ID   W7XGR1_TETTS            Unreviewed;       132 AA.
AC   W7XGR1;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Aldo/keto reductase family oxidoreductase {ECO:0000313|EMBL:EWS73386.1};
GN   ORFNames=TTHERM_000962008 {ECO:0000313|EMBL:EWS73386.1};
OS   Tetrahymena thermophila (strain SB210).
OC   Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC   Oligohymenophorea; Hymenostomatida; Tetrahymenina; Tetrahymenidae;
OC   Tetrahymena.
OX   NCBI_TaxID=312017 {ECO:0000313|EMBL:EWS73386.1, ECO:0000313|Proteomes:UP000009168};
RN   [1] {ECO:0000313|Proteomes:UP000009168}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SB210 {ECO:0000313|Proteomes:UP000009168};
RX   PubMed=16933976; DOI=10.1371/journal.pbio.0040286;
RA   Eisen J.A., Coyne R.S., Wu M., Wu D., Thiagarajan M., Wortman J.R.,
RA   Badger J.H., Ren Q., Amedeo P., Jones K.M., Tallon L.J., Delcher A.L.,
RA   Salzberg S.L., Silva J.C., Haas B.J., Majoros W.H., Farzad M.,
RA   Carlton J.M., Smith R.K. Jr., Garg J., Pearlman R.E., Karrer K.M., Sun L.,
RA   Manning G., Elde N.C., Turkewitz A.P., Asai D.J., Wilkes D.E., Wang Y.,
RA   Cai H., Collins K., Stewart B.A., Lee S.R., Wilamowska K., Weinberg Z.,
RA   Ruzzo W.L., Wloga D., Gaertig J., Frankel J., Tsao C.-C., Gorovsky M.A.,
RA   Keeling P.J., Waller R.F., Patron N.J., Cherry J.M., Stover N.A.,
RA   Krieger C.J., del Toro C., Ryder H.F., Williamson S.C., Barbeau R.A.,
RA   Hamilton E.P., Orias E.;
RT   "Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a
RT   model eukaryote.";
RL   PLoS Biol. 4:1620-1642(2006).
CC   -!- SIMILARITY: Belongs to the shaker potassium channel beta subunit
CC       family. {ECO:0000256|ARBA:ARBA00006515}.
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DR   EMBL; GG662632; EWS73386.1; -; Genomic_DNA.
DR   RefSeq; XP_012654076.1; XM_012798622.1.
DR   AlphaFoldDB; W7XGR1; -.
DR   STRING; 312017.W7XGR1; -.
DR   GeneID; 24441239; -.
DR   KEGG; tet:TTHERM_000962008; -.
DR   InParanoid; W7XGR1; -.
DR   OrthoDB; 177088at2759; -.
DR   Proteomes; UP000009168; Unassembled WGS sequence.
DR   Gene3D; 3.20.20.100; NADP-dependent oxidoreductase domain; 1.
DR   InterPro; IPR005399; K_chnl_volt-dep_bsu_KCNAB-rel.
DR   InterPro; IPR023210; NADP_OxRdtase_dom.
DR   InterPro; IPR036812; NADP_OxRdtase_dom_sf.
DR   PANTHER; PTHR43150; HYPERKINETIC, ISOFORM M; 1.
DR   PANTHER; PTHR43150:SF2; HYPERKINETIC, ISOFORM M; 1.
DR   Pfam; PF00248; Aldo_ket_red; 1.
DR   SUPFAM; SSF51430; NAD(P)-linked oxidoreductase; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000009168}.
FT   DOMAIN          16..114
FT                   /note="NADP-dependent oxidoreductase"
FT                   /evidence="ECO:0000259|Pfam:PF00248"
SQ   SEQUENCE   132 AA;  14976 MW;  CA42B261673D05F2 CRC64;
     MEYRFLGNSG LKVSAIEFGN WLNSDSSDRK QKMIEIIKRA YTLGINFFDT AEACSQGEGQ
     IQFGEAFKAL GAPRQEIVIS SKIFWVAPPT SVDIKKFNQI GLSRKHILEG VKVSWFKEIS
     IRLLRYSLLS QI
//