ID W7MU76_GIBM7 Unreviewed; 1179 AA.
AC W7MU76;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Helicase required for RNAi-mediated heterochromatin assembly 1 {ECO:0008006|Google:ProtNLM};
GN ORFNames=FVEG_13112 {ECO:0000313|EMBL:EWG55058.1};
OS Gibberella moniliformis (strain M3125 / FGSC 7600) (Maize ear and stalk rot
OS fungus) (Fusarium verticillioides).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium fujikuroi species complex.
OX NCBI_TaxID=334819 {ECO:0000313|EMBL:EWG55058.1, ECO:0000313|Proteomes:UP000009096};
RN [1] {ECO:0000313|EMBL:EWG55058.1, ECO:0000313|Proteomes:UP000009096}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M3125 / FGSC 7600 {ECO:0000313|Proteomes:UP000009096};
RX PubMed=20237561; DOI=10.1038/nature08850;
RA Ma L.J., van der Does H.C., Borkovich K.A., Coleman J.J., Daboussi M.J.,
RA Di Pietro A., Dufresne M., Freitag M., Grabherr M., Henrissat B.,
RA Houterman P.M., Kang S., Shim W.B., Woloshuk C., Xie X., Xu J.R.,
RA Antoniw J., Baker S.E., Bluhm B.H., Breakspear A., Brown D.W.,
RA Butchko R.A., Chapman S., Coulson R., Coutinho P.M., Danchin E.G.,
RA Diener A., Gale L.R., Gardiner D.M., Goff S., Hammond-Kosack K.E.,
RA Hilburn K., Hua-Van A., Jonkers W., Kazan K., Kodira C.D., Koehrsen M.,
RA Kumar L., Lee Y.H., Li L., Manners J.M., Miranda-Saavedra D., Mukherjee M.,
RA Park G., Park J., Park S.Y., Proctor R.H., Regev A., Ruiz-Roldan M.C.,
RA Sain D., Sakthikumar S., Sykes S., Schwartz D.C., Turgeon B.G.,
RA Wapinski I., Yoder O., Young S., Zeng Q., Zhou S., Galagan J., Cuomo C.A.,
RA Kistler H.C., Rep M.;
RT "Comparative genomics reveals mobile pathogenicity chromosomes in
RT Fusarium.";
RL Nature 464:367-373(2010).
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DR EMBL; DS022263; EWG55058.1; -; Genomic_DNA.
DR RefSeq; XP_018761249.1; XM_018902490.1.
DR AlphaFoldDB; W7MU76; -.
DR GeneID; 30070488; -.
DR KEGG; fvr:FVEG_13112; -.
DR VEuPathDB; FungiDB:FVEG_13112; -.
DR eggNOG; KOG1807; Eukaryota.
DR OrthoDB; 7041at2759; -.
DR Proteomes; UP000009096; Chromosome 6.
DR GO; GO:0004386; F:helicase activity; IEA:InterPro.
DR CDD; cd18808; SF1_C_Upf1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR045055; DNA2/NAM7-like.
DR InterPro; IPR041679; DNA2/NAM7-like_C.
DR InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR047187; SF1_C_Upf1.
DR PANTHER; PTHR10887; DNA2/NAM7 HELICASE FAMILY; 1.
DR PANTHER; PTHR10887:SF341; NFX1-TYPE ZINC FINGER-CONTAINING PROTEIN 1; 1.
DR Pfam; PF13086; AAA_11; 1.
DR Pfam; PF13087; AAA_12; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000009096}.
FT DOMAIN 282..660
FT /note="DNA2/NAM7 helicase helicase"
FT /evidence="ECO:0000259|Pfam:PF13086"
FT DOMAIN 673..862
FT /note="DNA2/NAM7 helicase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13087"
FT REGION 473..496
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 984..1046
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1071..1179
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1007..1041
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1082..1112
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1124..1157
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1158..1179
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1179 AA; 133251 MW; A46C17C2BD129C8C CRC64;
MGDQYQQIPR DQTTSEIITQ HVKHKNNLPK TGSVPWHLAP EFPHSSELMS IDPAPLPPPP
IIKELSGRDA KNAYLEFQYI TNRFEGTELL RQAINCFRNK PRMMEGDRDN FYIYTQVHVQ
GYLFARSGAA CRIAFSTERS PTKVEWKQTN RLTAGTLIAL SPKDDNFNTE CYVAVVAARY
IVGGLEPDLA NGEGKDTPPR IEIFWSDCNN AVFDPSVEMV MLEAKGGYFE TVRHAMVGLQ
HAAKFDSKFD KYIIHESNTE HTTAYLADIP GQTPHIPERA DHLDHSQKEA LERMTHKELA
VIQGPPGTGK TFTSVVAIES YIKTLKSGKE APPVIVAAQT NHALDQLLDR LSVFEAVIVR
LGGRTEDEAI EERTLFNLKA KLGHKSGGSI AGEQARRTVL GTIETLLSEC FPAFLIPAEE
FLREGLLSDA QYKSLDDDEW ESATLVNRDD GTEVECRIAH WLQVIEDDHT LDIRPPQNQA
ENPAKDDAVE ETQQENQKER LKGAFFPMKY NVTGALPSAL SKHAAWVHRA RRLLKLHQDL
YKIKPGDRGM VYRLLREELI RARAQKFPQL LKEYQEACDD IKVQRWENDV KLITHERIEI
VGCTTTGLSK YRGMIAALKP RILMIEEAAE TREANISSAL YPSLGQVVLV GDHQQLVPSV
DVRELGRDPY NMHVSLFERL VKLKLPYSML RVQRRMVPAI REVVNAFYPK LTDHCSVYDP
DNRPPIPGMG GKSLWWFDHE GQEVQIANDF SFSNPDEADM IVGFVRYLVQ NGVDPERITI
LTFYKGQVAL ITEKLRRDLY LELKNPLKKW SVRTVDGFQG EENDVILLSL VRTVGPGFIG
NSNRANVGTS RARCGMYVFG NSQTLVRDEN SEAYSTWRKV IDVFEQRQCI DDYLPVTCRN
HGTRTNIKNA SGWKYIPGGG CDKGCESTCS KGHPCKLTCH KFDHSEVKCL EKCEEVLNCG
HSCESLCWQP CKCPSRCDEP PKMKLPLRTS PLPARASKRP NHRPQSRSDR TISGGSSHQT
SPTRRSDPFQ APSSLVPTST PMAQARKHCL EPTSEQIMEV GYYAETMQQV HQGADASKEG
SRPDNWSPEK LAKNDKLLAE DAKAKRGKKS PELIQISETW HRTTTSDNLD RRREEKVETH
WSMKVSTCKK AELGQEKPTE DDEDEGEDED EDNDLISFD
//
