR30055; HTH-TYPE TRANSCRIPTIONAL REGULATOR RUTR; 1.
DR PANTHER; PTHR30055:SF226; HTH-TYPE TRANSCRIPTIONAL REPRESSOR RV1474C; 1.
DR Pfam; PF17937; TetR_C_28; 1.
DR Pfam; PF00440; TetR_N; 1.
DR PRINTS; PR00455; HTHTETR.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS50977; HTH_TETR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00335};
KW Reference proteome {ECO:0000313|Proteomes:UP000019277};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 10..69
FT /note="HTH tetR-type"
FT /evidence="ECO:0000259|PROSITE:PS50977"
FT DNA_BIND 32..51
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
SQ SEQUENCE 200 AA; 21187 MW; 23F3F8936C88064F CRC64;
MPRKAGRSAE DTRRALLDAA GAAVRARGVS ASLDDIARQA GVSKGGLLHH FASKDELVRA
LAEDLLAGFR ADVTAAVDPA DTAPGALTRA YVRVCADFAR DDVAVHELQP LIGHLSTIPE
VAEIARADAR RWRDDLRADG LPDHITALVV AAADGISAAP DWSTPLDDSA LRGLETLLLA
LTTDTRLWDH LDVAPGQLPR
//
