ID W7PY49_9GAMM Unreviewed; 830 AA.
AC W7PY49;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=Diguanylate cyclase {ECO:0008006|Google:ProtNLM};
GN ORFNames=Q427_19220 {ECO:0000313|EMBL:EWH00507.1};
OS Halomonas sp. BC04.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Halomonadaceae; Halomonas.
OX NCBI_TaxID=1403540 {ECO:0000313|EMBL:EWH00507.1, ECO:0000313|Proteomes:UP000019279};
RN [1] {ECO:0000313|EMBL:EWH00507.1, ECO:0000313|Proteomes:UP000019279}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BC04 {ECO:0000313|EMBL:EWH00507.1,
RC ECO:0000313|Proteomes:UP000019279};
RA Farooqui S., Greene A.C., Patel B.K.;
RT "Draft Genome Sequence of Halomonas Strain BC04, an Aromatic-degrading
RT moderate Halophilic Bacterium.";
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EWH00507.1}.
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DR EMBL; AZQX01000225; EWH00507.1; -; Genomic_DNA.
DR RefSeq; WP_051496436.1; NZ_AZQX01000225.1.
DR AlphaFoldDB; W7PY49; -.
DR PATRIC; fig|1403540.3.peg.3598; -.
DR OrthoDB; 8416215at2; -.
DR Proteomes; UP000019279; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd06225; HAMP; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR33121; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR PANTHER; PTHR33121:SF71; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF00672; HAMP; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00304; HAMP; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50113; PAC; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000019279};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..29
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 172..196
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 197..249
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 334..391
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 422..554
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 563..817
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 830 AA; 92914 MW; D38EFBA546BE7A6C CRC64;
MKLLRLSLIS IVGCLLGLAI LVLMGVYSLS KMQDRHDELA SLTALQSRID NFSVASDNLL
LQSADPALWA AYRDEAAAIQ AGLTPLAEEH PGAQRAIRHI GYIVEELSRF YARQDDRSSV
TRDDRLSSGP LALPLRSQII MSQVAGYGVA MDTALQEVVR QRQERIATAT QWLAIGFAAA
AGLFGALCVV SFGLIFKRIN GPLRALSHAA RRAEAGEHDV RVPIVGSDEF ADLSRTFNQM
LDQQDTMVET LSGALATRRA LIDSLPAHIA LLDGAGKILD VNDQWRHFAT ANDFLDSTFG
VGSNYLSVCR AAVGACADEA LDAGNGLQDV LNGNRDSFTL EYPCHSPNQQ RWFRMMASRL
APGQESAGFL GAVVMHVDIT ERKLAEQELQ RQAYQDPLTG LVNRLGFIEA FSRHVDQHGW
NPQDIIVLLD IREMRNVNDA HGYDIGDRML IKMARRLEKH LCDHTLIGRI SGDQFILFLP
DDQAMGPRER LDALAEIFHR PVRIGDIIIE IGARGGYTLL GEDERSAETL LHEVEIALHE
TRLHDRHEFY RYNREMDRLA QHRIDMTRDL RRALEDDQFE LHYQPKVDLT TGQVVGCEAL
IRWIHPERGM QMPGQFIPVA EQSQLIGPIG NWVLFQACRH LREWQDAGLD LVRVSVNVSV
EQFRLGDFTR KVQEALEIHA IVPSALTLEI TESVFSEESE ALRRQINDLH ALGVRLSLDD
FGTGYSSLLY LQQYPFDEIK IDMGFVRRIL DEPLNRNIVS MILGISQVLG ADTVAEGVEN
TAVRDVLLEL GCRIGQGYYY SMPLEVEDFR WLLEKHSRLP LTPLPSPGGS
//
