ID W7MJD0_GIBM7 Unreviewed; 1585 AA.
AC W7MJD0;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE RecName: Full=Myosin MYO2 {ECO:0008006|Google:ProtNLM};
GN ORFNames=FVEG_07789 {ECO:0000313|EMBL:EWG47745.1};
OS Gibberella moniliformis (strain M3125 / FGSC 7600) (Maize ear and stalk rot
OS fungus) (Fusarium verticillioides).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium fujikuroi species complex.
OX NCBI_TaxID=334819 {ECO:0000313|EMBL:EWG47745.1, ECO:0000313|Proteomes:UP000009096};
RN [1] {ECO:0000313|EMBL:EWG47745.1, ECO:0000313|Proteomes:UP000009096}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M3125 / FGSC 7600 {ECO:0000313|Proteomes:UP000009096};
RX PubMed=20237561; DOI=10.1038/nature08850;
RA Ma L.J., van der Does H.C., Borkovich K.A., Coleman J.J., Daboussi M.J.,
RA Di Pietro A., Dufresne M., Freitag M., Grabherr M., Henrissat B.,
RA Houterman P.M., Kang S., Shim W.B., Woloshuk C., Xie X., Xu J.R.,
RA Antoniw J., Baker S.E., Bluhm B.H., Breakspear A., Brown D.W.,
RA Butchko R.A., Chapman S., Coulson R., Coutinho P.M., Danchin E.G.,
RA Diener A., Gale L.R., Gardiner D.M., Goff S., Hammond-Kosack K.E.,
RA Hilburn K., Hua-Van A., Jonkers W., Kazan K., Kodira C.D., Koehrsen M.,
RA Kumar L., Lee Y.H., Li L., Manners J.M., Miranda-Saavedra D., Mukherjee M.,
RA Park G., Park J., Park S.Y., Proctor R.H., Regev A., Ruiz-Roldan M.C.,
RA Sain D., Sakthikumar S., Sykes S., Schwartz D.C., Turgeon B.G.,
RA Wapinski I., Yoder O., Young S., Zeng Q., Zhou S., Galagan J., Cuomo C.A.,
RA Kistler H.C., Rep M.;
RT "Comparative genomics reveals mobile pathogenicity chromosomes in
RT Fusarium.";
RL Nature 464:367-373(2010).
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR EMBL; DS022251; EWG47745.1; -; Genomic_DNA.
DR RefSeq; XP_018753936.1; XM_018896462.1.
DR STRING; 334819.W7MJD0; -.
DR EnsemblFungi; FVEG_07789T0; FVEG_07789T0; FVEG_07789.
DR GeneID; 30065561; -.
DR KEGG; fvr:FVEG_07789; -.
DR VEuPathDB; FungiDB:FVEG_07789; -.
DR eggNOG; KOG0160; Eukaryota.
DR HOGENOM; CLU_000192_3_1_1; -.
DR OMA; EIMFDDR; -.
DR OrthoDB; 1094820at2759; -.
DR Proteomes; UP000009096; Chromosome 3.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006996; P:organelle organization; IEA:UniProt.
DR CDD; cd15480; fMyo2p_CBD; 1.
DR CDD; cd01380; MYSc_Myo5; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.190; -; 3.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.30.70.1590; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR InterPro; IPR002710; Dilute_dom.
DR InterPro; IPR046943; Fungal_Myo2/2A_CBD.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR004009; Myosin_N.
DR InterPro; IPR036103; MYSc_Myo5.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13140; MYOSIN; 1.
DR PANTHER; PTHR13140:SF706; MYOSIN-11; 1.
DR Pfam; PF01843; DIL; 1.
DR Pfam; PF00612; IQ; 3.
DR Pfam; PF00063; Myosin_head; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM01132; DIL; 1.
DR SMART; SM00015; IQ; 5.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF50084; Myosin S1 fragment, N-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51126; DILUTE; 1.
DR PROSITE; PS50096; IQ; 3.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51844; SH3_LIKE; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000009096}.
