ID W7PZ30_9GAMM Unreviewed; 514 AA.
AC W7PZ30;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=3-hydroxyacyl-CoA dehydrogenase {ECO:0000313|EMBL:EWH00817.1};
DE EC=1.1.1.157 {ECO:0000313|EMBL:EWH00817.1};
GN ORFNames=Q427_17430 {ECO:0000313|EMBL:EWH00817.1};
OS Halomonas sp. BC04.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Halomonadaceae; Halomonas.
OX NCBI_TaxID=1403540 {ECO:0000313|EMBL:EWH00817.1, ECO:0000313|Proteomes:UP000019279};
RN [1] {ECO:0000313|EMBL:EWH00817.1, ECO:0000313|Proteomes:UP000019279}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BC04 {ECO:0000313|EMBL:EWH00817.1,
RC ECO:0000313|Proteomes:UP000019279};
RA Farooqui S., Greene A.C., Patel B.K.;
RT "Draft Genome Sequence of Halomonas Strain BC04, an Aromatic-degrading
RT moderate Halophilic Bacterium.";
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Lipid metabolism; butanoate metabolism.
CC {ECO:0000256|ARBA:ARBA00005086}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EWH00817.1}.
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DR EMBL; AZQX01000203; EWH00817.1; -; Genomic_DNA.
DR RefSeq; WP_051496388.1; NZ_AZQX01000203.1.
DR AlphaFoldDB; W7PZ30; -.
DR PATRIC; fig|1403540.3.peg.3265; -.
DR OrthoDB; 5389341at2; -.
DR Proteomes; UP000019279; Unassembled WGS sequence.
DR GO; GO:0008691; F:3-hydroxybutyryl-CoA dehydrogenase activity; IEA:UniProtKB-EC.
DR GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR GO; GO:0044248; P:cellular catabolic process; IEA:UniProt.
DR GO; GO:0006631; P:fatty acid metabolic process; IEA:InterPro.
DR GO; GO:1901575; P:organic substance catabolic process; IEA:UniProt.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR006176; 3-OHacyl-CoA_DH_NAD-bd.
DR InterPro; IPR006108; 3HC_DH_C.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR48075; 3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN; 1.
DR PANTHER; PTHR48075:SF5; 3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN; 1.
DR Pfam; PF00725; 3HCDH; 2.
DR Pfam; PF02737; 3HCDH_N; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 2.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:EWH00817.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000019279}.
FT DOMAIN 20..195
FT /note="3-hydroxyacyl-CoA dehydrogenase NAD binding"
FT /evidence="ECO:0000259|Pfam:PF02737"
FT DOMAIN 200..297
FT /note="3-hydroxyacyl-CoA dehydrogenase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00725"
FT DOMAIN 425..505
FT /note="3-hydroxyacyl-CoA dehydrogenase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00725"
SQ SEQUENCE 514 AA; 55069 MW; 85ADDC96161FE5BB CRC64;
MSTDTSSSSP HVTPAPFRTL GIVGTGAMGR GIAQIAAQAG LAVYLHDQRE GAVAEAREFI
GGMWDRAVQK QRLSEADAER HRASLKEATT LAELAECDIV VEAIVEKLEA KQSLFTELET
ILGERAVLAT NTSSLSVTAI ASACRNPARV IGFHFFNPVP LMKIVEVIPG LRTDGDVTER
VDALGRAMGH FTARTTDTPG FLVNHAGRAY GTEALKILGE SVTDPATIDR ILVDQGGFRM
GPFSLLDLTG LDVSHAVMES IYHQYYEEPR FRPSPLTRQR LAAGLLGRKS GAGFYRYVDG
KPQVPEEPTL PRVAPRPVWI SHDNRDAGQA LSRLVEAAGW PLEAGTTPST EALCLVAPLG
EDATAAALRL DLPAERCVAV DLLAGLERRR SLMTTPATRP DVRDAALALL GHDGTPVSAF
NDSNGFVLQR VVACIVNVGS DIAQQGVAAP DTIDRAVELG LGYPRGPLAM GDHYGSRRIL
AILDNLLAAT GDPRYRASPW LRRRAVLGLS LTTP
//
