ID   W7KW21_9CREN            Unreviewed;       495 AA.
AC   W7KW21;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE            EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN   ORFNames=ASUL_03244 {ECO:0000313|EMBL:EWG07491.1};
OS   Candidatus Aramenus sulfurataquae.
OC   Archaea; Thermoproteota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC   Aramenus.
OX   NCBI_TaxID=1326980 {ECO:0000313|EMBL:EWG07491.1, ECO:0000313|Proteomes:UP000054284};
RN   [1] {ECO:0000313|EMBL:EWG07491.1, ECO:0000313|Proteomes:UP000054284}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AZ1-illumnia {ECO:0000313|EMBL:EWG07491.1};
RX   PubMed=24604657;
RA   Servin-Garciduenas L.E., Martinez-Romero E.;
RT   "Draft Genome Sequence of the Sulfolobales Archaeon AZ1, Obtained through
RT   Metagenomic Analysis of a Mexican Hot Spring.";
RL   Genome Announc. 2:e00164-14(2014).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC         Evidence={ECO:0000256|ARBA:ARBA00001665};
CC   -!- SIMILARITY: Belongs to the HerA family.
CC       {ECO:0000256|ARBA:ARBA00007816}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EWG07491.1}.
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DR   EMBL; ASRH01000003; EWG07491.1; -; Genomic_DNA.
DR   AlphaFoldDB; W7KW21; -.
DR   PATRIC; fig|1326980.6.peg.637; -.
DR   Proteomes; UP000054284; Unassembled WGS sequence.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR018538; HerA_barrel_dom.
DR   InterPro; IPR002789; HerA_central.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   NCBIfam; NF040937; HerA_Thermprot; 1.
DR   PANTHER; PTHR42957; HELICASE MJ1565-RELATED; 1.
DR   PANTHER; PTHR42957:SF1; HELICASE MJ1565-RELATED; 1.
DR   Pfam; PF01935; DUF87; 1.
DR   Pfam; PF09378; HAS-barrel; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000054284}.
FT   DOMAIN          6..85
FT                   /note="Helicase HerA barrel"
FT                   /evidence="ECO:0000259|Pfam:PF09378"
FT   DOMAIN          121..332
FT                   /note="Helicase HerA central"
FT                   /evidence="ECO:0000259|Pfam:PF01935"
SQ   SEQUENCE   495 AA;  55525 MW;  DE73368554DCF768 CRC64;
     MMEQIVGYII GTSTTQQATM LAKQAVRLGR YVTLEYDDQK VLGLITSVTR GSPLINDSLD
     DVEILDDIIF VQKVPRFIRA EIKLLYDLTS NSLPEVPPPP GTQVRFSQES ELQSLFSEGE
     IEIGKLIGTN VAVRIKVNSL ARHLAILAAT GSGKSNTVAV LTERISEIGG SVLIFDYHGE
     YYNSDIKNLN PIEPKLNPRY LSPREFATLL EIPRNATIQY RILRKAFTEY LKDLENSFNS
     GQVDLSKLNE TFVADIESRI EKYLGDSKKN KDSAEEVENK LEEFFERYSN IIDLTAPDIT
     SRIRSHSVNV VDISHLDEDS MDAIVSHYLR RVLDSRKSYK RTGNGLRFPV ILVIEEAHVF
     ISKTENTLTK AWAGKIAREG RKFGVSMVIV SQRPKGLDDT ILSQMTNKII LKIVEPNDKK
     YVLESSDNLS EDLVSQLSSL DVGEAIVIGN LVRIPSFVKI DKFEGKLGGS DPDMIGEWRK
     EEEESKVRSS VADFG
//