ID W7K3S1_PLAFO Unreviewed; 497 AA.
AC W7K3S1;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=XPA binding protein 1 {ECO:0000313|EMBL:KAF4327397.1};
GN ORFNames=CK202_1865 {ECO:0000313|EMBL:PKC48441.1}, CYL21_4895
GN {ECO:0000313|EMBL:KAF4327397.1}, PFNF54_03555
GN {ECO:0000313|EMBL:EWC87430.1};
OS Plasmodium falciparum (isolate NF54).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=5843 {ECO:0000313|EMBL:EWC87430.1, ECO:0000313|Proteomes:UP000030673};
RN [1] {ECO:0000313|EMBL:EWC87430.1, ECO:0000313|Proteomes:UP000030673}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NF54 {ECO:0000313|EMBL:EWC87430.1,
RC ECO:0000313|Proteomes:UP000030673};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Cheeseman I., Volkman S., Adams J., Walker B., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Plasmodium falciparum NF54.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:PKC48441.1, ECO:0000313|Proteomes:UP000232684}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NF54 {ECO:0000313|EMBL:PKC48441.1};
RA Bryant J.M., Baumgarten S., Scheidig-Benatar C., Scherf A.;
RT "Plasmodium falciparum NF54 genome assembly.";
RL Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:KAF4327397.1, ECO:0000313|Proteomes:UP000754359}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NF54 {ECO:0000313|EMBL:KAF4327397.1};
RA Baumgarten S., Treeck M., Scherf A.;
RT "Genome assembly of Plasmodium falciparum NF54 DiCre.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the GPN-loop GTPase family.
CC {ECO:0000256|ARBA:ARBA00005290}.
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DR EMBL; KE123842; EWC87430.1; -; Genomic_DNA.
DR EMBL; QFXU01000022; KAF4327397.1; -; Genomic_DNA.
DR EMBL; NYMT01000004; PKC48441.1; -; Genomic_DNA.
DR AlphaFoldDB; W7K3S1; -.
DR SMR; W7K3S1; -.
DR EnsemblProtists; EWC87430; EWC87430; PFNF54_03555.
DR VEuPathDB; PlasmoDB:PfNF54_120006700; -.
DR OMA; FPQFHVI; -.
DR Proteomes; UP000030673; Unassembled WGS sequence.
DR Proteomes; UP000232684; Unassembled WGS sequence.
DR Proteomes; UP000754359; Unassembled WGS sequence.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR CDD; cd17870; GPN1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR004130; Gpn.
DR InterPro; IPR030230; Gpn1/Npa3/XAB1.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR21231:SF8; GPN-LOOP GTPASE 1; 1.
DR PANTHER; PTHR21231; XPA-BINDING PROTEIN 1-RELATED; 1.
DR Pfam; PF03029; ATP_bind_1; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000030673}.
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 114..142
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 26..56
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 114..130
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 497 AA; 57644 MW; A139D1C8E058769E CRC64;
MEETINDKVN KIEKTNNSDR KKDEEIMNKI KNYKILNNNN NNNEEEEEEE KNIKEYPNNN
IINKENHNVL IKENYDVTNK NDDTTKINDD NSNVKINCES SNEKREVSDL NTYSDNDVNV
NINNSSNNIE KENPPKDKHY DNNINKISSY GDNKQNNILD DTDMSIHNNL NDTSNEKKNV
IISNEDIIQN NNSKTCGNLK NYYKDLPTVI IVIGMAGSGK TTYVGSLYNY LKVEQKKKVY
TMNLDPAVKY VQYPLNIDIR DSIKYHEIMK EYKLGPNGAI MTCLNLFATR FDKVIEILEK
RKSKLHYIIV DTPGQIEVFN WSASGNIILE TLSVSFPVVI NYIIDTVRCE RPITFMSNML
YACSVLYKSR LPFLACFNKT DIIKHDKCIE WMTNYDTFND DVLNDESYMA SFSRSCALMI
NEFYEGIKTV GVSSKTNEGF NNILKNLQIL KEEYLNEYVS SIEKQMKKIK QRKEKDVKIK
MEALLMEKQK EISSSKS
//
