ID W8EUS3_9BACT Unreviewed; 321 AA.
AC W8EUS3;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Glycoside hydrolase family protein {ECO:0000313|EMBL:AHJ95487.1};
GN ORFNames=Hsw_PA0154 {ECO:0000313|EMBL:AHJ95487.1};
OS Hymenobacter swuensis DY53.
OG Plasmid pHsw1 {ECO:0000313|EMBL:AHJ95487.1,
OG ECO:0000313|Proteomes:UP000019423}.
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Hymenobacteraceae;
OC Hymenobacter.
OX NCBI_TaxID=1227739 {ECO:0000313|EMBL:AHJ95487.1, ECO:0000313|Proteomes:UP000019423};
RN [1] {ECO:0000313|EMBL:AHJ95487.1, ECO:0000313|Proteomes:UP000019423}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DY53 {ECO:0000313|EMBL:AHJ95487.1,
RC ECO:0000313|Proteomes:UP000019423};
RC PLASMID=pHsw1 {ECO:0000313|EMBL:AHJ95487.1,
RC ECO:0000313|Proteomes:UP000019423};
RA Jung J.-H., Jeong S.-W., Joe M.-H., Cho y.-j., Kim M.-K., Lim S.-Y.;
RT "Complete sequence of plasmid1 of ionizing-radiation resistance bacterium
RT Hymenobacter swuensis DY53.";
RL Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 43 family.
CC {ECO:0000256|ARBA:ARBA00009865, ECO:0000256|RuleBase:RU361187}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP007144; AHJ95487.1; -; Genomic_DNA.
DR RefSeq; WP_044000406.1; NZ_CP007144.1.
DR AlphaFoldDB; W8EUS3; -.
DR KEGG; hsw:Hsw_PA0154; -.
DR PATRIC; fig|1227739.3.peg.182; -.
DR eggNOG; COG3507; Bacteria.
DR HOGENOM; CLU_009397_4_1_10; -.
DR OrthoDB; 3308423at2; -.
DR Proteomes; UP000019423; Plasmid pHsw1.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR CDD; cd18618; GH43_Xsa43E-like; 1.
DR InterPro; IPR006710; Glyco_hydro_43.
DR InterPro; IPR023296; Glyco_hydro_beta-prop_sf.
DR PANTHER; PTHR43772:SF6; -; 1.
DR PANTHER; PTHR43772; ENDO-1,4-BETA-XYLANASE; 1.
DR Pfam; PF04616; Glyco_hydro_43; 1.
DR SUPFAM; SSF75005; Arabinanase/levansucrase/invertase; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00022651};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361187};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361187};
KW Plasmid {ECO:0000313|EMBL:AHJ95487.1};
KW Polysaccharide degradation {ECO:0000256|ARBA:ARBA00022651};
KW Reference proteome {ECO:0000313|Proteomes:UP000019423};
KW Signal {ECO:0000256|SAM:SignalP};
KW Xylan degradation {ECO:0000256|ARBA:ARBA00022651}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..321
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004907958"
FT ACT_SITE 35
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-1"
FT ACT_SITE 211
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-1"
FT SITE 165
FT /note="Important for catalytic activity, responsible for
FT pKa modulation of the active site Glu and correct
FT orientation of both the proton donor and substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-2"
SQ SEQUENCE 321 AA; 36441 MW; 035FD53F6AE05DA5 CRC64;
MKNRFFLLLV FLLIALATTD LRAQNPIIRD VFTADPAPLV YRDTLFLYTS HDTASVQETN
YKMPDWRIYS TTDMVHWKDY GTRLSPRLFA WATGDAYAAQ CVYHKGKFYW FISTFHQKDD
NSQGGAAIGV AVSDRPTGPF TDAIGKALIT NEMTKDLPHA WDDIDPTVFV DDDQQVYLYW
GNGSCRWVRL KDSMTALAGP ITTFTPQNYI EGPWVYKRRK LYYLVYASAG TKPEMIEYCT
APSATGPWTY RGIIQQNVLN SFTTHPGIID YKGQSYFFYH NGALPTGGSY RRSICVDDLR
YNPDGTIQPI VQTTTGVAPI K
//
