ID W7TYT3_9STRA Unreviewed; 826 AA.
AC W7TYT3;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 08-NOV-2023, entry version 26.
DE SubName: Full=Transketolase {ECO:0000313|EMBL:EWM25554.1};
GN Name=PDH {ECO:0000313|EMBL:EWM25554.1};
GN ORFNames=Naga_100130g6 {ECO:0000313|EMBL:EWM25554.1};
OS Nannochloropsis gaditana.
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; Eustigmatophyceae;
OC Eustigmatales; Monodopsidaceae; Nannochloropsis.
OX NCBI_TaxID=72520 {ECO:0000313|EMBL:EWM25554.1, ECO:0000313|Proteomes:UP000019335};
RN [1] {ECO:0000313|EMBL:EWM25554.1, ECO:0000313|Proteomes:UP000019335}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B-31 {ECO:0000313|EMBL:EWM25554.1,
RC ECO:0000313|Proteomes:UP000019335};
RX PubMed=23966634; DOI=10.1093/mp/sst120;
RA Corteggiani Carpinelli E., Telatin A., Vitulo N., Forcato C., D'Angelo M.,
RA Schiavon R., Vezzi A., Giacometti G.M., Morosinotto T., Valle G.;
RT "Chromosome Scale Genome Assembly and Transcriptome Profiling of
RT Nannochloropsis gaditana in Nitrogen Depletion.";
RL Mol. Plant 7:323-335(2014).
CC -!- COFACTOR:
CC Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC Evidence={ECO:0000256|ARBA:ARBA00001964};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EWM25554.1}.
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DR EMBL; AZIL01000926; EWM25554.1; -; Genomic_DNA.
DR AlphaFoldDB; W7TYT3; -.
DR EnsemblProtists; EWM25554; EWM25554; Naga_100130g6.
DR OrthoDB; 294935at2759; -.
DR Proteomes; UP000019335; Chromosome 11.
DR GO; GO:0004739; F:pyruvate dehydrogenase (acetyl-transferring) activity; IEA:UniProtKB-EC.
DR CDD; cd02000; TPP_E1_PDC_ADC_BCADC; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 2.
DR InterPro; IPR001017; DH_E1.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR InterPro; IPR033248; Transketolase_C.
DR PANTHER; PTHR11516:SF60; PYRUVATE DEHYDROGENASE E1 COMPONENT SUBUNIT ALPHA; 1.
DR PANTHER; PTHR11516; PYRUVATE DEHYDROGENASE E1 COMPONENT, ALPHA SUBUNIT BACTERIAL AND ORGANELLAR; 1.
DR Pfam; PF00676; E1_dh; 1.
DR Pfam; PF02779; Transket_pyr; 1.
DR Pfam; PF02780; Transketolase_C; 1.
DR SMART; SM00861; Transket_pyr; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 2.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000019335}.
FT DOMAIN 493..668
FT /note="Transketolase-like pyrimidine-binding"
FT /evidence="ECO:0000259|SMART:SM00861"
FT REGION 54..80
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 826 AA; 88382 MW; 54CEEACBEDE7DC39 CRC64;
MSPFVFIRLI MRISMRLALF AGAGLATTST AFLNPSSFLS TTSRPIQETT RATPLQAAPA
ATAARVTATD RPTYNEDPEA MARGQMRPRP EDLGWEQVKA QLNTAFGLTE NSLGKYDTVG
KADLLKAYTM MEVSRQFENA CNQAYMQGKI RGFMHLDNGQ ESIPALVSDA IKAGDIKHSY
YREHTHALAS GVPAENVMAE LFAKVDGTCK GAGGSMHIYD VSKNFQGGWA LVSEQLPYAV
GAARSILLDR ELDTEGKKDD DRITIVFIGE GGAQNGRMAE CLNAAAKEGL PILFLVIDNG
RAINTFTPDV AANSDVFKAG MHYGIPGVKV DGQNMADTLK TGRAVVDYVR EKGPAILQVH
TYRFTGHSPA DPEHERGRKE EKRWARAEAD PIVIFEEVTA PANGITEADL EACRAEAKAT
VKKAVEFADA SSPPPAGLAK ELEYPDAPNT DYNLRAPPAG AEAITKKTVD GAALAACKEY
IALLRSNSEK NMLTIGDAVN LAILEEMVRD PTTTIHAEDL QAGSSYNIPK LTQQTFGKLR
AADEIIDEGH FIGKALGEAM NGYRPIVELM NTNFGIYGLA EISSAGNTYA TTGGQFLMPM
TIIGAGGTAP NQALGAEHSQ PFHAYVMGIP GLKICTAASP YAAYGLTKSM IRDNGPGILF
LPVKLMKEIK GNAPVDQCLP MNKAVALSAA SDAAVLAGKA VTVLTYLHGV KESQIAQAAI
AERDPSVEID LIELRSLKPL DMDTIRASLS RTHKLAILDE STSSGGVGAT ISALVSEQCY
DELDAPVKRL CMDDAPVPYA SSMEKAVVKR STDLVDAVFD LVAGRV
//
