ID W7Q5J0_9GAMM Unreviewed; 674 AA.
AC W7Q5J0;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE RecName: Full=Tyrosine protein kinase {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=Q427_20195 {ECO:0000313|EMBL:EWH00298.1};
OS Halomonas sp. BC04.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Halomonadaceae; Halomonas.
OX NCBI_TaxID=1403540 {ECO:0000313|EMBL:EWH00298.1, ECO:0000313|Proteomes:UP000019279};
RN [1] {ECO:0000313|EMBL:EWH00298.1, ECO:0000313|Proteomes:UP000019279}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BC04 {ECO:0000313|EMBL:EWH00298.1,
RC ECO:0000313|Proteomes:UP000019279};
RA Farooqui S., Greene A.C., Patel B.K.;
RT "Draft Genome Sequence of Halomonas Strain BC04, an Aromatic-degrading
RT moderate Halophilic Bacterium.";
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EWH00298.1}.
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DR EMBL; AZQX01000241; EWH00298.1; -; Genomic_DNA.
DR RefSeq; WP_043515947.1; NZ_AZQX01000241.1.
DR AlphaFoldDB; W7Q5J0; -.
DR PATRIC; fig|1403540.3.peg.3779; -.
DR OrthoDB; 9775724at2; -.
DR Proteomes; UP000019279; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0045226; P:extracellular polysaccharide biosynthetic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd05387; BY-kinase; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR025669; AAA_dom.
DR InterPro; IPR032807; GNVR.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005702; Wzc-like_C.
DR NCBIfam; TIGR01007; eps_fam; 1.
DR PANTHER; PTHR32309; TYROSINE-PROTEIN KINASE; 1.
DR PANTHER; PTHR32309:SF13; TYROSINE-PROTEIN KINASE ETK-RELATED; 1.
DR Pfam; PF13614; AAA_31; 1.
DR Pfam; PF13807; GNVR; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Kinase {ECO:0000256|ARBA:ARBA00022777}; Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000019279};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Tyrosine-protein kinase {ECO:0000256|ARBA:ARBA00023137}.
FT TRANSMEM 380..402
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 322..400
FT /note="Tyrosine kinase G-rich"
FT /evidence="ECO:0000259|Pfam:PF13807"
FT DOMAIN 494..607
FT /note="AAA"
FT /evidence="ECO:0000259|Pfam:PF13614"
FT COILED 209..315
FT /evidence="ECO:0000256|SAM:Coils"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EWH00298.1"
SQ SEQUENCE 674 AA; 75635 MW; FD2076F28DBE878F CRC64;
NTSAEIQILQ SRMVLGHAVD RLGQENIIRP VTMPIIGDYV VRQGIQRPDF PIMLPYISDY
VLSSGIPQPS FMQRQPYVWG GENLEVARFV LAEHRRSHVV VVERDSEERY RVMLNEQHIG
DGHIGQLHTF LDGEMELLID EFNAAPGAQF RLAKRNRNGD IRSLGGRLQI AEVGGGRGSS
TGVLRLSMTG PDTQEIVRSL DAVADTFLTQ NVERQSAQAE QSLVFLEEQT PELRHQLTTA
EERLNRYRAE LDSVDLSSEA QAAVQRYIDI ERRINELEFQ EAELAQRYTT SHPSYQTLLR
QKRHLQAEKT QLNNRVNELP TAQQEVLRLT RDVEVTQAIY VNVLNKVQEL QVAKAGTIGN
VRIIDRAEIR GMVAPQQSRI TVLATLLGAT LAVGLVLLRA LFKRGVETPD QIESAGMPVY
ATIPLSNQQQ RLARRVKRWK NKRNTGQDIV VGVLAERDPT DSAVEAIRGL RTSLHFAMLE
GRNHRLMISG PSPGVGKSFV SINLAAVAAQ AGMRVLLIDA DLRKGQNHHA FRLRSEQGLA
DYLAKQLELD DIIKETSIDN LSLITRGMVP PNPSELLMQP RFTEALVQLD KRYDLIILDT
PPVLAVTDAS VVGKHCETSL LVARFEKNPI REIQAAKRRL ENNGFDVQGV ILNAIERKAA
TASSHYGYCY YNYR
//
