ID W7LTM7_GIBM7 Unreviewed; 1484 AA.
AC W7LTM7;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 24-JAN-2024, entry version 40.
DE SubName: Full=CCR4-NOT transcription complex subunit 4 {ECO:0000313|EMBL:EWG41881.1};
GN ORFNames=FVEG_15352 {ECO:0000313|EMBL:EWG41881.1};
OS Gibberella moniliformis (strain M3125 / FGSC 7600) (Maize ear and stalk rot
OS fungus) (Fusarium verticillioides).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium fujikuroi species complex.
OX NCBI_TaxID=334819 {ECO:0000313|EMBL:EWG41881.1, ECO:0000313|Proteomes:UP000009096};
RN [1] {ECO:0000313|EMBL:EWG41881.1, ECO:0000313|Proteomes:UP000009096}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M3125 / FGSC 7600 {ECO:0000313|Proteomes:UP000009096};
RX PubMed=20237561; DOI=10.1038/nature08850;
RA Ma L.J., van der Does H.C., Borkovich K.A., Coleman J.J., Daboussi M.J.,
RA Di Pietro A., Dufresne M., Freitag M., Grabherr M., Henrissat B.,
RA Houterman P.M., Kang S., Shim W.B., Woloshuk C., Xie X., Xu J.R.,
RA Antoniw J., Baker S.E., Bluhm B.H., Breakspear A., Brown D.W.,
RA Butchko R.A., Chapman S., Coulson R., Coutinho P.M., Danchin E.G.,
RA Diener A., Gale L.R., Gardiner D.M., Goff S., Hammond-Kosack K.E.,
RA Hilburn K., Hua-Van A., Jonkers W., Kazan K., Kodira C.D., Koehrsen M.,
RA Kumar L., Lee Y.H., Li L., Manners J.M., Miranda-Saavedra D., Mukherjee M.,
RA Park G., Park J., Park S.Y., Proctor R.H., Regev A., Ruiz-Roldan M.C.,
RA Sain D., Sakthikumar S., Sykes S., Schwartz D.C., Turgeon B.G.,
RA Wapinski I., Yoder O., Young S., Zeng Q., Zhou S., Galagan J., Cuomo C.A.,
RA Kistler H.C., Rep M.;
RT "Comparative genomics reveals mobile pathogenicity chromosomes in
RT Fusarium.";
RL Nature 464:367-373(2010).
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DR EMBL; DS022245; EWG41881.1; -; Genomic_DNA.
DR RefSeq; XP_018748072.1; XM_018904479.1.
DR GeneID; 30072228; -.
DR VEuPathDB; FungiDB:FVEG_15352; -.
DR OrthoDB; 1748at2759; -.
DR Proteomes; UP000009096; Chromosome 2.
DR GO; GO:0030014; C:CCR4-NOT complex; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR CDD; cd16618; mRING-HC-C4C4_CNOT4; 1.
DR CDD; cd12438; RRM_CNOT4; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR034261; CNOT4_RRM.
DR InterPro; IPR039780; Mot2.
DR InterPro; IPR039515; NOT4_mRING-HC-C4C4.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR003954; RRM_dom_euk.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR12603; CCR4-NOT TRANSCRIPTION COMPLEX RELATED; 1.
DR PANTHER; PTHR12603:SF0; CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 4; 1.
DR Pfam; PF00076; RRM_1; 1.
DR Pfam; PF14570; zf-RING_4; 1.
DR SMART; SM00361; RRM_1; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS50102; RRM; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00175};
KW Reference proteome {ECO:0000313|Proteomes:UP000009096};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00175};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00175}.
FT DOMAIN 15..58
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 121..207
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 231..639
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 675..701
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 713..970
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1026..1189
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 82..109
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1447..1474
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 240..331
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 339..357
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 361..382
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 410..449
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 475..524
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 532..605
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 675..689
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 773..787
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 806..821
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 883..902
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 903..966
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1026..1053
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1104..1124
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1127..1142
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1159..1186
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1484 AA; 159324 MW; 8D83364147F6A429 CRC64;
MAPQDSFIED EEDTCPLCIE EFDLSDRNFR PCPCGYQVCQ FCFNNIKNNM NGLCPACRRP
YDEKTIQWKV VTQEEVAEFR ANIQKNQKKR ALDQRQKELQ KREAEKENRK NLIGVRVVQK
NLVYITGLAP TVREDELLKT LRKPEFFGQY GNIQKISISN RKSSDGQHQS LGIYVTFERP
EEATRCIQAV HGSHNGDRVL KAQHGTTKYC SAWLKNEKCG NPGCMFLHEQ GDEEDSYSRQ
DLSSMNSIGS QRPLPGGSSR SASRQQISHP TPPPVVSHSM TRSISKEGSE NGADGSALPS
SANWARNPQR SRRGSLATSG AASSPAISTA QPVTAEPVPE EAVEEEDEDE LEEEEPQQPD
PVAGPSSSRS REPESPAPTQ ESPDTWLKEI YKTLQSCPMP IFPDFDEDQY PPMFDPRGGE
KRRAMREEED SRLTGEQEEQ PEVREPSEGE PETGGSLALG GEPEDRDTSS DNRGFDRRPS
TQPPIQRLST DGLFGPSLTG ASPFGQSSGN PGSRSMTPQQ LYLRSQGGFG DAPPGITSQS
NAFQNQGQSQ GQGHNRQSSR FSFANDNASS STNVKVAANP RIMAQQSSMM PNTFPSQSSN
QFYGASMPGP PPGLKSTGTP PSMFGQFGGQ GFGAPKDNSS ELLQSLIGRG RAGNNQSHDA
GKLDLADPSI LQARMQHQSQ GSAGVGQGLF GGQSQDDELP SLDEATNSVD ALVSDDPILP
PIGLEGRTSV PPGLSLPPGI PANISRPPST QGHAKLTNIV PALPRMPPPG LSQGSLTPDQ
SPAKLNPTTP VLEAKKNIKS LAAESGLSRE ITTQSQPKLA KASFLQDEDF PALDASKNKS
RPATPTSKAT PKAKRHAERI VDRMMAKAGA SLESTTQETN AEETKVQETK AQEVKVKETK
AQEAKPASSS QAADKKPTAV NTQVGKNVAV KTSELSATTE KSTTETSAAF PPLPTASSNA
IASPVTRTAP KTLRVIATPK TEAPPPASPA LTMASVALSG TSRAVSGSYR PDTPASEMIS
DNASVVSASV THSRASSPPP SRIGSAAVRT TTKSQQRKQR KDVLKQETKL IAEAPIAEAE
VHAPIMGRKK KQKKEKPVKA TQPDASTIPE TPTDEPSQPL SQQEPVKVPE RETEEKPAKS
KTSQKKSTKS KGKTKEVETQ PTPPPPASPK ESIPDTQEPP ARPQPDPASV FSEVKNTLWA
SSVDKLQLFK PIANGSSRTD YSAAKNNANK AEHCKDCSCK CGEIQDEDLA ALRAGKPVRK
QFHVDGSRML ITPNGDCVRG LTPEEEDAFL ELQAAIAKTA ENPGSFIAPR HQPGSGAFSL
IKGRAVPNGR PNIFPATAQL QSQDPIGKLQ REDALSYINQ YVLPRLNLGA TNMGFPKGAS
PTKDAAAASL NSLAPYFYGP DAAAGVGIYS PPDGARAMQD FSSAGMSSEE RGKNFGMGVG
GMPLMSVEDA EGALAAARRE TEKLEKGLNQ VIKRNRRLVL GGNN
//