FT DOMAIN 6..61
FT /note="Myosin N-terminal SH3-like"
FT /evidence="ECO:0000259|PROSITE:PS51844"
FT DOMAIN 74..781
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT DOMAIN 1228..1497
FT /note="Dilute"
FT /evidence="ECO:0000259|PROSITE:PS51126"
FT REGION 188..208
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 656..678
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT REGION 1030..1060
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1107..1129
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1559..1585
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 168..175
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1585 AA; 180545 MW; 8464F90FAE6B4728 CRC64;
MASAYEVGTR AWQPDTAEGW VASELINKTV DGSKVKLTFQ LENGDTKDIE VTAEALQSGN
DPSLPPLMNP TMLEASDDLT NLSHLNEPAV LQAIRLRYLQ KEIYTYSGIV LIATNPFARV
DSLYVPGMVQ VYAGRQRATQ APHLFAIAEE AFMDMVRDKK NQTVVVSGES GAGKTVSAKY
IMRYFATRES PDNPGGRSKR GAESMSETEE QILATNPIME AFGNAKTTRN DNSSRFGKYI
EIMFDEHTNI IGAKIRTYLL ERSRLVFQPL KERNYHIFYQ LVAGASEQQR EELNLLPIEE
FEYLNQGNCP TIDGVDDKAE FEATKKSLST IGVTDAQQAD IFKLLAGLLH LGNVKITASR
NDSVLAPNEP SLERACAILG VKAEEFARWI VKKQLVTRGE KITSNLSQAQ AIVVRDSVAK
FIYSSLFDWL VDIINHSLAA EEVLNRVVSF IGVLDIYGFE HFAKNSFEQF CINYANEKLQ
QEFNQHVFKL EQEEYLREEI DWTFIDFSDN QPCIDLIEGR MGILSLLDEE SRLPMGSDEQ
FVTKLHHNFT PDKHKFYKKP RFGKSAFTVC HYAIDVTYES EGFIEKNRDT VPDEHMAVLR
ATSNEFLKTV LDAASAVREK DAASSSSSSV KPAAGRKIGV AVNRKPTLGG IFRSSLIELM
STINNTDVHY IRCIKPNEAK EAWKFEGPMV LSQLRACGVL ETVRISCAGY PTRWTYEEFA
LRYYMLVKSD QWTSEIREMA DAILKKALGT SSSKGMDKYQ LGLTKIFFRA GMLAFLENLR
TTRLNDCAIM IQKNLRAKYY RRRYLDAREA IVMTQSAIRS WKARKQVQEL RTIRAATTIQ
RVWKGSKQRK AYQQIRKDMV LFESAAKGYL RRKNIMEERL GNAALKIQRS WRSRRQLRAW
RQYRNKVVLI QSLWRGRSAR KDYKKIREEA RDLKQISYKL ENKVVELTQS LGSMKEKNKG
LASQVENYEG QIKSWKKRHN DLEARTKELQ TEANQAGIAV ARLQAMEDEM KKLQIAFDES
TANIKRMQEE ERELRESLRA TNSELETARR SSTQHEKDNM SLRQELESLR DALELARRNA
PINGELANGT TPAAAAPSGL INLVSSKKPK RRSAGAEPRE LDRFSGTYNP RPVSMAVTGT
AHRQNLSGST FLPGVDNIEM ELETLLADED GLNEEVTMGL IRNLKIPSPS STPPPSDKEV
LFPSYLINLV TSEMWNNGFV KESERFLANV MQSIQQEVMQ HDGDEAINPG AFWLSNVHEM
LSFVFLAEDW YEAQKSDNYE YDRLLEIVKH DLESLEFNIY HTWMKVLKKK LHKMIIPAII
ESQSLPGFVT NESSRFLGKL LQSNSTPAYS MDNLLSLLNS VFRAMKAYYL EDSIITQTIT
ELLRLVGVTA FNDLLMRRNF LSWKRGLQIN YNITRIEEWC KSHDMPEGTL QLEHLMQATK
LLQLKKATLN DIEIIQDICW MLSPNQIQKL LNQYLVADYE QPINGEIMKA VASRVTEKSD
VLLLQAVDMD DSGPYEIAEP RVITALETYT PSWLQTPRLK RLAEIVSAQA IAQQEKFDYT
DGEDYEDGQP QHHELAGVDE VETES
//
