ID W7MCS7_GIBM7 Unreviewed; 403 AA.
AC W7MCS7;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=O-methyltransferase domain-containing protein {ECO:0000259|Pfam:PF00891};
GN ORFNames=FVEG_08892 {ECO:0000313|EMBL:EWG49328.1};
OS Gibberella moniliformis (strain M3125 / FGSC 7600) (Maize ear and stalk rot
OS fungus) (Fusarium verticillioides).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium fujikuroi species complex.
OX NCBI_TaxID=334819 {ECO:0000313|EMBL:EWG49328.1, ECO:0000313|Proteomes:UP000009096};
RN [1] {ECO:0000313|EMBL:EWG49328.1, ECO:0000313|Proteomes:UP000009096}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M3125 / FGSC 7600 {ECO:0000313|Proteomes:UP000009096};
RX PubMed=20237561; DOI=10.1038/nature08850;
RA Ma L.J., van der Does H.C., Borkovich K.A., Coleman J.J., Daboussi M.J.,
RA Di Pietro A., Dufresne M., Freitag M., Grabherr M., Henrissat B.,
RA Houterman P.M., Kang S., Shim W.B., Woloshuk C., Xie X., Xu J.R.,
RA Antoniw J., Baker S.E., Bluhm B.H., Breakspear A., Brown D.W.,
RA Butchko R.A., Chapman S., Coulson R., Coutinho P.M., Danchin E.G.,
RA Diener A., Gale L.R., Gardiner D.M., Goff S., Hammond-Kosack K.E.,
RA Hilburn K., Hua-Van A., Jonkers W., Kazan K., Kodira C.D., Koehrsen M.,
RA Kumar L., Lee Y.H., Li L., Manners J.M., Miranda-Saavedra D., Mukherjee M.,
RA Park G., Park J., Park S.Y., Proctor R.H., Regev A., Ruiz-Roldan M.C.,
RA Sain D., Sakthikumar S., Sykes S., Schwartz D.C., Turgeon B.G.,
RA Wapinski I., Yoder O., Young S., Zeng Q., Zhou S., Galagan J., Cuomo C.A.,
RA Kistler H.C., Rep M.;
RT "Comparative genomics reveals mobile pathogenicity chromosomes in
RT Fusarium.";
RL Nature 464:367-373(2010).
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DR EMBL; DS022252; EWG49328.1; -; Genomic_DNA.
DR RefSeq; XP_018755519.1; XM_018897774.1.
DR AlphaFoldDB; W7MCS7; -.
DR EnsemblFungi; FVEG_08892T0; FVEG_08892T0; FVEG_08892.
DR GeneID; 30066588; -.
DR KEGG; fvr:FVEG_08892; -.
DR VEuPathDB; FungiDB:FVEG_08892; -.
DR eggNOG; KOG3178; Eukaryota.
DR HOGENOM; CLU_005533_5_2_1; -.
DR OMA; SCIAIRK; -.
DR OrthoDB; 1067404at2759; -.
DR Proteomes; UP000009096; Chromosome 10.
DR GO; GO:0008171; F:O-methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR016461; COMT-like.
DR InterPro; IPR001077; O_MeTrfase_dom.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR43712:SF2; O-METHYLTRANSFERASE CICE; 1.
DR PANTHER; PTHR43712; PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED; 1.
DR Pfam; PF00891; Methyltransf_2; 1.
DR PIRSF; PIRSF005739; O-mtase; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51683; SAM_OMT_II; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000009096};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022603}.
FT DOMAIN 234..379
FT /note="O-methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00891"
FT ACT_SITE 307
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR005739-1"
SQ SEQUENCE 403 AA; 45836 MW; 2B4ED62DB85B4F77 CRC64;
MVHPKAEKAL EEAKKLVAQL ESYEDDPISH QNVLKQSEVV RSAFQDPMDQ MTHLMEQFSL
GCAFHTILGI RAYHAMPEDG SPIAAEELAR ITNVATTVIQ RIYRVAVSHG VFVETAPDTY
AHNDLSRILN PRGLGSFFMI VLEFSRAWMH LPEYLESHNP EDVFDLRKSP AVYSVGKEHL
GKSYYELLEM DPDPERRELW NANMVAVDEL MPVVGMFPFA SLKDEVAQDP ERPFLVDIGA
GRGQSCIAIR KDIGDAFDAK YILQDLPGVI DSMDPKHYPD FELMTYDAFT PQPVKNARIY
FMRRFLHDFY TPVCIEFVKN TASAMGPDSR LIICDQLIPD MVEKDKFTDL YWLDFALLAM
TGQEKKKADF EEIFEAAGLE LVKIYPSAYG CTAMLEARLK KPE
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