ID W8KTC9_9GAMM Unreviewed; 740 AA.
AC W8KTC9;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 24-JAN-2024, entry version 43.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=M911_15135 {ECO:0000313|EMBL:AHK80262.1};
OS Ectothiorhodospira haloalkaliphila.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Chromatiales;
OC Ectothiorhodospiraceae; Ectothiorhodospira.
OX NCBI_TaxID=421628 {ECO:0000313|EMBL:AHK80262.1, ECO:0000313|Proteomes:UP000019442};
RN [1] {ECO:0000313|EMBL:AHK80262.1, ECO:0000313|Proteomes:UP000019442}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A {ECO:0000313|EMBL:AHK80262.1,
RC ECO:0000313|Proteomes:UP000019442};
RX PubMed=25057327; DOI=10.7150/jgen.9123;
RA Singh K.S., Kirksey J., Hoff W.D., Deole R.;
RT "Draft Genome Sequence of the Extremely Halophilic Phototrophic Purple
RT Sulfur Bacterium Halorhodospira halochloris.";
RL J Genomics 2:118-120(2014).
RN [2] {ECO:0000313|Proteomes:UP000019442}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A {ECO:0000313|Proteomes:UP000019442};
RA Singh K.S.;
RT "Draft Genome Sequence of extremely halophilic bacteria Halorhodospira
RT halochloris.";
RL Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP007268; AHK80262.1; -; Genomic_DNA.
DR AlphaFoldDB; W8KTC9; -.
DR KEGG; hhc:M911_15135; -.
DR PATRIC; fig|1354791.3.peg.368; -.
DR HOGENOM; CLU_024784_0_0_6; -.
DR OrthoDB; 9785691at2; -.
DR Proteomes; UP000019442; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR014265; PrsK.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR02916; PEP_his_kin; 1.
DR PANTHER; PTHR43547:SF2; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE C; 1.
DR PANTHER; PTHR43547; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:AHK80262.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000019442};
KW Transferase {ECO:0000313|EMBL:AHK80262.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 37..55
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 139..159
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 171..189
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 201..220
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 269..291
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 303..321
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 522..725
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT REGION 102..123
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 740 AA; 81497 MW; 5417E1C3BE90E845 CRC64;
MDLTFPLGLA SYSIAAGAFV ILLAVLAIGW QRRLQGTLLM VAVALSILWG ATLALNAAHG
QIIGTRMVLL AELARDAGWI AFLWGLLWQA RHLQLARSGE GLATPTQTPR RAGPSAEPEH
DPAHLPGSVA VSGGLGKPLV ALGVGSLVLL LALAVYLGVQ PLLPQAWVRS DIILGGKLLL
VLIVLLLVEQ IFRNTSTEGR WAIKYLCLGL GGVYGFDFYM YAEALLFRQV YAGLWEARGF
VNALVVPLIA VSAARNPQWS LDVYVSRGMV FHTATLLGAG IYLLLMAAAG YYLRVFGGDW
GTVFQAVFLF AALMGLAVFV ISGRFRAQFR VFVSKHFFNY KYDYREEWLR FIQTLADGHR
QEGLPVRVIH ALGDIVDSPA GQLWMRSGGR HFAQVAQRNM TEPAQTSEPR DGPLAAYLLE
TGWVLDIQEA RQCPERYPGL ELPDWLAESE RSWLLVPLKQ ESELLGFVLL APSRARRIIN
WEDRDLLKTA GLQAASHLAQ MEALQALSEA RQFEAFNRLS AYVVHDLKNI IAQLNLVVSN
ARKHGDNPEF LKDAIGTVEN AVSRMNKLML QLRSGDPGRE ARPVNLADLA TQAVNDAQGR
APEPELEHNG GDCPVLADPE RLRSVLNHLI QNAQEATPDN GRVSLSLWQD TRQAYLDVMD
TGTGMTPEFI RERLFRPFDT TKGLTGMGIG AFESREFIRA LGGDLEVWSE TGKGSRFRVS
IPLAQQQTTP LPLENDTTSQ
//
