ID W7LW57_GIBM7 Unreviewed; 1054 AA.
AC W7LW57;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE RecName: Full=CXC domain-containing protein {ECO:0000259|PROSITE:PS51633};
GN ORFNames=FVEG_00666 {ECO:0000313|EMBL:EWG36777.1};
OS Gibberella moniliformis (strain M3125 / FGSC 7600) (Maize ear and stalk rot
OS fungus) (Fusarium verticillioides).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium fujikuroi species complex.
OX NCBI_TaxID=334819 {ECO:0000313|EMBL:EWG36777.1, ECO:0000313|Proteomes:UP000009096};
RN [1] {ECO:0000313|EMBL:EWG36777.1, ECO:0000313|Proteomes:UP000009096}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M3125 / FGSC 7600 {ECO:0000313|Proteomes:UP000009096};
RX PubMed=20237561; DOI=10.1038/nature08850;
RA Ma L.J., van der Does H.C., Borkovich K.A., Coleman J.J., Daboussi M.J.,
RA Di Pietro A., Dufresne M., Freitag M., Grabherr M., Henrissat B.,
RA Houterman P.M., Kang S., Shim W.B., Woloshuk C., Xie X., Xu J.R.,
RA Antoniw J., Baker S.E., Bluhm B.H., Breakspear A., Brown D.W.,
RA Butchko R.A., Chapman S., Coulson R., Coutinho P.M., Danchin E.G.,
RA Diener A., Gale L.R., Gardiner D.M., Goff S., Hammond-Kosack K.E.,
RA Hilburn K., Hua-Van A., Jonkers W., Kazan K., Kodira C.D., Koehrsen M.,
RA Kumar L., Lee Y.H., Li L., Manners J.M., Miranda-Saavedra D., Mukherjee M.,
RA Park G., Park J., Park S.Y., Proctor R.H., Regev A., Ruiz-Roldan M.C.,
RA Sain D., Sakthikumar S., Sykes S., Schwartz D.C., Turgeon B.G.,
RA Wapinski I., Yoder O., Young S., Zeng Q., Zhou S., Galagan J., Cuomo C.A.,
RA Kistler H.C., Rep M.;
RT "Comparative genomics reveals mobile pathogenicity chromosomes in
RT Fusarium.";
RL Nature 464:367-373(2010).
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DR EMBL; DS022242; EWG36777.1; -; Genomic_DNA.
DR RefSeq; XP_018742968.1; XM_018887231.1.
DR AlphaFoldDB; W7LW57; -.
DR STRING; 334819.W7LW57; -.
DR GeneID; 30059014; -.
DR KEGG; fvr:FVEG_00666; -.
DR VEuPathDB; FungiDB:FVEG_00666; -.
DR eggNOG; KOG1079; Eukaryota.
DR OrthoDB; 902834at2759; -.
DR Proteomes; UP000009096; Chromosome 1.
DR GO; GO:0042054; F:histone methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 2.170.270.10; SET domain; 1.
DR InterPro; IPR026489; CXC_dom.
DR InterPro; IPR045318; EZH1/2-like.
DR InterPro; IPR048360; Ezh2-like_CXC_fung.
DR InterPro; IPR040968; Ezh2_MCSS_fung.
DR InterPro; IPR040595; EZH2_N.
DR InterPro; IPR041355; Pre-SET_CXC.
DR InterPro; IPR046341; SET_dom_sf.
DR PANTHER; PTHR45747; HISTONE-LYSINE N-METHYLTRANSFERASE E(Z); 1.
DR PANTHER; PTHR45747:SF4; HISTONE-LYSINE N-METHYLTRANSFERASE E(Z); 1.
DR Pfam; PF21509; Ezh2-like__CXC_fung; 1.
DR Pfam; PF18600; Ezh2_MCSS_fung; 1.
DR Pfam; PF18601; EZH2_N; 1.
DR Pfam; PF18264; preSET_CXC; 1.
DR SUPFAM; SSF82199; SET domain; 1.
DR PROSITE; PS51633; CXC; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000009096};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 605..722
FT /note="CXC"
FT /evidence="ECO:0000259|PROSITE:PS51633"
FT REGION 1..99
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 117..160
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 362..386
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 792..837
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 850..966
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 998..1054
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 32..89
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 117..154
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 367..381
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 792..818
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 891..905
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1023..1045
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1054 AA; 118166 MW; 85345DF381C76101 CRC64;
MASHHLVAIA AGKPDTIDLT GDSDSDYEPD SLGPVNRNNT TTARFTPNFS ISSERPSSTN
APVSPPRLNR STSSIAASQD KQPSASAEPP RPASSVLKLS QKVTTITANS DDAQSMAKLS
SVTASNLASR QVTPTPEKDG SKSAQQSKPA SPKYQTPKKQ EWDVAAVVEK LTQFRQDIKD
GHSRMTSYII ESTKPNERRV MTGKNLFAGL INKPVASKKG ETMRIKSKEH TKLKNNKRED
HYSIVRIQTD EERVPRYRFH HVEIKKNILT PNTMLTFVPH LRDLETSEEY KYNVWLQELE
DIDRKSGFKP MSREEKVRIA VRSEFASTVL LYLGTWLDKL SIPGCNRSAL IRFMASREPD
DAITPRQKSD ILNSHRPAES TTPPEANKAA HMFTEAFRRV FHQGQPPTKQ IELRDVLLLD
ESVDSIMETK PTAKDGSSTQ HENEHDAVEY WLGTYSILGC LICFSHSCEH GEYDAQNCKR
TLSILPRLSD TLKRRRRLPY SAGDAVNGNG PLSPLCKRNC YRSSPRPVAA STQRPWDEED
HFILRSTVVT ADRSKVTKDP FCLVAQLLDR DCSDVFNEFQ KLNVSMSPVE PANRSQIRTV
SWYDRFKKTL IGDWESHTKT HEHQKRELSE PCNHEGPCTS ESCICVQHGV LCEKFCGCTV
ENCAYKFTGC ACHSQGKTCL SKGKERPCIC VQLNRECDPD VCGRCGVVER ADPENADDEV
LHSTGCQNCS LQRGQAKSLA LGESQLEGVG YGLFTIEDIS QDDFIIEYLE RNFFSNYGEN
FPNLTKKLLD HKVEGKSDQV KNRSRRPNGE GVARKNPKTD KKKPGKGKKR AQAVLDEDDM
LVDTLGFAPK PLRKRKKGPF EEDSEEEEYH PTGTDASIME TPSDGDSDFG NSAARLRKRA
RQDGKGAASS HNGKPRGDPK TRGKRGGARP GSGRPRKYPR KLTSAPIIEH PSASESQDRE
DPEERQIVAA DTIVPTALQR PQPMEINDSM EYITFSEERT EESRLLQSQL EEDNDDDDDE
DQDVVVRSRV DRGVRNRRPT AKLRDDGDWL GGSQ
//
