ID W7TQ51_9STRA Unreviewed; 664 AA.
AC W7TQ51;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 22-FEB-2023, entry version 27.
DE SubName: Full=X-ray repair cross-complementing protein 6 {ECO:0000313|EMBL:EWM28192.1};
GN ORFNames=Naga_100004g147 {ECO:0000313|EMBL:EWM28192.1};
OS Nannochloropsis gaditana.
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; Eustigmatophyceae;
OC Eustigmatales; Monodopsidaceae; Nannochloropsis.
OX NCBI_TaxID=72520 {ECO:0000313|EMBL:EWM28192.1, ECO:0000313|Proteomes:UP000019335};
RN [1] {ECO:0000313|EMBL:EWM28192.1, ECO:0000313|Proteomes:UP000019335}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B-31 {ECO:0000313|EMBL:EWM28192.1,
RC ECO:0000313|Proteomes:UP000019335};
RX PubMed=23966634; DOI=10.1093/mp/sst120;
RA Corteggiani Carpinelli E., Telatin A., Vitulo N., Forcato C., D'Angelo M.,
RA Schiavon R., Vezzi A., Giacometti G.M., Morosinotto T., Valle G.;
RT "Chromosome Scale Genome Assembly and Transcriptome Profiling of
RT Nannochloropsis gaditana in Nitrogen Depletion.";
RL Mol. Plant 7:323-335(2014).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the ku70 family.
CC {ECO:0000256|ARBA:ARBA00005240}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EWM28192.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AZIL01000352; EWM28192.1; -; Genomic_DNA.
DR AlphaFoldDB; W7TQ51; -.
DR EnsemblProtists; EWM28192; EWM28192; Naga_100004g147.
DR OrthoDB; 21093at2759; -.
DR Proteomes; UP000019335; Chromosome 5.
DR GO; GO:0043564; C:Ku70:Ku80 complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0042162; F:telomeric DNA binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0006303; P:double-strand break repair via nonhomologous end joining; IEA:InterPro.
DR GO; GO:0000723; P:telomere maintenance; IEA:InterPro.
DR Gene3D; 1.10.1600.10; -; 1.
DR Gene3D; 2.40.290.10; -; 1.
DR Gene3D; 4.10.970.10; Ku70, bridge and pillars; 1.
DR Gene3D; 1.10.720.30; SAP domain; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR006165; Ku70.
DR InterPro; IPR006164; Ku70/Ku80_beta-barrel_dom.
DR InterPro; IPR027388; Ku70_bridge/pillars_dom_sf.
DR InterPro; IPR005160; Ku_C.
DR InterPro; IPR005161; Ku_N.
DR InterPro; IPR003034; SAP_dom.
DR InterPro; IPR036361; SAP_dom_sf.
DR InterPro; IPR016194; SPOC-like_C_dom_sf.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR12604; KU AUTOANTIGEN DNA HELICASE; 1.
DR PANTHER; PTHR12604:SF2; X-RAY REPAIR CROSS-COMPLEMENTING PROTEIN 6; 1.
DR Pfam; PF02735; Ku; 1.
DR Pfam; PF03730; Ku_C; 1.
DR Pfam; PF03731; Ku_N; 1.
DR Pfam; PF02037; SAP; 1.
DR PIRSF; PIRSF003033; Ku70; 1.
DR SMART; SM00559; Ku78; 1.
DR SMART; SM00513; SAP; 1.
DR SUPFAM; SSF68906; SAP domain; 1.
DR SUPFAM; SSF100939; SPOC domain-like; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50800; SAP; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000019335}.
FT DOMAIN 630..664
FT /note="SAP"
FT /evidence="ECO:0000259|PROSITE:PS50800"
FT REGION 598..621
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 664 AA; 74451 MW; 3864EFDED6FF3ABA CRC64;
MLTEDDMEVN DSADEEDGFS KDFDVIEDNL MVLIDARPPM LVENVQGTVP LVTALGIIHH
VLKRKIMINQ RDHVGILLFG AEAVDEKGEI VGSGNAKFSD MSRMSQVWGN QVHELQTLGQ
PTAKRIKQIE RLCHEDTNIM NGLCLKHAQK LPGSSTSAAL RDGLRACLRM LEGQSRKELD
SRRIWLFTNE DDPSQVNDPS QVIKDAREGG VEMWVWHFPA QDGREFNRNK FYEPLLAAPT
RFVQDGYKIA DEKDPGYCTK MIDAGSGDVN SLLLGARTPL FKKRRYVRTK LHISVDPPIS
LDVAFYKTIQ RCRKPMPVKL AAVSNRRLAT STKWMCEDLV QYVDPELDVA CGLEFGKGGV
TIPLHSAAYE MKQRVCQRDP GLHLLAFLPA EELAWELNVT SSTLIYPEEM ALKGCTRAFS
AIRKAMLQQH KMALVRLHIN AVSYPRLAVL LAPPATPGLE LIVLPFLDDL RAIESPHLES
LPALPSMDQK EAAKSVISRL AMRWEEYYQG YSNPGLQKFY AGLQALALEQ SEVDWNESAD
DRTWPDEKEL LGRTGEAMRG LWESSRDPDK VLNGGSSGKR KSTVAGVDRL LSLKKEKREV
KDSGKAEKGH HDSVKSEFEA FEGAQTREGL SKLTVRKLKD LCQELKLHVS GRKDDLIDRL
LSQG
//
