ID W7JTL0_PLAFO Unreviewed; 641 AA.
AC W7JTL0;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 24-JAN-2024, entry version 46.
DE RecName: Full=Fe-S cluster assembly protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PFNF54_03256 {ECO:0000313|EMBL:EWC88026.1};
OS Plasmodium falciparum (isolate NF54).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=5843 {ECO:0000313|EMBL:EWC88026.1, ECO:0000313|Proteomes:UP000030673};
RN [1] {ECO:0000313|EMBL:EWC88026.1, ECO:0000313|Proteomes:UP000030673}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NF54 {ECO:0000313|EMBL:EWC88026.1,
RC ECO:0000313|Proteomes:UP000030673};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Cheeseman I., Volkman S., Adams J., Walker B., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Plasmodium falciparum NF54.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the Mrp/NBP35 ATP-binding proteins family.
CC {ECO:0000256|ARBA:ARBA00024036}.
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DR EMBL; KE123835; EWC88026.1; -; Genomic_DNA.
DR AlphaFoldDB; W7JTL0; -.
DR EnsemblProtists; EWC88026; EWC88026; PFNF54_03256.
DR OMA; VKIVWSD; -.
DR Proteomes; UP000030673; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140663; F:ATP-dependent FeS chaperone activity; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016226; P:iron-sulfur cluster assembly; IEA:InterPro.
DR CDD; cd02037; Mrp_NBP35; 1.
DR Gene3D; 3.30.2020.30; -; 1.
DR Gene3D; 3.30.300.130; Fe-S cluster assembly (FSCA); 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR034904; FSCA_dom_sf.
DR InterPro; IPR010376; GBBH-like_N.
DR InterPro; IPR038492; GBBH-like_N_sf.
DR InterPro; IPR002744; MIP18-like.
DR InterPro; IPR019591; Mrp/NBP35_ATP-bd.
DR InterPro; IPR044304; NUBPL-like.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR033756; YlxH/NBP35.
DR PANTHER; PTHR42961; IRON-SULFUR PROTEIN NUBPL; 1.
DR PANTHER; PTHR42961:SF2; IRON-SULFUR PROTEIN NUBPL; 1.
DR Pfam; PF01883; FeS_assembly_P; 1.
DR Pfam; PF06155; GBBH-like_N; 1.
DR Pfam; PF10609; ParA; 2.
DR SUPFAM; SSF117916; Fe-S cluster assembly (FSCA) domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000030673}.
FT DOMAIN 3..63
FT /note="MIP18 family-like"
FT /evidence="ECO:0000259|Pfam:PF01883"
FT DOMAIN 537..615
FT /note="Gamma-butyrobetaine hydroxylase-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF06155"
FT REGION 197..238
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 197..224
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 641 AA; 75562 MW; D0A4E12FC1DEBC5B CRC64;
MCIDPDLKKN IVELNFVRNL KINEDEKGEK YFVEFDLNLT TPACPVKDDL LRECKEKLGL
FEWIHDININ ITFINFNEKR GNNKNKIENI ILIYSCKGGV GKSFFSVNFS YYLKKKGASV
GILDADINGP SLPTLLPFDY EYVKFKVVNK KKDEPTKGKN GYIYNDDMNN NNNDDVDNND
MNNNIDNNNI DNNNIHNNNI HNNNLHNNNL HNNNLHNNLH NNLQNSDGKK KKKKPNRENL
LNIFNSKNYN KLSNDDKKNS GTIEYDENLS MIEPLIYNDV KLMSYAYIKN KMNLGFSSFR
GPILNELIKE FLYHVNWGIL DYLIIDMPPG TNDIHLNLFE SEKIDGIIMI TTPNDLSTND
VEKGINMCNF FNIPIVCLVI NMNYFICDNC DKKHYIFNNT DMKSLKDKIR NIYEIPFHPI
LAKNVYTHKH NYKKDTTNVL SIQDANIKHN EYTQQKMEHI SEEHIKHFPF ILAYDKNHFL
IEHLENLFQQ IVREIAILKY NHNLNIPNLQ IYKKNYLQLS FDTIQNKYVF SDDVLICHIK
DIRRKCKCLI CKENKKEKKC IQYDKNNNHN NYNFKKKISL FPPNIYVKDI IPLGIYNVKI
VWSDNHSSIY SYVYLKHLFE KKRINNNNLF CKTNNSGMYE W
//
