ID W7TSM4_9STRA Unreviewed; 709 AA.
AC W7TSM4;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN ORFNames=Naga_100007g72 {ECO:0000313|EMBL:EWM29177.1};
OS Nannochloropsis gaditana.
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; Eustigmatophyceae;
OC Eustigmatales; Monodopsidaceae; Nannochloropsis.
OX NCBI_TaxID=72520 {ECO:0000313|EMBL:EWM29177.1, ECO:0000313|Proteomes:UP000019335};
RN [1] {ECO:0000313|EMBL:EWM29177.1, ECO:0000313|Proteomes:UP000019335}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B-31 {ECO:0000313|EMBL:EWM29177.1,
RC ECO:0000313|Proteomes:UP000019335};
RX PubMed=23966634; DOI=10.1093/mp/sst120;
RA Corteggiani Carpinelli E., Telatin A., Vitulo N., Forcato C., D'Angelo M.,
RA Schiavon R., Vezzi A., Giacometti G.M., Morosinotto T., Valle G.;
RT "Chromosome Scale Genome Assembly and Transcriptome Profiling of
RT Nannochloropsis gaditana in Nitrogen Depletion.";
RL Mol. Plant 7:323-335(2014).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC Evidence={ECO:0000256|ARBA:ARBA00001556};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EWM29177.1}.
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DR EMBL; AZIL01000177; EWM29177.1; -; Genomic_DNA.
DR AlphaFoldDB; W7TSM4; -.
DR EnsemblProtists; EWM29177; EWM29177; Naga_100007g72.
DR OrthoDB; 5488182at2759; -.
DR Proteomes; UP000019335; Chromosome 3.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF136; ATP-DEPENDENT RNA HELICASE DHX35-RELATED; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000019335}.
FT DOMAIN 57..224
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 263..439
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 709 AA; 79074 MW; D82EE69A33A99459 CRC64;
MAFWKPGTAA PQLGLERPTG LSETEAGDTI GYNPHYRLPF KQQKLLLPIA RARENILYAL
ERYKTVVLVG ETGSGKSTQV PQYLHESGWT QGDRVVLCTQ PRRVAAITVA ARVAEEMGCK
LGGIVGYAVR FDSRVDEGGS RTRIKFVTDG LLLRETLYDP LLSAYSVIIL DEAHERSMYT
DVLLGLLKKV RKRRPELRIM ISSATADAET FRDFFETFTY KGVSSEQSEG SNHDSTIVSI
TGRQHAVDVF YLSKAPRNYL RSAVDTVLSI IESEGRGDVL VFLPGMEEID EAVVTVKEHL
NALGGMENVV LVLPLHSSLP HHLQMKALQP PSRHVERKVI FATNIAETSL TIEGIRFIVD
CGFVKLPVYD VRTGFESLVT TSVSRASATQ RAGRAGRTGP GKCFRLYTEE AFSTLSAHTT
PEVQRSNLAW MILQLKALGI DQVMTFDFIA QPSAEALMRG LELLYALGAL DDRCRLTPDL
GEKMAEFPVE PRLAKLLLAS FDFHCTEEAL TLVALLQVQN VWTNPKGRES RTIQEAAMAE
LASRDGDHLT LLAIYREWEE AGRSTEWCSE HFLNPRSLTR AREIRGQLRR YLERYKPKGS
VFASCVDDSE ALRRCVLTGF FFNAARLKSD GRYYTVRDGH PVALHSTSVL AKYGAPAEWI
VYNDVVITSE PFLRDCSRIQ PLWLMELAPH FYAYGGGKGT SISTSTNIC
//
