ID W7MRY0_GIBM7 Unreviewed; 413 AA.
AC W7MRY0;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Carboxypeptidase A4 {ECO:0000313|EMBL:EWG53856.1};
GN ORFNames=FVEG_12194 {ECO:0000313|EMBL:EWG53856.1};
OS Gibberella moniliformis (strain M3125 / FGSC 7600) (Maize ear and stalk rot
OS fungus) (Fusarium verticillioides).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium fujikuroi species complex.
OX NCBI_TaxID=334819 {ECO:0000313|EMBL:EWG53856.1, ECO:0000313|Proteomes:UP000009096};
RN [1] {ECO:0000313|EMBL:EWG53856.1, ECO:0000313|Proteomes:UP000009096}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M3125 / FGSC 7600 {ECO:0000313|Proteomes:UP000009096};
RX PubMed=20237561; DOI=10.1038/nature08850;
RA Ma L.J., van der Does H.C., Borkovich K.A., Coleman J.J., Daboussi M.J.,
RA Di Pietro A., Dufresne M., Freitag M., Grabherr M., Henrissat B.,
RA Houterman P.M., Kang S., Shim W.B., Woloshuk C., Xie X., Xu J.R.,
RA Antoniw J., Baker S.E., Bluhm B.H., Breakspear A., Brown D.W.,
RA Butchko R.A., Chapman S., Coulson R., Coutinho P.M., Danchin E.G.,
RA Diener A., Gale L.R., Gardiner D.M., Goff S., Hammond-Kosack K.E.,
RA Hilburn K., Hua-Van A., Jonkers W., Kazan K., Kodira C.D., Koehrsen M.,
RA Kumar L., Lee Y.H., Li L., Manners J.M., Miranda-Saavedra D., Mukherjee M.,
RA Park G., Park J., Park S.Y., Proctor R.H., Regev A., Ruiz-Roldan M.C.,
RA Sain D., Sakthikumar S., Sykes S., Schwartz D.C., Turgeon B.G.,
RA Wapinski I., Yoder O., Young S., Zeng Q., Zhou S., Galagan J., Cuomo C.A.,
RA Kistler H.C., Rep M.;
RT "Comparative genomics reveals mobile pathogenicity chromosomes in
RT Fusarium.";
RL Nature 464:367-373(2010).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: Belongs to the peptidase M14 family.
CC {ECO:0000256|ARBA:ARBA00005988}.
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DR EMBL; DS022260; EWG53856.1; -; Genomic_DNA.
DR RefSeq; XP_018760047.1; XM_018901546.1.
DR AlphaFoldDB; W7MRY0; -.
DR MEROPS; M14.014; -.
DR EnsemblFungi; FVEG_12194T0; FVEG_12194T0; FVEG_12194.
DR GeneID; 30069657; -.
DR KEGG; fvr:FVEG_12194; -.
DR VEuPathDB; FungiDB:FVEG_12194; -.
DR eggNOG; KOG2650; Eukaryota.
DR HOGENOM; CLU_019326_1_1_1; -.
DR OMA; YDFTWKK; -.
DR OrthoDB; 3540647at2759; -.
DR Proteomes; UP000009096; Chromosome 4.
DR GO; GO:0004181; F:metallocarboxypeptidase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR CDD; cd03860; M14_CP_A-B_like; 1.
DR Gene3D; 3.40.630.10; Zn peptidases; 1.
DR InterPro; IPR000834; Peptidase_M14.
DR PANTHER; PTHR11705:SF91; CARBOXYPEPTIDASE A1 (PANCREATIC)-RELATED; 1.
DR PANTHER; PTHR11705; PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B; 1.
DR Pfam; PF00246; Peptidase_M14; 1.
DR PRINTS; PR00765; CRBOXYPTASEA.
DR SMART; SM00631; Zn_pept; 1.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
DR PROSITE; PS00132; CARBOXYPEPT_ZN_1; 1.
PE 3: Inferred from homology;
KW Carboxypeptidase {ECO:0000313|EMBL:EWG53856.1};
KW Hydrolase {ECO:0000313|EMBL:EWG53856.1};
KW Protease {ECO:0000313|EMBL:EWG53856.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000009096};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..15
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 16..413
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012204096"
FT DOMAIN 163..185
FT /note="Peptidase M14 carboxypeptidase A"
FT /evidence="ECO:0000259|PROSITE:PS00132"
SQ SEQUENCE 413 AA; 44827 MW; B437258A480C479B CRC64;
MRSSLLLALL PLAIATAVPS SKKVDYNGFK SLRVTLPKGA KNAVAEINKL SATILNPGAK
EELDIVVSPD NIDAVTKIAS DTTVLVEDVG AALAEEETSE IYAVPSESWF TAYHSYADHL
QFLKDLQSSF PSQSEIVTLG NSFQGRALTG IHIWGSGGKG SKPAIVFHGT VHAREWIATM
TAEYMAYQLL TKYSSDSAVK AIVDKFDFYI TPVVNPDGFV YTQTTNRLWR KNRQTVSGNS
CVGRDINRNW PYKWELTGGA STNPCDETYK GQAAGDSPEL KAIKGQIDSL AAGKGITFYV
DFHSYGQYVL WPYGYDCSFV APEEAALKTV GTRITNAIRS NSGQTYTAGN SCRALYATTG
DSLDYIQGVA KAKYSYTIEL RDRGTYGFSL PASQIQATVR ETWAGIVAGL TGL
//
