ID W7M1K8_GIBM7 Unreviewed; 2401 AA.
AC W7M1K8;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Myosin heavy chain {ECO:0000313|EMBL:EWG38847.1};
GN ORFNames=FVEG_01943 {ECO:0000313|EMBL:EWG38847.1};
OS Gibberella moniliformis (strain M3125 / FGSC 7600) (Maize ear and stalk rot
OS fungus) (Fusarium verticillioides).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium fujikuroi species complex.
OX NCBI_TaxID=334819 {ECO:0000313|EMBL:EWG38847.1, ECO:0000313|Proteomes:UP000009096};
RN [1] {ECO:0000313|EMBL:EWG38847.1, ECO:0000313|Proteomes:UP000009096}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M3125 / FGSC 7600 {ECO:0000313|Proteomes:UP000009096};
RX PubMed=20237561; DOI=10.1038/nature08850;
RA Ma L.J., van der Does H.C., Borkovich K.A., Coleman J.J., Daboussi M.J.,
RA Di Pietro A., Dufresne M., Freitag M., Grabherr M., Henrissat B.,
RA Houterman P.M., Kang S., Shim W.B., Woloshuk C., Xie X., Xu J.R.,
RA Antoniw J., Baker S.E., Bluhm B.H., Breakspear A., Brown D.W.,
RA Butchko R.A., Chapman S., Coulson R., Coutinho P.M., Danchin E.G.,
RA Diener A., Gale L.R., Gardiner D.M., Goff S., Hammond-Kosack K.E.,
RA Hilburn K., Hua-Van A., Jonkers W., Kazan K., Kodira C.D., Koehrsen M.,
RA Kumar L., Lee Y.H., Li L., Manners J.M., Miranda-Saavedra D., Mukherjee M.,
RA Park G., Park J., Park S.Y., Proctor R.H., Regev A., Ruiz-Roldan M.C.,
RA Sain D., Sakthikumar S., Sykes S., Schwartz D.C., Turgeon B.G.,
RA Wapinski I., Yoder O., Young S., Zeng Q., Zhou S., Galagan J., Cuomo C.A.,
RA Kistler H.C., Rep M.;
RT "Comparative genomics reveals mobile pathogenicity chromosomes in
RT Fusarium.";
RL Nature 464:367-373(2010).
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|ARBA:ARBA00008314,
CC ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR EMBL; DS022243; EWG38847.1; -; Genomic_DNA.
DR RefSeq; XP_018745038.1; XM_018888978.1.
DR SMR; W7M1K8; -.
DR STRING; 334819.W7M1K8; -.
DR GeneID; 30060189; -.
DR KEGG; fvr:FVEG_01943; -.
DR VEuPathDB; FungiDB:FVEG_01943; -.
DR eggNOG; KOG0161; Eukaryota.
DR OrthoDB; 1094820at2759; -.
DR Proteomes; UP000009096; Chromosome 6.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006996; P:organelle organization; IEA:UniProt.
DR CDD; cd01377; MYSc_class_II; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.340; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.30.70.1590; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 2.30.30.360; Myosin S1 fragment, N-terminal; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR Gene3D; 4.10.270.10; Myosin, subunit A; 1.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR004009; Myosin_N.
DR InterPro; IPR008989; Myosin_S1_N.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR45615:SF40; MYOSIN HEAVY CHAIN, MUSCLE-RELATED; 1.
DR PANTHER; PTHR45615; MYOSIN HEAVY CHAIN, NON-MUSCLE; 1.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF02736; Myosin_N; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF90257; Myosin rod fragments; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF57997; Tropomyosin; 1.
DR PROSITE; PS50096; IQ; 1.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51844; SH3_LIKE; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Coiled coil {ECO:0000256|SAM:Coils};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000009096}.
