ID   W7JPE6_PLAFA            Unreviewed;      1201 AA.
AC   W7JPE6;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   22-FEB-2023, entry version 31.
DE   RecName: Full=TFIIS N-terminal domain-containing protein {ECO:0000259|PROSITE:PS51319};
GN   ORFNames=C923_02425 {ECO:0000313|EMBL:EWC76918.1};
OS   Plasmodium falciparum UGT5.1.
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX   NCBI_TaxID=1237627 {ECO:0000313|EMBL:EWC76918.1, ECO:0000313|Proteomes:UP000030697};
RN   [1] {ECO:0000313|EMBL:EWC76918.1, ECO:0000313|Proteomes:UP000030697}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UGT5.1 {ECO:0000313|EMBL:EWC76918.1,
RC   ECO:0000313|Proteomes:UP000030697};
RG   The Broad Institute Genome Sequencing Platform;
RG   The Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Neafsey D., Cheeseman I., Volkman S., Adams J., Walker B., Young S.K.,
RA   Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA   Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA   Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA   Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Plasmodium falciparum UGT5.1.";
RL   Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00649}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; KE124545; EWC76918.1; -; Genomic_DNA.
DR   AlphaFoldDB; W7JPE6; -.
DR   EnsemblProtists; EWC76918; EWC76918; C923_02425.
DR   Proteomes; UP000030697; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   Gene3D; 1.20.930.10; Conserved domain common to transcription factors TFIIS, elongin A, CRSP70; 1.
DR   InterPro; IPR035441; TFIIS/LEDGF_dom_sf.
DR   InterPro; IPR017923; TFIIS_N.
DR   Pfam; PF08711; Med26; 1.
DR   SUPFAM; SSF47676; Conserved domain common to transcription factors TFIIS, elongin A, CRSP70; 1.
DR   PROSITE; PS51319; TFIIS_N; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Nucleus {ECO:0000256|PROSITE-ProRule:PRU00649};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030697}.
FT   DOMAIN          353..438
FT                   /note="TFIIS N-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51319"
FT   REGION          54..84
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          691..815
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          926..964
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          463..490
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        64..80
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        691..794
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        795..815
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1201 AA;  140429 MW;  061D3DC4E9C06CD5 CRC64;
     MENISIENIN VNEIHNKKRK QNVVQKKNTS NHEMINTSTD IVICGENHKP KELIKRTKKK
     SKISNAGNME ISQENDEGKN SLSLEGYLKN GDNIDDVYNY NSSNNNEEDE KNVDIINNDY
     KTKDDTNNIL ILNNNNNNNN NNKLNSILPQ DNSDDNKSIN ICEDGNINNE NIKKKNNKEI
     ISELKNTLNI VENSNAQHNI EGLNKEEITM LDSWYFANKM KIIPYLFDDK PIHINLLNSL
     YMLHPYFKNH KTKIIIYLRF VKNKYQNIIK KNSEKYNNQT IEIECKATML KILGNKIENF
     KDIQYMDKVI TLIQNENSYI NIKYFFLFIL DVSNDYIIYE NFLQQNGLLC IKNILHNIAE
     KKIIKKNIPL LIILLNFLKN LNINLNHLKT TLIGIPINFI ARNKIDEQNN LDYVTDNSKV
     IQLAKELINK WKLIRDQALN NNNNNNNNEN QNDQNGQIEI VNINKVEKDI EEAQKENANN
     NNNNNNFMSN MINATTNHHI NIINDTKPKS NKKSANSVSK NENKNIMLEI IDNINEEYEK
     KKKRHLEYKK AKIEGKIKKF SALKNSTEIK KKTENLLINL SKDNLIRPHS DNNNNNNNNN
     RIHSNPMINN NILSHNMNGM DYNGIYSNDR KNYNNNNNII NNEHLSRDIY NDGMASSYNH
     MNKNVHSQNY TRMGDHSMDS PNYMNKYNMN NRHNSNEAST NRQPFPQYGP INTPPSINKK
     NAHSNNNNNN NNKYINDNYY NNNSMIPNKY SPDGRYSPSN LHTKQFQNEK YGNVSPHIND
     PLINKNNYER HNYNPSNRHT YDRKSNEKNY KPSKFSTKRT NKFTYDESPF DNNINVKDAK
     QNIKDPFEYY SNNNMQKEPY KNNKKLEIEN IRNLLNIDAN VSSQQYDNND INEQMNIQTM
     KNDNNFKNSK QKRIMEQFES LNLLLNGSNI NNNNNNNNNN NNNNNNNNNN NNNNNNNNNM
     DEPLDSSLDD IFSFFKKFEN VQENYQINKS DFIYPASIFQ DSEIKKNDII ITFKYDSHDN
     IPIYIKYNTP SNKNMINTKF SNNNYPNQLN NTEPYNNMDR DHIIKNSNQN FNILPLSELF
     HQSNINELKL PPIMPPILPN LNNSQNIIPP IMFPYNNSND YTNTNINSAF SSDNISYNNN
     SSINEFVKIF DEGIQKILLK NKDLANLLMN KPDVVQKMLK GPQYINEALS SLENELKNWN
     R
//