ID W7QGK5_9ALTE Unreviewed; 588 AA.
AC W7QGK5;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE RecName: Full=Endoglucanase {ECO:0000256|RuleBase:RU361166};
DE EC=3.2.1.4 {ECO:0000256|RuleBase:RU361166};
GN ORFNames=DS2_05715 {ECO:0000313|EMBL:EWH11041.1};
OS Catenovulum agarivorans DS-2.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Alteromonadaceae; Catenovulum.
OX NCBI_TaxID=1328313 {ECO:0000313|EMBL:EWH11041.1, ECO:0000313|Proteomes:UP000019276};
RN [1] {ECO:0000313|EMBL:EWH11041.1, ECO:0000313|Proteomes:UP000019276}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DS-2 {ECO:0000313|EMBL:EWH11041.1,
RC ECO:0000313|Proteomes:UP000019276};
RX PubMed=24604650;
RA Shan D., Li X., Gu Z., Wei G., Gao Z., Shao Z.;
RT "Draft Genome Sequence of the Agar-Degrading Bacterium Catenovulum sp.
RT Strain DS-2, Isolated from Intestines of Haliotis diversicolor.";
RL Genome Announc. 2:e00144-14(2014).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Endohydrolysis of (1->4)-beta-D-glucosidic linkages in
CC cellulose, lichenin and cereal beta-D-glucans.; EC=3.2.1.4;
CC Evidence={ECO:0000256|RuleBase:RU361166};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 9 (cellulase E) family.
CC {ECO:0000256|PROSITE-ProRule:PRU10059, ECO:0000256|RuleBase:RU361166}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EWH11041.1}.
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DR EMBL; ARZY01000007; EWH11041.1; -; Genomic_DNA.
DR RefSeq; WP_035013713.1; NZ_ARZY01000007.1.
DR AlphaFoldDB; W7QGK5; -.
DR STRING; 1328313.DS2_05715; -.
DR PATRIC; fig|1328313.3.peg.1178; -.
DR eggNOG; COG3291; Bacteria.
DR OrthoDB; 9808897at2; -.
DR Proteomes; UP000019276; Unassembled WGS sequence.
DR GO; GO:0008810; F:cellulase activity; IEA:UniProtKB-EC.
DR GO; GO:0030245; P:cellulose catabolic process; IEA:UniProtKB-KW.
DR CDD; cd02850; E_set_Cellulase_N; 1.
DR Gene3D; 1.50.10.10; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR InterPro; IPR004197; Cellulase_Ig-like.
DR InterPro; IPR001701; Glyco_hydro_9.
DR InterPro; IPR033126; Glyco_hydro_9_Asp/Glu_AS.
DR InterPro; IPR018221; Glyco_hydro_9_His_AS.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR PANTHER; PTHR22298; ENDO-1,4-BETA-GLUCANASE; 1.
DR PANTHER; PTHR22298:SF29; ENDOGLUCANASE; 1.
DR Pfam; PF02927; CelD_N; 1.
DR Pfam; PF00759; Glyco_hydro_9; 1.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
DR PROSITE; PS00592; GH9_2; 1.
DR PROSITE; PS00698; GH9_3; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277,
KW ECO:0000256|PROSITE-ProRule:PRU10059};
KW Cellulose degradation {ECO:0000256|RuleBase:RU361166};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|PROSITE-
KW ProRule:PRU10059};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU10059};
KW Polysaccharide degradation {ECO:0000256|ARBA:ARBA00023326,
KW ECO:0000256|PROSITE-ProRule:PRU10059};
KW Reference proteome {ECO:0000313|Proteomes:UP000019276}.
FT DOMAIN 48..125
FT /note="Cellulase Ig-like"
FT /evidence="ECO:0000259|Pfam:PF02927"
FT DOMAIN 137..580
FT /note="Glycoside hydrolase family 9"
FT /evidence="ECO:0000259|Pfam:PF00759"
FT ACT_SITE 517
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10059"
FT ACT_SITE 559
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10060"
FT ACT_SITE 568
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10060"
SQ SEQUENCE 588 AA; 65002 MW; 5C88DD33DFEDDC05 CRC64;
MKKQLFSGCA IGLSAVLLIG CQGTDNIASE SSIQAPSKPK QQPADEVAAV LYNQIGYQAN
MAKLIYLQAN NALTVDVVDR NNQQSVISKL TSEAQFWPHA GKNFVELDLT ELSQVGEYQI
VIDGEVLASF RVANDVYTRA TKIIAQGFYF NRASHEISFE YGGKFNRAAG HMDQQVKIHH
SAASAHRPEG TVVPSPKGWY DAGDYNKYTV NSAISMYTML RAYLKHPSFF QQLKLNIPEQ
FNSTADILDE LFWQLDWFLT MQDPNDGGVY HKVTTLNFSG KIMPEAGLEP RYMIAKSIGA
SLDFAATTAY FARHLQDIDA ERAKLCAQAA EQAYKWAKAN PDKIYVQPDD VKTGAYVVTG
DDYSDEWFWA AAELALTFDA KDYWQDLTQL QAIEMSVPTW SDVQGLGWIS LAEEANAQQW
QYKAQQKLKA LAEHMSIMAN QSAIKVSLGV FDDDFVWGSN GNMANHIMVL DAAKAYVADP
ASLNRLIATN LDYIFGTNPT GYSFVSGLGS QTPMHLHHRV SEADDVLDPV PGLVAGGPHA
GQQDQCDYPS KFPALSYVDD WCSYATNETA INWNAPLLYA VASVASEE
//
