ID W7MNW1_GIBM7 Unreviewed; 499 AA.
AC W7MNW1;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=Regulator of G protein signaling-like protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=FVEG_08855 {ECO:0000313|EMBL:EWG49280.1};
OS Gibberella moniliformis (strain M3125 / FGSC 7600) (Maize ear and stalk rot
OS fungus) (Fusarium verticillioides).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium fujikuroi species complex.
OX NCBI_TaxID=334819 {ECO:0000313|EMBL:EWG49280.1, ECO:0000313|Proteomes:UP000009096};
RN [1] {ECO:0000313|EMBL:EWG49280.1, ECO:0000313|Proteomes:UP000009096}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M3125 / FGSC 7600 {ECO:0000313|Proteomes:UP000009096};
RX PubMed=20237561; DOI=10.1038/nature08850;
RA Ma L.J., van der Does H.C., Borkovich K.A., Coleman J.J., Daboussi M.J.,
RA Di Pietro A., Dufresne M., Freitag M., Grabherr M., Henrissat B.,
RA Houterman P.M., Kang S., Shim W.B., Woloshuk C., Xie X., Xu J.R.,
RA Antoniw J., Baker S.E., Bluhm B.H., Breakspear A., Brown D.W.,
RA Butchko R.A., Chapman S., Coulson R., Coutinho P.M., Danchin E.G.,
RA Diener A., Gale L.R., Gardiner D.M., Goff S., Hammond-Kosack K.E.,
RA Hilburn K., Hua-Van A., Jonkers W., Kazan K., Kodira C.D., Koehrsen M.,
RA Kumar L., Lee Y.H., Li L., Manners J.M., Miranda-Saavedra D., Mukherjee M.,
RA Park G., Park J., Park S.Y., Proctor R.H., Regev A., Ruiz-Roldan M.C.,
RA Sain D., Sakthikumar S., Sykes S., Schwartz D.C., Turgeon B.G.,
RA Wapinski I., Yoder O., Young S., Zeng Q., Zhou S., Galagan J., Cuomo C.A.,
RA Kistler H.C., Rep M.;
RT "Comparative genomics reveals mobile pathogenicity chromosomes in
RT Fusarium.";
RL Nature 464:367-373(2010).
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DR EMBL; DS022252; EWG49280.1; -; Genomic_DNA.
DR RefSeq; XP_018755471.1; XM_018897736.1.
DR AlphaFoldDB; W7MNW1; -.
DR STRING; 334819.W7MNW1; -.
DR GeneID; 30066553; -.
DR KEGG; fvr:FVEG_08855; -.
DR VEuPathDB; FungiDB:FVEG_08855; -.
DR eggNOG; KOG3589; Eukaryota.
DR OrthoDB; 1364107at2759; -.
DR PHI-base; PHI:2460; -.
DR Proteomes; UP000009096; Chromosome 10.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.
DR CDD; cd04450; DEP_RGS7-like; 1.
DR Gene3D; 1.10.167.10; Regulator of G-protein Signalling 4, domain 2; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR000591; DEP_dom.
DR InterPro; IPR016137; RGS.
DR InterPro; IPR036305; RGS_sf.
DR InterPro; IPR044926; RGS_subdomain_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR10845; REGULATOR OF G PROTEIN SIGNALING; 1.
DR PANTHER; PTHR10845:SF192; RGS DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR Pfam; PF00610; DEP; 1.
DR Pfam; PF00615; RGS; 1.
DR SMART; SM00049; DEP; 2.
DR SMART; SM00315; RGS; 1.
DR SUPFAM; SSF48097; Regulator of G-protein signaling, RGS; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 2.
DR PROSITE; PS50186; DEP; 1.
DR PROSITE; PS50132; RGS; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000009096};
KW Signal transduction inhibitor {ECO:0000256|ARBA:ARBA00022700}.
FT DOMAIN 227..313
FT /note="DEP"
FT /evidence="ECO:0000259|PROSITE:PS50186"
FT DOMAIN 349..486
FT /note="RGS"
FT /evidence="ECO:0000259|PROSITE:PS50132"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 320..343
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8..25
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 499 AA; 55410 MW; 983194F6EC9033E4 CRC64;
MLDLGGSTTL QRRASTQVPS MSKGTITQSS SRLLCASNDD RPQSKDLQDL FSALLASLLP
LIPHRVRFIK IEHTFLAEDA IHNLGNLKLT QSNRMPDPSN PSGTVVSTST TTFSMNKNTA
RNLCQQFVDA RYIESADGKP DQVFQQRGGV WRPTSKGIMI FDWFCQSNGL YQDQLSELHC
LITGPLLHLE RDVKTDKCHV DRATTEVVFC RLIGVDGRGK KGPYSEGAVG IRLQPERKVN
GKTYHDTCTG QVIAEWLRDN TTCADLREAV NIATHFVHYN LIESVTTDMA YMNQFAACKL
FQPTPIAIYQ LSQRGQDLVE TSSSSRCSSQ GKTDSSSAKG GVNESNRHKL EKILLDPTLR
LLFRENLRET YCEESLAFYE QADEIIRDSK AMLETMVKDK KGDDAANELL SQAHVVFNTF
LAPGSPREVN VNHKIRSSLA QRMTKAQALD ATVADTLQEV TSLLETAQDA VFKLMATDSV
PKFLNNPAAE SRLVQAGVR
//
