ID W7TSW1_9STRA Unreviewed; 764 AA.
AC W7TSW1;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Trna pseudouridine synthase 3 {ECO:0000313|EMBL:EWM23621.1};
GN ORFNames=Naga_100137g19 {ECO:0000313|EMBL:EWM23621.1};
OS Nannochloropsis gaditana.
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; Eustigmatophyceae;
OC Eustigmatales; Monodopsidaceae; Nannochloropsis.
OX NCBI_TaxID=72520 {ECO:0000313|EMBL:EWM23621.1, ECO:0000313|Proteomes:UP000019335};
RN [1] {ECO:0000313|EMBL:EWM23621.1, ECO:0000313|Proteomes:UP000019335}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B-31 {ECO:0000313|EMBL:EWM23621.1,
RC ECO:0000313|Proteomes:UP000019335};
RX PubMed=23966634; DOI=10.1093/mp/sst120;
RA Corteggiani Carpinelli E., Telatin A., Vitulo N., Forcato C., D'Angelo M.,
RA Schiavon R., Vezzi A., Giacometti G.M., Morosinotto T., Valle G.;
RT "Chromosome Scale Genome Assembly and Transcriptome Profiling of
RT Nannochloropsis gaditana in Nitrogen Depletion.";
RL Mol. Plant 7:323-335(2014).
CC -!- SIMILARITY: Belongs to the tRNA pseudouridine synthase TruA family.
CC {ECO:0000256|ARBA:ARBA00009375}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EWM23621.1}.
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DR EMBL; AZIL01001546; EWM23621.1; -; Genomic_DNA.
DR AlphaFoldDB; W7TSW1; -.
DR EnsemblProtists; EWM23621; EWM23621; Naga_100137g19.
DR OrthoDB; 167554at2759; -.
DR Proteomes; UP000019335; Chromosome 16.
DR GO; GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0001522; P:pseudouridine synthesis; IEA:InterPro.
DR GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR Gene3D; 3.30.70.660; Pseudouridine synthase I, catalytic domain, C-terminal subdomain; 1.
DR Gene3D; 3.30.70.580; Pseudouridine synthase I, catalytic domain, N-terminal subdomain; 1.
DR InterPro; IPR020103; PsdUridine_synth_cat_dom_sf.
DR InterPro; IPR001406; PsdUridine_synth_TruA.
DR InterPro; IPR020097; PsdUridine_synth_TruA_a/b_dom.
DR InterPro; IPR020095; PsdUridine_synth_TruA_C.
DR InterPro; IPR020094; TruA/RsuA/RluB/E/F_N.
DR PANTHER; PTHR11142; PSEUDOURIDYLATE SYNTHASE; 1.
DR PANTHER; PTHR11142:SF5; TRNA PSEUDOURIDINE(38_39) SYNTHASE; 1.
DR Pfam; PF01416; PseudoU_synth_1; 1.
DR SUPFAM; SSF55120; Pseudouridine synthase; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Reference proteome {ECO:0000313|Proteomes:UP000019335};
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694}.
FT DOMAIN 329..455
FT /note="Pseudouridine synthase I TruA alpha/beta"
FT /evidence="ECO:0000259|Pfam:PF01416"
FT REGION 23..54
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 192..214
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 519..584
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 670..764
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 192..211
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 676..690
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 691..715
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 716..741
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 764 AA; 83011 MW; 36F4FF3EF224EE47 CRC64;
MPSPCINIKS RAFTAQGCMK TAQGHVEGPA PESCTGLDQD AHLPFQSPSP PLPQDLTRSQ
LYSMLRHIQE QTDGKALVGH ALHHILSLAT GSTPHPPPKK QKSARGFDFS RFGTRHIAIQ
FSYEGGPYNG LTSNGPNEEE SVEAQLLMAC IKTKLIPDRA SACVSRCGRT DRGVNALRQV
VGLRVRSILS TPSTSPWPPA CASSSSPCAS PDQHAPRVIP DANGDADSYN EHAETTVTGG
FFKEEAEDPA LDPAALAAGG NIWSASYDTR TEGELDYTTL LNRVLPLDIR VLGWAPVPDG
FSARFCCSYR TYRYFFDGDG YDLGRMSAAA GRLVGEHDFR NFCKMDVTTV QSFVRVVREA
TVLTAGEWGW ALDSRGPMPG PSSTPARRVC CLQIQGQAFL WHMVRCIMAV LFAVGRGQEE
VGVVDDLLDV SRYPGKPLYA LASEHALVLH DCHFERLRFH HQPSALFRLW TELRLAWGQT
AVRLARLQDQ MGYVGELAVR KAALDGWVDA ELGMGRFQGS RFQKQEKKKK GKRREAGGGE
GAGTAGGGGG EGGSKTCEAM NNESGSVHGV SDRGGEAEDE KSVGKKEDTV LMTWRDALAY
LSAQGIVPDL EVSKKKKGIW TPYVPLKDRP LGKTYEEAVL GMGTKKRELY EQAQRKRKAA
ETKGGMEAFF HNMRGTSPGP SLSSSGRKSP HDKNVINDDV SAAKRKPHRT SDSELNRLNH
LAASSSHDGA NINSQARSEN DLLSHKGLGH GGKSAVQHAT AWPN
//
