ID W7LS31_GIBM7 Unreviewed; 582 AA.
AC W7LS31;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=PNPLA domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=FVEG_01563 {ECO:0000313|EMBL:EWG38305.1};
OS Gibberella moniliformis (strain M3125 / FGSC 7600) (Maize ear and stalk rot
OS fungus) (Fusarium verticillioides).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium fujikuroi species complex.
OX NCBI_TaxID=334819 {ECO:0000313|EMBL:EWG38305.1, ECO:0000313|Proteomes:UP000009096};
RN [1] {ECO:0000313|EMBL:EWG38305.1, ECO:0000313|Proteomes:UP000009096}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M3125 / FGSC 7600 {ECO:0000313|Proteomes:UP000009096};
RX PubMed=20237561; DOI=10.1038/nature08850;
RA Ma L.J., van der Does H.C., Borkovich K.A., Coleman J.J., Daboussi M.J.,
RA Di Pietro A., Dufresne M., Freitag M., Grabherr M., Henrissat B.,
RA Houterman P.M., Kang S., Shim W.B., Woloshuk C., Xie X., Xu J.R.,
RA Antoniw J., Baker S.E., Bluhm B.H., Breakspear A., Brown D.W.,
RA Butchko R.A., Chapman S., Coulson R., Coutinho P.M., Danchin E.G.,
RA Diener A., Gale L.R., Gardiner D.M., Goff S., Hammond-Kosack K.E.,
RA Hilburn K., Hua-Van A., Jonkers W., Kazan K., Kodira C.D., Koehrsen M.,
RA Kumar L., Lee Y.H., Li L., Manners J.M., Miranda-Saavedra D., Mukherjee M.,
RA Park G., Park J., Park S.Y., Proctor R.H., Regev A., Ruiz-Roldan M.C.,
RA Sain D., Sakthikumar S., Sykes S., Schwartz D.C., Turgeon B.G.,
RA Wapinski I., Yoder O., Young S., Zeng Q., Zhou S., Galagan J., Cuomo C.A.,
RA Kistler H.C., Rep M.;
RT "Comparative genomics reveals mobile pathogenicity chromosomes in
RT Fusarium.";
RL Nature 464:367-373(2010).
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DR EMBL; DS022243; EWG38305.1; -; Genomic_DNA.
DR RefSeq; XP_018744496.1; XM_018888565.1.
DR AlphaFoldDB; W7LS31; -.
DR STRING; 334819.W7LS31; -.
DR GeneID; 30059844; -.
DR KEGG; fvr:FVEG_01563; -.
DR VEuPathDB; FungiDB:FVEG_01563; -.
DR eggNOG; KOG4231; Eukaryota.
DR OrthoDB; 2093603at2759; -.
DR Proteomes; UP000009096; Chromosome 6.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0046486; P:glycerolipid metabolic process; IEA:UniProt.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-UniRule.
DR CDD; cd07216; Pat17_PNPLA8_PNPLA9_like3; 1.
DR Gene3D; 3.40.1090.10; Cytosolic phospholipase A2 catalytic domain; 1.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR004343; Plus-3_dom.
DR InterPro; IPR002641; PNPLA_dom.
DR PANTHER; PTHR24185; CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA; 1.
DR PANTHER; PTHR24185:SF4; SERINE HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G07870)-RELATED; 1.
DR Pfam; PF01734; Patatin; 1.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR PROSITE; PS51360; PLUS3; 1.
DR PROSITE; PS51635; PNPLA; 1.
PE 4: Predicted;
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Reference proteome {ECO:0000313|Proteomes:UP000009096}.
FT DOMAIN 235..447
FT /note="PNPLA"
FT /evidence="ECO:0000259|PROSITE:PS51635"
FT DOMAIN 543..582
FT /note="Plus3"
FT /evidence="ECO:0000259|PROSITE:PS51360"
SQ SEQUENCE 582 AA; 65234 MW; 596BF11336190BDB CRC64;
MEALKNAEAL PIYPSSSANV LDGKYAVRST ESGHVESHGS EIESNTWFKT PPLDVKTIQR
LHSIQLITES HDQGYCDDRA NGNWTWFEIS ILENANATEP RVKDDVQLTW ESHKNQLESK
DFVQLEGTLF PEDHDIFRLL EDQNVIAVRV CSRFSGWELI AKQGYLVVEF GPPVEREPLR
FGTIAAKVLY TLEAFNDVNE LSFPDLEEFP SLPATTFRAD RMGTEDANER PLRVLSLDGG
GVRGLASLLV LKAIMDRACP GKKPCEVFDM IGGTSTGGLI AIMLGRLEMS VDECIKEYNA
LMGDVFPPPQ KWTWNPWTWD TNGMWMSILS KGEKWKSEDL EKVIKGLVKR VLNQDPEEVL
LQDPKNPNPS CKVFVTASRA EGANNSEPVL LRSYKIKHAM PDLPKVKLWQ AARATSAAPG
YFNSIEIDGM SFIDGGVQAN NPLGWLWNEV LQVFTAVRTT DCFLSIGTGV SLSKQSVSPF
GLVGILTNTN IVNILFRELI NAFAPRGVTK KYWRFDFGDG LPDWVEEDGV MKWVYLAKIE
ATEGEMDDIT ITELLKKKVD EYIQEPGFQK QLADCTVALR RS
//
