ID W7J6H0_9PSEU Unreviewed; 367 AA.
AC W7J6H0;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Octaprenyl diphosphate synthase {ECO:0000313|EMBL:EWC64572.1};
DE EC=2.5.1.1 {ECO:0000313|EMBL:EWC64572.1};
DE EC=2.5.1.10 {ECO:0000313|EMBL:EWC64572.1};
DE EC=2.5.1.29 {ECO:0000313|EMBL:EWC64572.1};
DE EC=2.5.1.90 {ECO:0000313|EMBL:EWC64572.1};
GN ORFNames=UO65_0179 {ECO:0000313|EMBL:EWC64572.1};
OS Actinokineospora spheciospongiae.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Actinokineospora.
OX NCBI_TaxID=909613 {ECO:0000313|EMBL:EWC64572.1, ECO:0000313|Proteomes:UP000019277};
RN [1] {ECO:0000313|EMBL:EWC64572.1, ECO:0000313|Proteomes:UP000019277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EG49 {ECO:0000313|EMBL:EWC64572.1,
RC ECO:0000313|Proteomes:UP000019277};
RX PubMed=24604655;
RA Harjes J., Ryu T., Abdelmohsen U.R., Moitinho-Silva L., Horn H., Ravasi T.,
RA Hentschel U.;
RT "Draft Genome Sequence of the Antitrypanosomally Active Sponge-Associated
RT Bacterium Actinokineospora sp. Strain EG49.";
RL Genome Announc. 2:e00160-14(2014).
CC -!- SIMILARITY: Belongs to the FPP/GGPP synthase family.
CC {ECO:0000256|ARBA:ARBA00006706, ECO:0000256|RuleBase:RU004466}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EWC64572.1}.
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DR EMBL; AYXG01000004; EWC64572.1; -; Genomic_DNA.
DR AlphaFoldDB; W7J6H0; -.
DR STRING; 909613.UO65_0179; -.
DR PATRIC; fig|909613.9.peg.187; -.
DR eggNOG; COG0142; Bacteria.
DR Proteomes; UP000019277; Unassembled WGS sequence.
DR GO; GO:0004161; F:dimethylallyltranstransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0004311; F:farnesyltranstransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0004337; F:geranyltranstransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0106350; F:octaprenyl pyrophosphate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR CDD; cd00685; Trans_IPPS_HT; 1.
DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR InterPro; IPR000092; Polyprenyl_synt.
DR InterPro; IPR033749; Polyprenyl_synt_CS.
DR PANTHER; PTHR12001:SF88; (2E,6E)-FARNESYL DIPHOSPHATE SYNTHASE; 1.
DR PANTHER; PTHR12001; GERANYLGERANYL PYROPHOSPHATE SYNTHASE; 1.
DR Pfam; PF00348; polyprenyl_synt; 1.
DR SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR SUPFAM; SSF48576; Terpenoid synthases; 1.
DR PROSITE; PS00723; POLYPRENYL_SYNTHASE_1; 1.
DR PROSITE; PS00444; POLYPRENYL_SYNTHASE_2; 1.
PE 3: Inferred from homology;
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Reference proteome {ECO:0000313|Proteomes:UP000019277};
KW Transferase {ECO:0000256|RuleBase:RU004466, ECO:0000313|EMBL:EWC64572.1}.
SQ SEQUENCE 367 AA; 38767 MW; 5C6E19A1D64DEBB1 CRC64;
MSLATQMEPH SPVSGKALAA AVRRQVDVVL DGFLAGKAAN AADECLPPVV DTVRRFVAGG
KRLRPVFCHC GWLAAGGDPD ERAVAAVGAA LELFHSFALI HDDLMDGSDL RRGNPTVHRE
PAARCPDRAG GTAAVAADRF GENAAILLGD LCLVWSDELL HGTGFDADRV AAARPFLDAM
RTEVMAGQYL DLHHRPAGDA LAHAWRVVRL KTARYTVERP LQIGVALAGG DAELARRCAE
YGRPLGEAFQ LRDDLLGVFG DPAVTGKPVL DDLREGKPTV LVAVAGQRAT AAQRAVLREL
YGNPLLDEAG AAALRAVIDG TGAAALVERL IADRTEQALS ALADSAIPHP VRGVLADLAD
TVVHRDR
//
