ID   W7K0I8_PLAFO            Unreviewed;      1004 AA.
AC   W7K0I8;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   03-MAY-2023, entry version 36.
DE   SubName: Full=Alpha/beta-hydrolase {ECO:0000313|EMBL:KAF4327793.1};
GN   ORFNames=CYL21_3994 {ECO:0000313|EMBL:KAF4327793.1}, PFNF54_04382
GN   {ECO:0000313|EMBL:EWC86829.1};
OS   Plasmodium falciparum (isolate NF54).
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX   NCBI_TaxID=5843 {ECO:0000313|EMBL:EWC86829.1, ECO:0000313|Proteomes:UP000030673};
RN   [1] {ECO:0000313|EMBL:EWC86829.1, ECO:0000313|Proteomes:UP000030673}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NF54 {ECO:0000313|EMBL:EWC86829.1,
RC   ECO:0000313|Proteomes:UP000030673};
RG   The Broad Institute Genome Sequencing Platform;
RG   The Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Neafsey D., Cheeseman I., Volkman S., Adams J., Walker B., Young S.K.,
RA   Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA   Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA   Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA   Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Plasmodium falciparum NF54.";
RL   Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:KAF4327793.1, ECO:0000313|Proteomes:UP000754359}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NF54 {ECO:0000313|EMBL:KAF4327793.1};
RA   Baumgarten S., Treeck M., Scherf A.;
RT   "Genome assembly of Plasmodium falciparum NF54 DiCre.";
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KE123862; EWC86829.1; -; Genomic_DNA.
DR   EMBL; QFXU01000018; KAF4327793.1; -; Genomic_DNA.
DR   AlphaFoldDB; W7K0I8; -.
DR   EnsemblProtists; EWC86829; EWC86829; PFNF54_04382.
DR   VEuPathDB; PlasmoDB:PfNF54_130033900; -.
DR   OMA; FDHGYYK; -.
DR   Proteomes; UP000030673; Unassembled WGS sequence.
DR   Proteomes; UP000754359; Unassembled WGS sequence.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR022742; Hydrolase_4.
DR   PANTHER; PTHR11614:SF87; MONOGLYCERIDE LIPASE; 1.
DR   PANTHER; PTHR11614; PHOSPHOLIPASE-RELATED; 1.
DR   Pfam; PF12146; Hydrolase_4; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000030673}.
FT   DOMAIN          468..686
FT                   /note="Serine aminopeptidase S33"
FT                   /evidence="ECO:0000259|Pfam:PF12146"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          141..188
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          343..366
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          378..435
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          693..763
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          790..813
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          828..874
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        144..188
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        732..746
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        747..763
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1004 AA;  115890 MW;  6B0902B57A770D7C CRC64;
     MASGKGKENI STKDTRNDED NTNKKYFVDV IKRLNKNDNK KYYLDEENKT EIQDAETKFK
     NELNEEIYNK DDYIIYDDGN PEIQFFTNKQ KLKIARYSWK AENPKAYVFA LHGITSHLRN
     EYLNYYGRPI WAHKKDEVHD NNISSDDNNN IPSDDNNNIP SGDNNNIPSG DNNSNNNNNN
     NANNDYKPRL DKYTNELKES EKNNNDYIIK DNLTNTINYG YHRGNVGEDI NNDIEKTHER
     GKSIEVKSEV NIPKYTSTSS LNKVNGNNNI ECENLRKNSL KSRESYFMNN EPEKSVLNEG
     DVYESTSSLS CSSSELMDKK TLEKKLTMFL SCSSCMSNYN ENTNGLNNDK KFETGSDNEM
     NSDDNMMVDD DNVLLIDENY NSSNSNNNSK NNGSSNNSKN NSKNNSKNNS KHSSKNNSKN
     NKNNNKNINN DSNNNNNYDG CNDNTVYYCS MCGSVCNYCN CGERTLSYKN SWIEKLNENN
     FSFFGIDNQS HGLSEGSRNQ RCFVEDFEHF ISDAIQALEI FINEWKEKNE MKPIILMGLS
     MGGCIALRTL ETINRLNKEW KSYVKCLILV SPMISLGKQK NKISNKLLIS ATKFLKYFFP
     LLKVNVKESN AKYAWIKHDS DIDPFQYCGP LNIKIAAECV SAADNCLKYH ILKYVEESDT
     DIMVIQSKHD CIVDPSGSID FMKKMVRLYN KKEEKRLKNN NKKYSQTSTY STKEHNEKLA
     TVHAVENNND DNNDNNNDDN NEDNNDDNND NNNNNNNNDN NDIVTRFQND LISKDKENTT
     INSFMNKPFI NSAKDNTINN NETDDHQNEQ TLNDGTLTNN NTMMMMTIND DNNNENSEII
     NKNNNNNNNN KNNNNNNNNN NNNYSSKGSI QRTNYQNPIH DEDKIKIQKL MQSYEKADYT
     QANLYNSEDY SNQTCNKFFE NSYIKLSKST LKNEKELWNP FDHGHYKNFI LKKNNKNCNF
     SKEEDKYKKL SIYILKYGCH TLPGEPDSKS SANILVNWLN NIFH
//