ID   W7MJX8_GIBM7            Unreviewed;      1260 AA.
AC   W7MJX8;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   RecName: Full=Nucleoside phosphorylase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=FVEG_10590 {ECO:0000313|EMBL:EWG51688.1};
OS   Gibberella moniliformis (strain M3125 / FGSC 7600) (Maize ear and stalk rot
OS   fungus) (Fusarium verticillioides).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC   Fusarium fujikuroi species complex.
OX   NCBI_TaxID=334819 {ECO:0000313|EMBL:EWG51688.1, ECO:0000313|Proteomes:UP000009096};
RN   [1] {ECO:0000313|EMBL:EWG51688.1, ECO:0000313|Proteomes:UP000009096}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=M3125 / FGSC 7600 {ECO:0000313|Proteomes:UP000009096};
RX   PubMed=20237561; DOI=10.1038/nature08850;
RA   Ma L.J., van der Does H.C., Borkovich K.A., Coleman J.J., Daboussi M.J.,
RA   Di Pietro A., Dufresne M., Freitag M., Grabherr M., Henrissat B.,
RA   Houterman P.M., Kang S., Shim W.B., Woloshuk C., Xie X., Xu J.R.,
RA   Antoniw J., Baker S.E., Bluhm B.H., Breakspear A., Brown D.W.,
RA   Butchko R.A., Chapman S., Coulson R., Coutinho P.M., Danchin E.G.,
RA   Diener A., Gale L.R., Gardiner D.M., Goff S., Hammond-Kosack K.E.,
RA   Hilburn K., Hua-Van A., Jonkers W., Kazan K., Kodira C.D., Koehrsen M.,
RA   Kumar L., Lee Y.H., Li L., Manners J.M., Miranda-Saavedra D., Mukherjee M.,
RA   Park G., Park J., Park S.Y., Proctor R.H., Regev A., Ruiz-Roldan M.C.,
RA   Sain D., Sakthikumar S., Sykes S., Schwartz D.C., Turgeon B.G.,
RA   Wapinski I., Yoder O., Young S., Zeng Q., Zhou S., Galagan J., Cuomo C.A.,
RA   Kistler H.C., Rep M.;
RT   "Comparative genomics reveals mobile pathogenicity chromosomes in
RT   Fusarium.";
RL   Nature 464:367-373(2010).
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DR   EMBL; DS022256; EWG51688.1; -; Genomic_DNA.
DR   RefSeq; XP_018757879.1; XM_018899753.1.
DR   AlphaFoldDB; W7MJX8; -.
DR   STRING; 334819.W7MJX8; -.
DR   GeneID; 30068168; -.
DR   KEGG; fvr:FVEG_10590; -.
DR   VEuPathDB; FungiDB:FVEG_10590; -.
DR   OrthoDB; 2106729at2759; -.
DR   Proteomes; UP000009096; Chromosome 11.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0009116; P:nucleoside metabolic process; IEA:InterPro.
DR   Gene3D; 3.40.50.1580; Nucleoside phosphorylase domain; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR000845; Nucleoside_phosphorylase_d.
DR   InterPro; IPR035994; Nucleoside_phosphorylase_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR46082:SF6; AAA+ ATPASE DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR   PANTHER; PTHR46082; ATP/GTP-BINDING PROTEIN-RELATED; 1.
DR   Pfam; PF05729; NACHT; 1.
DR   Pfam; PF01048; PNP_UDP_1; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF53167; Purine and uridine phosphorylases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000009096}.
FT   DOMAIN          17..324
FT                   /note="Nucleoside phosphorylase"
FT                   /evidence="ECO:0000259|Pfam:PF01048"
FT   DOMAIN          507..684
FT                   /note="NACHT"
FT                   /evidence="ECO:0000259|Pfam:PF05729"
FT   REGION          396..489
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        421..445
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        469..488
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1260 AA;  143005 MW;  DA18151D2B51032E CRC64;
     MDPWRPNRPE KRDDFEVAII CALTLEADAI IALFDYHWED DGLSYGKARG DPNAYSTGVM
     GQHNVVLAHL PGMGKVSAGN IAAFCRMSFP NIKLALLVGI CGGAPYDNKS KSQICLGDVV
     ISTGIVQYDF GRRFPDKFEI KDSLNDIPGR PNVEIRNLLS KLMTARESER LRTESWKYLN
     ELCQDVKRPA VFPGRSKDLL FPVHYRHKHQ DSLTCMTCAS CHHESDPVCD IAPTSSCDQL
     GCDTSRCLQR ANREEDGLHP LIHYGVFATG DTVMKSARDR DHITKKTQAL GFEMESVGVW
     EVFPCVVIKS VSDYADSHKT KDWQPYAAAC AASYAKGFLR YWDSNRKEES VSEPEQFRKR
     IIQSLSYSDM NERRNNISSE APSTFNWIFE ESVEDPVEQD LEWPSSQDSE TNRHPETEWE
     TDTTSDEESG QEESLEDDEG DEAGWETTSD EKSGEEESPE VGDDTDAGWG TESDERSDTL
     EDSTPSHRQQ RNWDSFVDWL KSDLPVYWIT GKPGSGKSTL MKYLISDSRT PAALKKWKKD
     AIIIAHFFWK PGSTMQHSFK GFLCSLVRLI LTSDKSISNS SLQRMITDED GKYSPSDWDP
     RELKNLLLHY RNHSSQPICI FIDALDEISP EQDTLDTLQM LGALISPTIK LCVSSRPERL
     FRLHLQDKPR LEIHELTAQD IEQYSKVSIR SSILQEPQGL KASDLARRIR EMSEGVFLWA
     VLVTRSLIRG INNGDSNTDI DRRLNSTPRD LMDLYRDILL RSAIDRDIYQ QSVSLIFSLV
     FAVKSIPMSL FELMMATDGR LLDQFVVQQK SIIVQDLETK RLRMMNTLEA GCAGLLDLNG
     NIQDSPADSG LEALISGLEM RLYFIHRSAE EFLLDTEEGR KLWESCPCSR AELLIRRTKA
     SLAWFELYTS LNIESRMRRC TILDLNYTLD LWMDVASLPD EVSASTLNLA QRMYERGSIL
     PPMKHAYDDL IVSRSHRSQI SFYAATYDLF ALAKQNLATL PDSESHETAY CIFYYSCTRV
     HEPDDDGNML EDHDVIQIML NDGYNPNWPG ISETSTCKFG SPWLRYLLSL YGELSHNPED
     ILNSTQALTV LDTIRMFLNS GASVHSRFKT VFMWSGSGIG GSYAGFRLAP FWCHAAEASV
     ESSSHEFLVL EINAKVLLES ILVQVHRVIR HASRLKVPEA APHMKALAFG NYEKSYFIVD
     ADWMSDLLVE GVKLWFQHGL KKHDGKKLNS KVMTICSYAT EKARESCRRG PWPFELSYDS
//