ID W8RWU2_9RHOB Unreviewed; 599 AA.
AC W8RWU2;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Xaa-Pro aminopeptidase {ECO:0000313|EMBL:AHM05684.1};
DE EC=3.4.11.9 {ECO:0000313|EMBL:AHM05684.1};
GN ORFNames=roselon_03426 {ECO:0000313|EMBL:AHM05684.1};
OS Roseibacterium elongatum DSM 19469.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Roseibacterium.
OX NCBI_TaxID=1294273 {ECO:0000313|EMBL:AHM05684.1, ECO:0000313|Proteomes:UP000019593};
RN [1] {ECO:0000313|EMBL:AHM05684.1, ECO:0000313|Proteomes:UP000019593}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 19469 {ECO:0000313|Proteomes:UP000019593};
RA Fiebig A., Goeker M., Klenk H.-P.P.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase M24B family.
CC {ECO:0000256|ARBA:ARBA00008766}.
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DR EMBL; CP004372; AHM05684.1; -; Genomic_DNA.
DR RefSeq; WP_025313303.1; NZ_CP004372.1.
DR AlphaFoldDB; W8RWU2; -.
DR STRING; 1294273.roselon_03426; -.
DR KEGG; red:roselon_03426; -.
DR PATRIC; fig|1294273.3.peg.3384; -.
DR eggNOG; COG0006; Bacteria.
DR HOGENOM; CLU_011781_2_1_5; -.
DR OrthoDB; 9806388at2; -.
DR Proteomes; UP000019593; Chromosome.
DR GO; GO:0070006; F:metalloaminopeptidase activity; IEA:InterPro.
DR CDD; cd01085; APP; 1.
DR Gene3D; 3.90.230.10; Creatinase/methionine aminopeptidase superfamily; 1.
DR Gene3D; 3.40.350.10; Creatinase/prolidase N-terminal domain; 2.
DR InterPro; IPR029149; Creatin/AminoP/Spt16_NTD.
DR InterPro; IPR036005; Creatinase/aminopeptidase-like.
DR InterPro; IPR000587; Creatinase_N.
DR InterPro; IPR000994; Pept_M24.
DR InterPro; IPR033740; Pept_M24B.
DR InterPro; IPR032416; Peptidase_M24_C.
DR PANTHER; PTHR43763; XAA-PRO AMINOPEPTIDASE 1; 1.
DR PANTHER; PTHR43763:SF6; XAA-PRO AMINOPEPTIDASE 1; 1.
DR Pfam; PF01321; Creatinase_N; 1.
DR Pfam; PF16189; Creatinase_N_2; 1.
DR Pfam; PF00557; Peptidase_M24; 1.
DR Pfam; PF16188; Peptidase_M24_C; 1.
DR SUPFAM; SSF55920; Creatinase/aminopeptidase; 1.
DR SUPFAM; SSF53092; Creatinase/prolidase N-terminal domain; 1.
PE 3: Inferred from homology;
KW Aminopeptidase {ECO:0000313|EMBL:AHM05684.1};
KW Hydrolase {ECO:0000313|EMBL:AHM05684.1};
KW Protease {ECO:0000313|EMBL:AHM05684.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000019593}.
FT DOMAIN 17..151
FT /note="Creatinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01321"
FT DOMAIN 316..527
FT /note="Peptidase M24"
FT /evidence="ECO:0000259|Pfam:PF00557"
FT DOMAIN 540..599
FT /note="Peptidase M24 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16188"
SQ SEQUENCE 599 AA; 64224 MW; 1DE1FB219DBB7C3D CRC64;
MFQEFTATTR PEDGRGRLAA LRAHLARTGV SGCLVPRADR HQGEYVAACD ARLAWLTGFT
GSAGFCAVLP DHAGVFVDGR YRVQVKAQVD GQAFSPVDWP ETKLEEWLAE HVSGGGVIGY
DPWLHTGAEI ARLEGALSKR QISLRPIANP VDAIWADRPA PPDAPARAYP VAHAGKTSVQ
KRTEIAATLR ADGQRAAVLT LPDSVAWLLN IRGGDLPHLP VTQAFAIIED DGRVTVFSDP
AKFEALDLAD AVTVLPWEAF EAALTNLSGP VRVDPATAPV RVAQILDEAG IELAEAPDPC
LLPKARKTTA EIAATTQAHL RDGAAMARFL HWFETEAPKG RLTEIDCVRA LEAFRAETGA
LKDISFDTIA GAGAHGAIVH YRVTEDTNAP VLPGQLFLID SGGQYEDGTT DITRTLPVGA
VGDEEKTAFT QVLQGMIAIH RARFPRGVAG GHLDALARAP LWAAGRDFDH GTGHGVGVYL
SVHEGPQRLS RISTLPLEPG MILSNEPGYY REGAFGIRLE NLVVVREADT PPGGDAHRSM
LAFDTLTWAP IDRGLIRVDM LSPVERDWLN AYHAGVAARI GPLLEGAAAD WLMRATAPV
//
