ID W7U225_9STRA Unreviewed; 568 AA.
AC W7U225;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Pseudouridine family {ECO:0000313|EMBL:EWM26704.1};
GN Name=RluD {ECO:0000313|EMBL:EWM26704.1};
GN ORFNames=Naga_100001g174 {ECO:0000313|EMBL:EWM26704.1};
OS Nannochloropsis gaditana.
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; Eustigmatophyceae;
OC Eustigmatales; Monodopsidaceae; Nannochloropsis.
OX NCBI_TaxID=72520 {ECO:0000313|EMBL:EWM26704.1, ECO:0000313|Proteomes:UP000019335};
RN [1] {ECO:0000313|EMBL:EWM26704.1, ECO:0000313|Proteomes:UP000019335}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B-31 {ECO:0000313|EMBL:EWM26704.1,
RC ECO:0000313|Proteomes:UP000019335};
RX PubMed=23966634; DOI=10.1093/mp/sst120;
RA Corteggiani Carpinelli E., Telatin A., Vitulo N., Forcato C., D'Angelo M.,
RA Schiavon R., Vezzi A., Giacometti G.M., Morosinotto T., Valle G.;
RT "Chromosome Scale Genome Assembly and Transcriptome Profiling of
RT Nannochloropsis gaditana in Nitrogen Depletion.";
RL Mol. Plant 7:323-335(2014).
CC -!- SIMILARITY: Belongs to the pseudouridine synthase RluA family.
CC {ECO:0000256|ARBA:ARBA00010876}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EWM26704.1}.
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DR EMBL; AZIL01000609; EWM26704.1; -; Genomic_DNA.
DR AlphaFoldDB; W7U225; -.
DR EnsemblProtists; EWM26704; EWM26704; Naga_100001g174.
DR OrthoDB; 5479603at2759; -.
DR Proteomes; UP000019335; Chromosome 8.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0001522; P:pseudouridine synthesis; IEA:InterPro.
DR CDD; cd02869; PseudoU_synth_RluA_like; 1.
DR CDD; cd00165; S4; 1.
DR Gene3D; 3.30.2350.10; Pseudouridine synthase; 2.
DR Gene3D; 3.10.290.10; RNA-binding S4 domain; 1.
DR InterPro; IPR020103; PsdUridine_synth_cat_dom_sf.
DR InterPro; IPR006224; PsdUridine_synth_RluA-like_CS.
DR InterPro; IPR006145; PsdUridine_synth_RsuA/RluA.
DR InterPro; IPR002942; S4_RNA-bd.
DR InterPro; IPR036986; S4_RNA-bd_sf.
DR PANTHER; PTHR21600; MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE; 1.
DR PANTHER; PTHR21600:SF44; PSEUDOU_SYNTH_2 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00849; PseudoU_synth_2; 1.
DR SMART; SM00363; S4; 1.
DR SUPFAM; SSF55174; Alpha-L RNA-binding motif; 1.
DR SUPFAM; SSF55120; Pseudouridine synthase; 1.
DR PROSITE; PS01129; PSI_RLU; 1.
DR PROSITE; PS50889; S4; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000019335};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00182};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..28
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 152..218
FT /note="RNA-binding S4"
FT /evidence="ECO:0000259|SMART:SM00363"
FT REGION 93..127
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 568 AA; 62598 MW; 89CFD4BFE7383ADC CRC64;
MAKCPPDGTT IAFFSSVHFL IFVMGIYLKT SDGFICPRGG MQRLSLSPCP QQRTVFAMMA
GRKPPWQRRG PDKKQDSEDE LWVLEQSLLN GSSPRTSAFV PSITPTSKTS SSTPEKTDNT
LKDTDGNFGT LRDEANITAQ FMFVANTSES LIRVDRLLTQ RLKGHSRSSV CDLLDRGFVY
VNGSPARKSL KIVEGDEIFV RQCATNERLA EVEEEDIPLD VLYEDEHVIA VNKAPGMVVH
PAPGNRNGTF VNALLAHVAR RGGEIEEVVG SEGRPGVVHR LDKGTSGVLL AAKTARAHAA
LSSAFAERRV NKTYLAISIG NPSSQGAVID VPIGRHPRDR QRMAVAMQAR TSHTSSFPGA
SYAQDAVLNY DGCSEDDQEI GYNSTEGEEL LMGRGGNSGN TPLTGRKARS TVKTLAFDGR
LSVVEVGIET GRTHQIRVHL QHRRNPVLGD ELYGNAQWNA RARRRWGVTR PMLHALRLVV
DHPVTGDPLR LVAPVPPDML SVAHGIWPQV KGRENEEWWD MVDRRPSAGD ESMTDGKDLI
ESQQGWEEVV HDPKAGERVV DEFDWEID
//
