ID W7LQD2_GIBM7 Unreviewed; 451 AA.
AC W7LQD2;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=Translation initiation factor eIF2B subunit beta {ECO:0000256|ARBA:ARBA00044122};
DE AltName: Full=eIF2B GDP-GTP exchange factor subunit beta {ECO:0000256|ARBA:ARBA00044228};
GN ORFNames=FVEG_03031 {ECO:0000313|EMBL:EWG40751.1};
OS Gibberella moniliformis (strain M3125 / FGSC 7600) (Maize ear and stalk rot
OS fungus) (Fusarium verticillioides).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium fujikuroi species complex.
OX NCBI_TaxID=334819 {ECO:0000313|EMBL:EWG40751.1, ECO:0000313|Proteomes:UP000009096};
RN [1] {ECO:0000313|EMBL:EWG40751.1, ECO:0000313|Proteomes:UP000009096}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M3125 / FGSC 7600 {ECO:0000313|Proteomes:UP000009096};
RX PubMed=20237561; DOI=10.1038/nature08850;
RA Ma L.J., van der Does H.C., Borkovich K.A., Coleman J.J., Daboussi M.J.,
RA Di Pietro A., Dufresne M., Freitag M., Grabherr M., Henrissat B.,
RA Houterman P.M., Kang S., Shim W.B., Woloshuk C., Xie X., Xu J.R.,
RA Antoniw J., Baker S.E., Bluhm B.H., Breakspear A., Brown D.W.,
RA Butchko R.A., Chapman S., Coulson R., Coutinho P.M., Danchin E.G.,
RA Diener A., Gale L.R., Gardiner D.M., Goff S., Hammond-Kosack K.E.,
RA Hilburn K., Hua-Van A., Jonkers W., Kazan K., Kodira C.D., Koehrsen M.,
RA Kumar L., Lee Y.H., Li L., Manners J.M., Miranda-Saavedra D., Mukherjee M.,
RA Park G., Park J., Park S.Y., Proctor R.H., Regev A., Ruiz-Roldan M.C.,
RA Sain D., Sakthikumar S., Sykes S., Schwartz D.C., Turgeon B.G.,
RA Wapinski I., Yoder O., Young S., Zeng Q., Zhou S., Galagan J., Cuomo C.A.,
RA Kistler H.C., Rep M.;
RT "Comparative genomics reveals mobile pathogenicity chromosomes in
RT Fusarium.";
RL Nature 464:367-373(2010).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC {ECO:0000256|ARBA:ARBA00004514}.
CC -!- SIMILARITY: Belongs to the eIF-2B alpha/beta/delta subunits family.
CC {ECO:0000256|ARBA:ARBA00007251, ECO:0000256|RuleBase:RU003814}.
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DR EMBL; DS022244; EWG40751.1; -; Genomic_DNA.
DR RefSeq; XP_018746942.1; XM_018890599.1.
DR AlphaFoldDB; W7LQD2; -.
DR STRING; 334819.W7LQD2; -.
DR EnsemblFungi; FVEG_03031T0; FVEG_03031T0; FVEG_03031.
DR GeneID; 30061197; -.
DR KEGG; fvr:FVEG_03031; -.
DR VEuPathDB; FungiDB:FVEG_03031; -.
DR eggNOG; KOG1465; Eukaryota.
DR HOGENOM; CLU_016218_4_3_1; -.
DR OMA; SHSCAVA; -.
DR OrthoDB; 169494at2759; -.
DR Proteomes; UP000009096; Chromosome 5.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR InterPro; IPR000649; IF-2B-related.
DR InterPro; IPR042529; IF_2B-like_C.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR PANTHER; PTHR45859; TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT BETA; 1.
DR PANTHER; PTHR45859:SF1; TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT BETA; 1.
DR Pfam; PF01008; IF-2B; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 1.
PE 3: Inferred from homology;
KW Initiation factor {ECO:0000313|EMBL:EWG40751.1};
KW Protein biosynthesis {ECO:0000313|EMBL:EWG40751.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000009096}.
FT REGION 107..170
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 188..209
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 115..153
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 451 AA; 48549 MW; 609222D3B90E2047 CRC64;
MAPVSAGYAP DLEKYLRSLK GQALESSVES LICLLKRRQI KGSEPCAVAT AHILLQVVAR
SKWFNVDSLI DNVSRIGRRL VEAQPKELVI ANIVRRVLGL IRDEAAEDRN EGASETPSDA
QITPTDAVPN PDALSHQWPP STYGKQDSAG DYITNSAKPP PARPGPLSSY SSVNVPKTLF
HLLSVSTPGE LAPSSQGSPL GLSGASTPSW RAPSAQVHAL RSEVIDGIEE IKDEISSVDD
QIAALADVQI HPGDYVLIHQ PSPTVERFIL RAALKRRFTV LIATEPPKKQ TPEVPHASFR
KKLASAGITV INIMNGGLMA YMSRVDKVIL GAHSIVASGG VMADAGATAI ARAAKERGRA
VIVLGGVYKL SPVNPYSGEH LIEWGDSASF VNFADGNMVN SVEVRTALNE MVPPELIDIY
ITNLGTHSRD HLSSLIADHY KTEDVDFFQD E
//
