ID W8F1T4_9BACT Unreviewed; 495 AA.
AC W8F1T4;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 24-JAN-2024, entry version 43.
DE RecName: Full=Exodeoxyribonuclease 7 large subunit {ECO:0000256|RuleBase:RU004355};
DE EC=3.1.11.6 {ECO:0000256|RuleBase:RU004355};
GN ORFNames=Hsw_0941 {ECO:0000313|EMBL:AHJ96536.1};
OS Hymenobacter swuensis DY53.
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Hymenobacteraceae;
OC Hymenobacter.
OX NCBI_TaxID=1227739 {ECO:0000313|EMBL:AHJ96536.1, ECO:0000313|Proteomes:UP000019423};
RN [1] {ECO:0000313|EMBL:AHJ96536.1, ECO:0000313|Proteomes:UP000019423}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DY53 {ECO:0000313|EMBL:AHJ96536.1,
RC ECO:0000313|Proteomes:UP000019423};
RA Jung J.-H., Jeong S.-W., Joe M.-H., Cho y.-j., Kim M.-K., Lim S.-Y.;
RT "Complete genome sequence of ionizing-radiation resistance bacterium
RT Hymenobacter swuensis DY53.";
RL Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-
CC direction to yield nucleoside 5'-phosphates.; EC=3.1.11.6;
CC Evidence={ECO:0000256|RuleBase:RU004355};
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|RuleBase:RU004355}.
CC -!- SIMILARITY: Belongs to the XseA family.
CC {ECO:0000256|RuleBase:RU004355}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP007145; AHJ96536.1; -; Genomic_DNA.
DR AlphaFoldDB; W8F1T4; -.
DR STRING; 1227739.Hsw_0941; -.
DR KEGG; hsw:Hsw_0941; -.
DR PATRIC; fig|1227739.3.peg.1188; -.
DR eggNOG; COG1570; Bacteria.
DR HOGENOM; CLU_023625_4_2_10; -.
DR OrthoDB; 9802795at2; -.
DR Proteomes; UP000019423; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009318; C:exodeoxyribonuclease VII complex; IEA:InterPro.
DR GO; GO:0008855; F:exodeoxyribonuclease VII activity; IEA:UniProtKB-EC.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006308; P:DNA catabolic process; IEA:InterPro.
DR CDD; cd04489; ExoVII_LU_OBF; 1.
DR InterPro; IPR003753; Exonuc_VII_L.
DR InterPro; IPR020579; Exonuc_VII_lsu_C.
DR InterPro; IPR025824; OB-fold_nuc-bd_dom.
DR NCBIfam; TIGR00237; xseA; 1.
DR PANTHER; PTHR30008; EXODEOXYRIBONUCLEASE 7 LARGE SUBUNIT; 1.
DR PANTHER; PTHR30008:SF0; EXODEOXYRIBONUCLEASE 7 LARGE SUBUNIT; 1.
DR Pfam; PF02601; Exonuc_VII_L; 1.
DR Pfam; PF13742; tRNA_anti_2; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839, ECO:0000256|RuleBase:RU004355};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU004355};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722, ECO:0000256|RuleBase:RU004355};
KW Reference proteome {ECO:0000313|Proteomes:UP000019423}.
FT DOMAIN 24..132
FT /note="OB-fold nucleic acid binding"
FT /evidence="ECO:0000259|Pfam:PF13742"
FT DOMAIN 159..423
FT /note="Exonuclease VII large subunit C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02601"
SQ SEQUENCE 495 AA; 55398 MW; CDCA985C6FAA94E6 CRC64;
MPLYNRRPDP GLSAPSALPP AALPLSELLA RVRQTLSERF ADSYWVVAEI ADLTLPRSYG
AHCYLTLTDQ HTTARGAQLK AQARATIWSA RYQQLAAAFE EQTGLTLRTG LKVMLRVQVK
FHEQFGLSLD VLALDPTYTV GDLARLRLET LRKLQAEDLL ERQKRLPLPL GVQRVAVISS
PTAAGWQDFV QQLQEAPYDF ALTLFPALMQ GDDAPASIRA ALDGIRPRRH EFDAVVLIRG
GGSKTDLLAF DDYGLAAAIG SFPLPVLTGI GHERDEAVVD LTAHIALKTP TAVAAFLIER
LARLEAALEG YGTRIREVAQ AQVQQAAMQL SRLLRHAHLA AQNQLQDQRE LLHQRIRLAA
TAPRAQLRQQ NHQLTRRQHQ LHRAARTTLR HQEQTLRQRG RLLAQRFRRL HRRRREQLLR
QRFAVQLAAV KLLHRQELQL SQLSAAPAAT TRIQLLTPKG RPVKGPLRPG QEILLRLPDS
VVPARIGGQL PLFLP
//