FT DOMAIN 118..168
FT /note="Myosin N-terminal SH3-like"
FT /evidence="ECO:0000259|PROSITE:PS51844"
FT DOMAIN 172..864
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT REGION 1..96
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 743..765
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT REGION 1181..1203
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1628..1648
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2252..2294
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2353..2376
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1712..1739
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1838..2062
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2105..2139
FT /evidence="ECO:0000256|SAM:Coils"
FT BINDING 265..272
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 2401 AA; 275626 MW; CF33EE93F7344974 CRC64;
MSFNANANGT AHRRSNPFAR TTSASPATNT NLRPKSAIFS SPSSTPGLST PSGHSRTQSN
GSLSAITHGF SGSAPRQQRS DSKSGTPTST TFAPSFIKTE EMKRHDTVKG IEGENDFSGK
RYVWLKDPQA AFVRGWIVEE MDGNRLLVQC DDGTQRDVDA ESVDKVNPAK FDKANDMAEL
THLNEASVVH NLHMRYQADL IYTYSGLFLV TVNPYASIPI YSNEYINMYR GRNREDTKPH
IFAMADEAFR NLVEEGKNQS ILVTGESGAG KTENTKKVIQ YLAAVAQADS TIKNKPHHSN
LSQQILRANP ILEAFGNAQT VRNNNSSRFG KFIRIEFTRN GAICGAYIDW YLLEKSRVVH
INPHERNYHV FYQLLKGASS SLKREFLIDG LTVEDFNYTR DGHDTIVGVS DHDEWESLME
AFDVMGFSDE EQRSILRTVA AVLHLGNITV VKESRTADQA RLAPDAKEQA AKVCKLLGVP
LEPFLKGLLH PKVKAGREWV EKVQTPEQVR LGLDALSKGI YERGFGDLVN RINGQLDRTG
MGLEDSHFIG VLDIAGFEIF EQNSFEQLCI NYTNEKLQQF FNHHMFVLEQ EEYAREQIEW
KFIDFGRDLQ PTIDLIELSN PIGVFSCLDE DCVMPKATDK SFTEKLNSLW DKKSTKYRPS
RLGQGFILTH YAAEVEYSTE GWLEKNKDPL NDNITRLLAA SSNKHVASLF SDCAESEEDH
ATGRSRVKRG LFRTVAQKHK EHLHSLMAQL HSTHPHFVRC ILPNHKKKPK QFNNLLVLDQ
LRCNGVLEGI RIARTGFPNR LPFAEFRQRY EVLCQDMPKG YLEGQAAASL MLEKLGLDRA
LYRVGLTKVF FRAGVLAELE EQRDALITQI MSRFQSVARG FIQRRAAYKR LFRTEATRII
QRNFNVYLDL AENPWWQLIV KMKPLLGTTR TATEVKRRDA MIKDLNERMQ LESQNRMKLE
EERRNCHAEM VRIQQTLESE RALALDKEEI FKRLQLREAE LEEKLAGAIE DQERLEDELD
DLLNAKNRAE RDIETYRSQL EQAATLIAKL EEEKKGLSTK ISEVEQSMAD ITQRQAERSE
QELALQDEIK MLQSQLSVKE RKVQDLETKL VKLDQDSELK LNAAQRELQS TKFRETQLTH
ENEDIQRQLN ELSKTSTDYE DLVRQKESEL ALLRTDNKNF ESERQSLEDQ KKSLTTEKEK
NAEKYREAQA ELVAMKSRQS QLEREAEDAK HLLEARLSED AQADQNRQVL ESQIKDLKDE
LYKTQMDLSR ERQSRDDVQL LGEHRYQELK DEFDRLNESK IIIEKELYAQ QDTLRRTMEA
RTTAEKERDE ARQEIRRLRV AKTQAEEARM QAEVAGERQA SKAALDRENS LRKDLDAAQE
RLQWFEGECA KLNHQIEDLN KLILESGEFG LKNDQAKERL ERELTTVKSR LTASENDNRA
LLNKLQQKGL EIARSSSRAS EASRGQIISL QREKARLEEQ NTKLNKQLGD SQLAIASLEK
RAEKLQLSLE DLSHEVAREV KSSRNAEKAT STFTAQLAEA NRTIESERQL RTQAQTTIRT
LQTSVDTRDK EVNELRAQML DVLRTVDPEV PIPPQSDGAD ENILIQNFDL VRKVEELQQN
LRVQTAARTN AENQLSEMRA SRNDPASRPK LEEIQLNEAP FQGSPTQKRA AKLHARNYSN
TSTPTRRFQD LDHLQDSTRS DRTIDTLNFN NRMDLKAEVE ELQNQLQLKE MQNRHLQSQI
NRSTPIPENY DDQSPSLRRI QKLEMVNTRL HEMLDDSNKK VSALERTIRS GQLSLRDVQT
RTHEEILEVL NSQEDSRRAL VHSHKDAVAE LTDIKGHFER LRHDRAKAEV ELRDVKSDLQ
EMTLAREQEA QNRNQLLQEF ADLQIRLDAE TSKFADVSSS LEMYKSRADE YFSKLEQAEI
AVLKASRAEQ FAKSQAKEAE DTYAEVMAER EKMDASIEDL QRQNQRLEEK VEDISTDLAA
ATQAKKRLQH ELEDYRNQRA MEIEDKESSM EQTRKKYQAE FATLTNELDL AREERLFKQA
EIARLREELD ELRSKWDDEV LNSSTWSKEK ARLESTLADV ASSRDEAVNA HNEAQGKVVT
LLSQVRTLRS SVDEITAERD HLLREKRNVE ARLEEAKSGL EDLVKGDSPS LRNAANMDKE
ILELRSHLAQ QEDIAAAAVE KMRRAEALVT EVQKDVMVER ENSIQLQQQK ASLEKVLNEA
QLKLVDLETK GYSSASQDVK FLHKRIQELE SQLEDQETER SKSQRSVRNV DRIVKDMQGQ
IDRKDKQNTQ LSEDVSRMRD KVEKLLKTIE ELQSSESQNQ LSARRAEREL REEKEKIARL
ERELAGLKNL RNDKGSGSVM GSVRSRMGPW RVSEGDDASM VDIPRRKSSL SRVPSFTKGF
L
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